Saquinavir, sold under the brand name Invirase among others, is an antiretroviral medication used together with other medications to treat or prevent HIV/AIDS...

OX1001 (saquinavir-NO) is an experimental drug being developed by OncoNOx currently undergoing clinical studies and investigations for the treatment of...

Atazanavir Darunavir Fosamprenavir Indinavir Lopinavir Nelfinavir Ritonavir Saquinavir Tipranavir Hepatitis C virus NS3/4A protease inhibitors—class stem –previr: 26 ...

Loperamide can decrease the absorption of some other drugs. As an example, saquinavir concentrations can decrease by half when given with loperamide. Loperamide...

lead to a higher risk of bleeding. Garlic may interact with warfarin, saquinavir, antihypertensives, calcium channel blockers, the quinolone family of...

(3TC) Lopinavir Maraviroc Nelfinavir Nevirapine Raltegravir Ritonavir Saquinavir Tenofovir Tipranavir Zalcitabine (ddC) Zidovudine (AZT) Androstanolone...

antagonists against the HIV protease were revealed in 1987. Phase I trials of saquinavir began in 1989 and it was the first HIV protease inhibitor to be approved...

itraconazole is contraindicated. Other CYP3A4 inhibitors including erythromycin, saquinavir, and verapamil should be used with caution. Other drugs that increase...

Allium sativum has been found to decrease the plasma concentration of saquinavir, and may cause hypoglycemia when taken with chlorpropamide. Ginkgo biloba...

ephedrine is used in bulk quantities as a chiral auxiliary group. In saquinavir synthesis, the half-acid is resolved as its salt with l-ephedrine. In...

United States FDA's approval of Hoffman LaRoche's HIV protease inhibitor, saquinavir. Within 2 years of its approval (and that of ritonavir 4 months later)...

Certain antiretroviral medications (e.g. indinavir, nevirapine, ritonavir, saquinavir, etc.) Progestogens Some anticonvulsants including: carbamazepine, ethosuximide...

(Viagra) tadalafil (Cialis) vardenafil (Levitra) HIV protease inhibitors saquinavir (Invirase) ritonavir (Norvir) nelfinavir (Viracept) amprenavir (Agenerase)...

cell. Also, azole may generate reactive oxygen species. Anti-viral agent Saquinavir HIV protease is needed to cleave Gag-Pol polyprotein into 3 individual...

distortions of the sense of taste, and can be caused by medication, including saquinavir, zonisamide, and various kinds of chemotherapy, as well as occupational...

December 6 – The United States Food and Drug Administration approves Saquinavir, the first protease inhibitor to treat HIV/AIDS. Within 2 years of its...

Barry MG, Mulcahy F, Ryan M, Heavey J, Tjia JF, et al. (March 1997). "Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected...

ketoconazole, lopinavir, nefazodone, nelfinavir, posaconazole, ritonavir, saquinavir, telaprevir, and telithromycin (concomitant use not recommended); the...

A M2 proton channel antagonist Ritonavir HIV HIV-1 protease inhibitor Saquinavir HIV Simeprevir (Olysio) Hepatitis C Sofosbuvir Hepatitis C nucleoside...

people. 1995 – The United States Food and Drug Administration approves Saquinavir, the first protease inhibitor to treat HIV/AIDS. Within 2 years of its...

astemizole, chlorphenamine; protease inhibitors: indinavir, ritonavir, saquinavir, nelfinavir; non-nucleoside reverse-transcriptase inhibitors (antiretroviral...

within their structure, including ciprefadol, dasolampanel, nelfinavir, saquinavir, and tezampanel. CID 97812 from PubChem Okazaki, Hiroshi; Soeda, Mahito;...

from 1,2,3,4-tetrahydroisoquinoline). antiretroviral agents, such as saquinavir with an isoquinolyl functional group, (shown below). vasodilators, a well-known...

the neuraminidase inhibitor oseltamivir and the HIV protease inhibitors saquinavir in the treatment of AIDS. The transition state of a structure can best...

as ketoconazole, itraconazole, clarithromycin, atazanavir, nefazodone, saquinavir, telithromycin, ritonavir, indinavir, nelfinavir, voriconazole) or inducers...

interactions. The first HIV protease inhibitor approved by the FDA was saquinavir, which was designed to target wild-type HIV-1 protease. However, this...

antagonists (except palonosetron), and some antiretrovirals (ritonavir, saquinavir, lopinavir). Escitalopram increases intrasynaptic levels of the neurotransmitter...

darunavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, or saquinavir may experience colchicine toxicity. Grapefruit juice and statins can also...

Omeprazole Orphenadrine Pantoprazole Piperine Quercetin Ranitidine Ritonavir Saquinavir Seproxetine ((S)-norfluoxetine/ Fluoxetine metabolite) Star fruit Telithromycin...

ketoconazole, lopinavir, nefazodone, nelfinavir, posaconazole, ritonavir, saquinavir, telaprevir, and telithromycin (concomitant use not recommended); the...