• Thumbnail for Tachykinin peptides
    Tachykinin peptides are one of the largest families of neuropeptides, found from amphibians to mammals. They were so named due to their ability to rapidly...
    10 KB (1,120 words) - 03:30, 26 March 2024
  • There are three known mammalian tachykinin receptors termed NK1, NK2 and NK3. All are members of the 7 transmembrane G-protein coupled receptor family...
    3 KB (148 words) - 08:42, 27 August 2022
  • Thumbnail for Tachykinin receptor 1
    The tachykinin receptor 1 (TACR1) also known as neurokinin 1 receptor (NK1R) or substance P receptor (SPR) is a G protein coupled receptor found in the...
    21 KB (2,396 words) - 04:15, 29 April 2024
  • Thumbnail for Tachykinin receptor 3
    Tachykinin receptor 3, also known as TACR3, is a protein which in humans is encoded by the TACR3 gene. This gene belongs to a family of genes that function...
    8 KB (955 words) - 23:37, 9 March 2024
  • tachykinin NK1 receptor, tachykinin NK2 receptor and tachykinin NK3 receptor. Biological research that identified the many functions of tachykinins sparked...
    29 KB (3,270 words) - 03:23, 5 December 2023
  • Thumbnail for Tachykinin receptor 2
    This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the...
    9 KB (1,178 words) - 23:36, 9 March 2024
  • Thumbnail for Substance P
    11 amino acid residues) and a type of neuropeptide, belonging to the tachykinin family of neuropeptides. It acts as a neurotransmitter and a neuromodulator...
    48 KB (5,337 words) - 03:27, 22 July 2024
  • Thumbnail for Peptide
    Peptides are short chains of amino acids linked by peptide bonds. A polypeptide is a longer, continuous, unbranched peptide chain. Polypeptides that have...
    22 KB (2,418 words) - 23:33, 30 July 2024
  • Thumbnail for Neurokinin A
    (formally known as substance K) is a member of the tachykinin family of neuropeptide neurotransmitters. Tachykinins are important contributors to nociceptive processing...
    27 KB (2,873 words) - 05:48, 13 February 2024
  • Thumbnail for Elinzanetant
    BAY-3427080 GSK-1144814, NT-814) is an orally active small-molecule neurokinin/tachykinin NK1 receptor and NK3 receptor antagonist which is under development by...
    4 KB (223 words) - 19:10, 4 January 2024
  • Thumbnail for TAC1
    Chiwakata C, Brackmann B, Hunt N, Davidoff M, Schulze W, Ivell R (May 1991). "Tachykinin (substance-P) gene expression in Leydig cells of the human and mouse testis"...
    5 KB (652 words) - 18:39, 10 January 2023
  • Thumbnail for Neurokinin B
    Neurokinin B (NKB) belongs in the family of tachykinin peptides. Neurokinin B is implicated in a variety of human functions and pathways such as the secretion...
    15 KB (1,716 words) - 22:29, 25 June 2024
  • Thumbnail for Saliva
    allows the production of more saliva. In addition, Substance P can bind to Tachykinin NK-1 receptors leading to increased intracellular calcium concentrations...
    26 KB (2,834 words) - 03:50, 25 July 2024
  • This is a list of investigational sex-hormonal agents, or sex-hormonal agents that are currently under development for clinical use but are not yet approved...
    14 KB (1,217 words) - 08:59, 1 August 2024
  • Weber HH11, one of the Hamburger–Hamilton stages in chick development Tachykinin receptor 3 (HH11) Search for "hh11"  or "hh-11" on Wikipedia. All pages...
    619 bytes (109 words) - 01:42, 4 December 2023
  • irritable bowel syndrome. Otilinium binds to both muscarinic receptors and tachykinin NK2 receptors. It has been shown to inhibit L-type and T-type calcium...
    5 KB (352 words) - 19:39, 24 June 2023
  • This is a list of signaling peptide/protein receptor modulators Agonists: Peptide: Adiponectin ADP-355 ADP-399; Non-peptide: AdipoRon (–)-Arctigenin Arctiin...
    14 KB (825 words) - 20:42, 9 February 2024
  • Thumbnail for Kassina
    species in captivity. It is the source of "kassinin", a frequently studied tachykinin peptide. Frost, Darrel R. (2016). "Kassina Girard, 1853". Amphibian Species...
    6 KB (469 words) - 21:07, 14 October 2023
  • Thumbnail for TAC4
    Tachykinin-4 is a protein that in humans is encoded by the TAC4 gene. This gene is a member of the tachykinin family of neurotransmitter-encoding genes...
    5 KB (544 words) - 19:35, 31 July 2024
  • Physalaemin is a tachykinin peptide obtained from the Physalaemus frog, closely related to substance P. Its structure was first elucidated in 1964. Like...
    5 KB (546 words) - 20:25, 13 August 2022
  • Thumbnail for Tert-Butyloxycarbonyl protecting group
    (2004). "Process Development of a Large-Scale Synthesis of TKA731: A Tachykinin Receptor Antagonist". Org. Process Res. Dev. 8 (3): 330–340. doi:10.1021/op0341824...
    10 KB (1,045 words) - 17:06, 19 July 2024
  • Thumbnail for Chromosome 17
    encoding protein Saitohin SUZ12P1 is a pseudogene TAC4: encoding protein Tachykinin-4 TBC1D3: encoding protein TBC1 domain family member 3E/3F TMEM106A: encoding...
    25 KB (1,871 words) - 19:27, 31 July 2024
  • Thumbnail for Alzheimer's disease
    "Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides". Science. 250 (4978): 279–282. Bibcode:1990Sci...250..279Y...
    179 KB (18,926 words) - 18:47, 1 August 2024
  • Thumbnail for Kassinin
    Kassinin is a peptide derived from the Kassina frog. It belongs to tachykinin family of neuropeptides. It is secreted as a defense response, and is involved...
    8 KB (920 words) - 17:31, 2 May 2023
  • Preprotachykinins are precursor proteins that are modified into tachykinin peptides. Via alternative splicing and post-translational modifications, preprotachykinins...
    1,022 bytes (112 words) - 09:59, 27 March 2024
  • Thumbnail for Burapitant
    4-piperidinyl)-2-methylpropanamide], a centrally active nonpeptide antagonist of the tachykinin neurokinin-1 receptor: I. biochemical and pharmacological characterization"...
    4 KB (294 words) - 22:18, 7 January 2024
  • Thumbnail for Pavinetant
    benefits. Tachykinin receptor 3 § Agonists "Pavinetant - Millendo Therapeutics - AdisInsight". Malherbe P, Ballard TM, Ratni H (2011). "Tachykinin neurokinin...
    4 KB (236 words) - 23:33, 5 January 2024
  • Thumbnail for TAC3
    Tachykinin-3 is a protein that in humans is encoded by the TAC3 gene. Neurokinin B Tachykinin receptor 3 GRCh38: Ensembl release 89: ENSG00000166863 –...
    8 KB (797 words) - 01:20, 4 March 2023
  • Thumbnail for Hypofrontality
    "Behavioural and Neurochemical Abnormalities in Mice Lacking Functional Tachykinin-1 (NK1) Receptors: A Model of Attention Deficit Hyperactivity Disorder"...
    20 KB (2,404 words) - 16:53, 30 April 2024
  • Thumbnail for Neurotransmitter
    Somatostatin receptors – Tachykinins Neurokinin A – – Tachykinins Neurokinin B – – Tachykinins Substance P – – Tachykinins Neuropeptide K – – Other Agouti-related...
    94 KB (8,341 words) - 07:25, 27 July 2024