Steroid sulfatase (STS), or steryl-sulfatase (EC 3.1.6.2), formerly known as arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids...
19 KB (2,144 words) - 04:03, 10 May 2024
X-linked ichthyosis (redirect from Steroid sulfatase deficiency)
XLI) is a skin condition caused by the hereditary deficiency of the steroid sulfatase (STS) enzyme that affects 1 in 2000 to 1 in 6000 males. XLI manifests...
20 KB (2,615 words) - 08:02, 23 August 2024
extracellular spaces. Steroid sulfatase is distributed in a wide range of tissues throughout the body, enabling sulfated steroids synthesized in the adrenals...
6 KB (698 words) - 18:05, 29 October 2023
Steroidogenesis inhibitor (redirect from List of steroid metabolism modulators)
hormonally inactive, some steroid sulfates, such as pregnenolone sulfate and DHEA sulfate, are important neurosteroids. Steroid sulfatase (STS) inhibitors such...
37 KB (2,107 words) - 17:27, 8 June 2024
Arylsulfatase (redirect from Nitrocatechol sulfatase)
(also known as "cerebroside-sulfatase") Arylsulfatase B (also known as "N-acetylgalactosamine-4-sulfatase") Steroid sulfatase (formerly known as "arylsulfatase...
2 KB (219 words) - 06:15, 21 March 2024
Danazol (category Steroid sulfatase inhibitors)
11β-hydroxylase. It has also been found to be a weak inhibitor of steroid sulfatase (Ki = 2.3–8.2 μM), the enzyme that converts DHEA-STooltip dehydroepiandrosterone...
46 KB (3,954 words) - 04:46, 8 April 2024
(3β-HSD), 17β-hydroxysteroid dehydrogenase (17β-HSD), 5α-reductase, and steroid sulfatase (STS), necessary to transform adrenal androgens like DHEA and DHEA-S...
11 KB (1,238 words) - 12:22, 24 January 2024
the ERα and ERβ. However, it can be transformed by steroid sulfatase, also known as estrogen sulfatase, into estrone, an estrogen. Simultaneously, estrogen...
24 KB (2,293 words) - 21:31, 29 March 2024
Steroidogenic enzyme (redirect from Steroid metabolism enzyme)
Steroid sulfatase – steroid synthesis, neurosteroid metabolism Others Aromatase (estrogen synthetase) – estrogen synthesis Inborn errors of steroid metabolism...
6 KB (504 words) - 03:45, 23 November 2023
deletions in the dystrophin gene. It has also been used with the steroid sulfatase gene. In 2008, multiplex-PCR was used for analysis of microsatellites...
7 KB (763 words) - 05:22, 9 June 2024
(ESTs) and the transformation of estrone sulfate into estrone by steroid sulfatase (STS). The metabolic clearance rates and hence blood half-lives of...
223 KB (26,808 words) - 08:46, 18 May 2024
ichthyosis, a form of ichthyosis caused by a hereditary deficiency of the steroid sulfatase (STS) enzyme. It is fairly rare, affecting one in 2,000 to one in...
15 KB (1,754 words) - 13:41, 12 August 2024
Estrone phosphate (category Steroid sulfatase inhibitors)
3-phosphate, is an estrogen and steroid sulfatase inhibitor which was never marketed. It has similar affinity for steroid sulfatase as estrone sulfate and acts...
4 KB (211 words) - 18:43, 3 December 2023
Tibolone (category Steroid sulfatase inhibitors)
cytosolic sulfotransferases and steroid sulfatase in the metabolism of tibolone and raloxifene". The Journal of Steroid Biochemistry and Molecular Biology...
56 KB (5,314 words) - 00:45, 21 March 2024
trisomy 16 mosaicism, fetal death, Smith–Lemli–Opitz syndrome, and steroid sulfatase deficiency. The triple test measures the following three levels in...
12 KB (1,179 words) - 21:19, 28 March 2024
genetic skin disorder caused by the hereditary deficiency of the steroid sulfatase enzyme. Ocular manifestations of XLI include superficial or deep corneal...
24 KB (2,622 words) - 20:06, 8 August 2024
Androsterone sulfate (category 5α-Reduced steroid metabolites)
and can be desulfated back into androsterone by steroid sulfatase. Androsterone glucuronide Steroid sulfate C19H30O5S Mueller JW, Gilligan LC, Idkowiak...
3 KB (119 words) - 22:41, 28 April 2023
highest concentration in the granular layer of the epidermis. Steroid sulfate sulfatase then decreases its concentration in the stratum corneum, the outermost...
80 KB (8,530 words) - 16:20, 22 August 2024
transcriptase inhibitors, HIV protease inhibitors (PIs), anticancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), anti-epileptic drugs, and weight...
15 KB (1,486 words) - 10:15, 26 August 2024
2-Methoxyestradiol disulfamate (category Steroid sulfatase inhibitors)
(2-MeO-E2). It is also a potent inhibitor of steroid sulfatase, the enzyme that catalyzes the desulfation of steroids such as estrone sulfate and dehydroepiandrosterone...
6 KB (455 words) - 12:40, 13 November 2023
Dehydroepiandrosterone (category Anabolic–androgenic steroids)
in turn can be converted back into DHEA in peripheral tissues via steroid sulfatase (STS). The terminal half-life of DHEA is short at only 15 to 30 minutes...
42 KB (3,935 words) - 04:01, 30 April 2024
Chondrodysplasia punctata 1, x-linked recessive Chondrodysplasia punctata with steroid sulfatase deficiency Chondrodysplasia punctata, brachytelephalangic Chondrodysplasia...
40 KB (3,657 words) - 03:02, 17 August 2024
failure. Small genetic deletions on the X chromosome around the STS (steroid sulfatase) gene are associated with increased rates of AF in males; common genetic...
164 KB (18,159 words) - 11:13, 25 August 2024
Cholesterol sulfate (category Steroid esters)
cholesterol sulfotransferase) and is converted back into cholesterol by steroid sulfatase (STS). Accumulation of cholesterol sulfate in the skin is implicated...
3 KB (130 words) - 00:52, 7 February 2020
Androstenediol sulfate (category Steroid stubs)
androstenediol by steroid sulfatase. Steroid sulfate C19H30O5S Mueller JW, Gilligan LC, Idkowiak J, Arlt W, Foster PA (2015). "The Regulation of Steroid Action by...
2 KB (95 words) - 15:35, 9 January 2024
located on the Y chromosome and the Sts (steroid sulfatase) gene. The Sts gene encodes the steroid sulfatase enzyme, which is pivotal in the regulation...
123 KB (14,928 words) - 23:37, 13 August 2024
sarcoma Staurosporine, an antibiotic STS (gene), which codes for steroid sulfatase Superior temporal sulcus Sinus tarsi syndrome, a foot condition Semipalatinsk...
4 KB (483 words) - 14:36, 10 May 2024
are now known to accompany X-linked ichthyosis, steroid sulfatase deficiency, caused by steroid sulfatase gene mutations and are currently usually not included...
15 KB (1,603 words) - 13:02, 12 March 2024
include the estradiol esters estradiol sulfamate (E2MATE; also a potent steroid sulfatase inhibitor) and EC508 (estradiol 17β-(1-(4-(aminosulfonyl)benzoyl)-L-proline))...
12 KB (1,256 words) - 23:27, 4 March 2023
steroid sulfatase and in this way serve as precursors and circulating reservoirs for their active unsulfated counterparts. In addition, some steroid sulfates...
3 KB (235 words) - 21:33, 20 July 2023