Steroid sulfatase (STS), or steryl-sulfatase (EC 3.1.6.2), formerly known as arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids...

XLI) is a skin condition caused by the hereditary deficiency of the steroid sulfatase (STS) enzyme that affects 1 in 2000 to 1 in 6000 males. XLI manifests...

extracellular spaces. Steroid sulfatase is distributed in a wide range of tissues throughout the body, enabling sulfated steroids synthesized in the adrenals...

hormonally inactive, some steroid sulfates, such as pregnenolone sulfate and DHEA sulfate, are important neurosteroids. Steroid sulfatase (STS) inhibitors such...

(also known as "cerebroside-sulfatase") Arylsulfatase B (also known as "N-acetylgalactosamine-4-sulfatase") Steroid sulfatase (formerly known as "arylsulfatase...

11β-hydroxylase. It has also been found to be a weak inhibitor of steroid sulfatase (Ki = 2.3–8.2 μM), the enzyme that converts DHEA-STooltip dehydroepiandrosterone...

(3β-HSD), 17β-hydroxysteroid dehydrogenase (17β-HSD), 5α-reductase, and steroid sulfatase (STS), necessary to transform adrenal androgens like DHEA and DHEA-S...

the ERα and ERβ. However, it can be transformed by steroid sulfatase, also known as estrogen sulfatase, into estrone, an estrogen. Simultaneously, estrogen...

Steroid sulfatase – steroid synthesis, neurosteroid metabolism Others Aromatase (estrogen synthetase) – estrogen synthesis Inborn errors of steroid metabolism...

deletions in the dystrophin gene. It has also been used with the steroid sulfatase gene. In 2008, multiplex-PCR was used for analysis of microsatellites...

(ESTs) and the transformation of estrone sulfate into estrone by steroid sulfatase (STS). The metabolic clearance rates and hence blood half-lives of...

ichthyosis, a form of ichthyosis caused by a hereditary deficiency of the steroid sulfatase (STS) enzyme. It is fairly rare, affecting one in 2,000 to one in...

3-phosphate, is an estrogen and steroid sulfatase inhibitor which was never marketed. It has similar affinity for steroid sulfatase as estrone sulfate and acts...

cytosolic sulfotransferases and steroid sulfatase in the metabolism of tibolone and raloxifene". The Journal of Steroid Biochemistry and Molecular Biology...

trisomy 16 mosaicism, fetal death, Smith–Lemli–Opitz syndrome, and steroid sulfatase deficiency. The triple test measures the following three levels in...

genetic skin disorder caused by the hereditary deficiency of the steroid sulfatase enzyme. Ocular manifestations of XLI include superficial or deep corneal...

and can be desulfated back into androsterone by steroid sulfatase. Androsterone glucuronide Steroid sulfate C19H30O5S Mueller JW, Gilligan LC, Idkowiak...

highest concentration in the granular layer of the epidermis. Steroid sulfate sulfatase then decreases its concentration in the stratum corneum, the outermost...

transcriptase inhibitors, HIV protease inhibitors (PIs), anticancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), anti-epileptic drugs, and weight...

(2-MeO-E2). It is also a potent inhibitor of steroid sulfatase, the enzyme that catalyzes the desulfation of steroids such as estrone sulfate and dehydroepiandrosterone...

in turn can be converted back into DHEA in peripheral tissues via steroid sulfatase (STS). The terminal half-life of DHEA is short at only 15 to 30 minutes...

Chondrodysplasia punctata 1, x-linked recessive Chondrodysplasia punctata with steroid sulfatase deficiency Chondrodysplasia punctata, brachytelephalangic Chondrodysplasia...

failure. Small genetic deletions on the X chromosome around the STS (steroid sulfatase) gene are associated with increased rates of AF in males; common genetic...

cholesterol sulfotransferase) and is converted back into cholesterol by steroid sulfatase (STS). Accumulation of cholesterol sulfate in the skin is implicated...

androstenediol by steroid sulfatase. Steroid sulfate C19H30O5S Mueller JW, Gilligan LC, Idkowiak J, Arlt W, Foster PA (2015). "The Regulation of Steroid Action by...

located on the Y chromosome and the Sts (steroid sulfatase) gene. The Sts gene encodes the steroid sulfatase enzyme, which is pivotal in the regulation...

sarcoma Staurosporine, an antibiotic STS (gene), which codes for steroid sulfatase Superior temporal sulcus Sinus tarsi syndrome, a foot condition Semipalatinsk...

are now known to accompany X-linked ichthyosis, steroid sulfatase deficiency, caused by steroid sulfatase gene mutations and are currently usually not included...

include the estradiol esters estradiol sulfamate (E2MATE; also a potent steroid sulfatase inhibitor) and EC508 (estradiol 17β-(1-(4-(aminosulfonyl)benzoyl)-L-proline))...

steroid sulfatase and in this way serve as precursors and circulating reservoirs for their active unsulfated counterparts. In addition, some steroid sulfates...