RNA polymerase II (RNAP II and Pol II) is a multiprotein complex that transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA...
27 KB (3,100 words) - 17:09, 21 April 2024
In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that...
43 KB (5,103 words) - 08:16, 9 September 2024
cells, RNA polymerase III (also called Pol III) is a protein that transcribes DNA to synthesize 5S ribosomal RNA, tRNA, and other small RNAs. The genes...
11 KB (1,365 words) - 00:30, 4 January 2024
RNA polymerase II holoenzyme is a form of eukaryotic RNA polymerase II that is recruited to the promoters of protein-coding genes in living cells. It consists...
37 KB (4,622 words) - 17:05, 6 April 2024
biochemistry, a polymerase is an enzyme (EC 2.7.7.6/7/19/48/49) that synthesizes long chains of polymers or nucleic acids. DNA polymerase and RNA polymerase are used...
7 KB (673 words) - 23:08, 9 July 2024
Transcription (biology) (redirect from RNA transcription)
transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, antiparallel RNA strand called a primary transcript. In virology...
58 KB (6,787 words) - 20:17, 9 August 2024
RNA polymerase 1 (also known as Pol I) is, in higher eukaryotes, the polymerase that only transcribes ribosomal RNA (but not 5S rRNA, which is synthesized...
13 KB (1,695 words) - 16:45, 17 July 2024
Eukaryotic transcription (section RNA polymerase)
non-coding RNAs, including tRNAs, 5S rRNA, U6 snRNA, SRP RNA, and other stable short RNAs such as ribonuclease P RNA. RNA Polymerases I, II, and III contain...
49 KB (5,861 words) - 10:12, 12 August 2024
RNA-dependent RNA polymerase (RdRp) or RNA replicase is an enzyme that catalyzes the replication of RNA from an RNA template. Specifically, it catalyzes...
27 KB (3,099 words) - 15:01, 25 June 2024
Transcription factor II B (TFIIB) is a general transcription factor that is involved in the formation of the RNA polymerase II preinitiation complex (PIC)...
18 KB (2,447 words) - 01:35, 25 July 2024
RNA polymerase V (Pol V), previously known as RNA polymerase IVb, is a multisubunit plant specific RNA polymerase. It is required for normal function...
4 KB (604 words) - 12:45, 22 February 2024
RNA polymerase IV (RNAP IV) is an enzyme that synthesizes small interfering RNA (siRNA) in plants, which silence gene expression. RNAP IV belongs to a...
15 KB (1,821 words) - 09:09, 14 August 2023
POLR2A (redirect from Polymerase polypeptide A)
DNA-directed RNA polymerase II subunit RPB1, also known as RPB1, is an enzyme that is encoded by the POLR2A gene in humans. This gene encodes the largest...
12 KB (1,339 words) - 19:29, 9 April 2024
length of an average snRNA is approximately 150 nucleotides. They are transcribed by either RNA polymerase II or RNA polymerase III. Their primary function...
17 KB (2,325 words) - 18:40, 12 September 2024
Transcription bubble (section RNA polymerase)
from 12 to 14 base pairs. A transcription bubble is formed when the RNA polymerase enzyme binds to a promoter and causes two DNA strands to detach. It...
7 KB (842 words) - 21:36, 21 May 2024
Terminator (genetics) (section Non-mRNAs)
large protein called a Rho factor which exhibits RNA helicase activity to disrupt the mRNA-DNA-RNA polymerase transcriptional complex. Rho-dependent terminators...
13 KB (1,631 words) - 10:55, 5 June 2024
Viroid (redirect from Viroid RNA)
steps through an RNA-based mechanism. They require RNA polymerase II, a host cell enzyme normally associated with synthesis of messenger RNA from DNA, which...
34 KB (3,906 words) - 17:52, 2 May 2024
factors and RNA polymerase II. The main function of mediator complexes is to transmit signals from the transcription factors to the polymerase. Mediator...
32 KB (3,509 words) - 21:28, 12 September 2024
factor II D (TFIID) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. RNA polymerase II holoenzyme...
5 KB (593 words) - 20:14, 3 June 2022
class of RNA polymerase recruited to the site, and species of organism. Promoters control gene expression in bacteria and eukaryotes. RNA polymerase must...
54 KB (6,286 words) - 11:33, 8 August 2024
Α-Amanitin (category RNA polymerase inhibitors)
RNA polymerase II is highly sensitive (inhibited at 1μg/ml), RNA polymerase III is moderately sensitive (inhibited at 10μg/ml), and RNA polymerase IV...
20 KB (2,168 words) - 22:49, 10 August 2024
positions RNA polymerase II (Pol II) at gene transcription start sites, denatures the DNA, and positions the DNA in the RNA polymerase II active site...
11 KB (1,210 words) - 12:30, 16 November 2023
Reverse transcriptase (redirect from RNA-directed DNA polymerase)
information from RNA to DNA are explicitly held possible. Retroviral RT has three sequential biochemical activities: RNA-dependent DNA polymerase activity, ribonuclease...
27 KB (3,043 words) - 03:16, 30 June 2024
DNA-directed RNA polymerase II subunit RPB4 is an enzyme that in humans is encoded by the POLR2D gene. This gene encodes the fourth-largest subunit of RNA polymerase...
8 KB (1,019 words) - 17:04, 11 April 2024
genome surveillance complex (BASC). The BRCA1 protein associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase...
121 KB (13,581 words) - 04:40, 6 September 2024
transcription factors in some eukaryotic genes. Gene transcription by RNA polymerase II depends on the regulation of the core promoter by long-range regulatory...
39 KB (4,785 words) - 21:30, 22 September 2023
RNA polymerase II. The 5' cap is therefore specific to RNAs synthesized by this polymerase rather than those synthesized by RNA polymerase I or RNA polymerase...
14 KB (1,568 words) - 16:39, 7 November 2023
Transcription factor II F (TFIIF) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. TFIIF is encoded...
4 KB (321 words) - 16:57, 27 August 2024
1999). "Physical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53". The Journal of Biological Chemistry...
124 KB (13,220 words) - 11:01, 30 August 2024
the regulation of transcription by RNA polymerase II (Pol II) in eukaryotes. Immediately following initiation Pol II becomes trapped in promoter proximal...
10 KB (1,397 words) - 15:12, 7 July 2024