Telomeric repeat-binding factor 2 is a protein that is present at telomeres throughout the cell cycle. It is also known as TERF2, TRF2, and TRBF2, and...
27 KB (3,340 words) - 22:06, 22 December 2023
Telomeric repeat-binding factor 1 is a protein that in humans is encoded by the TERF1 gene. The human TERF1 gene is located in the chromosome 8 at 73...
20 KB (2,474 words) - 11:36, 23 December 2023
Telomeric repeat–containing RNA (TERRA) is a long non-coding RNA transcribed from telomeres - repetitive nucleotide regions found on the ends of chromosomes...
35 KB (4,668 words) - 11:25, 11 February 2024
Telomeric repeat-binding factor 2-interacting protein 1 also known as repressor activator protein 1 (Rap1) is a protein that in humans is encoded by the...
9 KB (1,161 words) - 18:14, 7 August 2022
telomere-binding protein refers to TTAGGG repeat binding factor-1 (TERF1) and TTAGGG repeat binding factor-2 (TERF2). Telomere sequences in humans are...
13 KB (1,658 words) - 08:34, 4 December 2022
Microsatellite (redirect from Short tandem repeat)
replication problem". In white blood cells, the gradual shortening of telomeric DNA has been shown to inversely correlate with ageing in several sample...
67 KB (7,394 words) - 16:46, 2 September 2024
Long non-coding RNA (redirect from Telomeric non-coding RNAs)
Khoriauli L, Giulotto E, Lingner J (November 2007). "Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends". Science. 318 (5851):...
121 KB (13,137 words) - 03:37, 18 November 2024
G-quadruplex (section Telomeric quadruplexes)
Dash D, Chowdhury S (November 2019). "Telomere Repeat-Binding Factor 2 Binds Extensively to Extra-Telomeric G-quadruplexes and Regulates the Epigenetic Status...
94 KB (11,911 words) - 03:22, 31 October 2024
human telomeric DNA in vitro. Beyond nucleic acid binding, FUS/TLS was also found to associate with both general and more specialized protein factors to...
32 KB (3,968 words) - 22:39, 23 September 2024
PMID 31072070. Cusanelli E, Chartrand P (May 2014). "Telomeric noncoding RNA: telomeric repeat-containing RNA in telomere biology". Wiley Interdisciplinary...
42 KB (4,774 words) - 17:56, 3 November 2024
Shelterin (category Telomere-binding proteins)
about ten times more abundant than TPP1 and POT1. TRF1 (Telomere Repeat binding Factor 1): TRF1 is a homodimeric protein that binds to the double-stranded...
21 KB (2,334 words) - 22:04, 20 September 2024
(August 2010). "The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1". PLOS ONE. 5 (8): e12407. Bibcode:2010PLoSO...
20 KB (1,947 words) - 11:18, 21 May 2024
present, telomeric to the D4Z4 repeat array. The open reading frame (ORF) is entirely contained within exon 1 and contains two homeoboxes. Exons 2 and 3...
7 KB (706 words) - 19:30, 22 July 2024
S (2002). "The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a...
7 KB (822 words) - 06:18, 5 January 2024
single stranded 3' end of the template DNA and contains 1.5 copies of the telomeric sequence. Telomerase contains a protein subunit that is a reverse transcriptase...
119 KB (14,646 words) - 22:02, 3 July 2024
possible as a result of the telomeric repeats found within the direct repeat termini of HHV-6's genome. The right direct repeat terminus integrates within...
78 KB (8,112 words) - 16:36, 5 July 2024
Subsequently, direct binding to telomeric DNA was demonstrated through a co-crystal structure of the DNA-binding domain of HMBOX1 with telomeric DNA. Loss-of-function...
4 KB (452 words) - 01:09, 9 April 2022
1 encodes for DUX4 protein. Exon 3 is in the pLAM region telomeric to the last partial repeat, and it can vary in length depending on the type of 4qA allele...
176 KB (16,456 words) - 00:30, 6 November 2024
(Apr 2002). "The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a...
12 KB (1,493 words) - 17:10, 2 December 2023
associated with 40S ribosomal subunits, translation initiation factors, poly(A)+ mRNA and RNA-binding proteins (RBPs). While they are membraneless organelles...
183 KB (12,460 words) - 13:46, 23 September 2024
(Apr 2002). "The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a...
6 KB (663 words) - 00:53, 4 March 2023
inhibitory effect by binding to telomeric DNA. In the Late S/G2 phase, the protein kinase CDK1 (cyclin-dependent) promotes telomeric resection. This control...
18 KB (2,277 words) - 13:23, 26 November 2023
1, telomeric SMN2: survival motor neuron 2, centromeric SNCAIP: synuclein, alpha interacting protein (synphilin) SPEF2: Sperm flagellar protein 2 SPINK5:...
32 KB (2,298 words) - 22:55, 28 March 2024
MeSH D12.776.660.235.700.750 – telomeric repeat binding protein 1 MeSH D12.776.660.235.700.875 – telomeric repeat binding protein 2 MeSH D12.776.660.352.500...
9 KB (356 words) - 16:49, 9 February 2024
ISBN 978-3-319-21755-0. PMID 26860303. Sundquist WI, Klug A (December 1989). "Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops"....
11 KB (1,202 words) - 06:34, 26 April 2024
mating type loci and at yeast telomeres, the transcription factors Abf1 (ARS binding factor) and Rap1 (repressor-activator protein) associate with specific...
19 KB (2,343 words) - 01:04, 3 December 2023
single-stranded DNA binding proteins (SSB). In the replication machineries these components coordinate. In most of the bacteria, all of the factors involved in...
60 KB (7,286 words) - 00:09, 20 November 2024
Telomerase (category EC 2.7.7)
Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA. Nat Struct Mol Biol. 2010 Apr;17(4):513-8 NCBI - telomerase...
49 KB (5,697 words) - 14:29, 22 November 2024
Cortactin (section Activation and binding)
in breast and squamous cell carcinomas encompasses three CpG islands telomeric of FGF3, including the expressed gene EMS1". Genes Chromosomes Cancer...
21 KB (2,576 words) - 11:30, 27 March 2024