Trk receptors are a family of tyrosine kinases that regulates synaptic strength and plasticity in the mammalian nervous system. Trk receptors affect neuronal...
27 KB (3,122 words) - 21:45, 8 July 2024
Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type...
40 KB (4,319 words) - 02:54, 11 August 2024
Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming...
27 KB (3,264 words) - 05:43, 13 April 2024
Indonesia Potassium transport proteins (Trk), a constituent of the protein family bacterial potassium transporter Trk receptor, a family of tyrosine kinases that...
633 bytes (116 words) - 17:00, 18 April 2024
Tropomyosin receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, or TrkC tyrosine kinase...
32 KB (3,936 words) - 03:00, 29 January 2024
Brain-derived neurotrophic factor (category TrkB agonists)
activates the TrkB tyrosine kinase receptor. BDNF acts on certain neurons of the central nervous system and the peripheral nervous system expressing TrkB, helping...
46 KB (5,344 words) - 03:26, 11 August 2024
Nerve growth factor (redirect from Receptor, nerve growth factor)
TrkA receptor facilitates receptor dimerization and tyrosine residue phosphorylation of the cytoplasmic tail by adjacent Trk receptors. Trk receptor phosphorylation...
24 KB (2,872 words) - 06:27, 22 July 2024
neurotrophic factor receptors are the p75 and the "Trk" families of Tyrosine kinases receptors. p75 is a low affinity neurotrophin receptor, to which all neurotrophins...
5 KB (670 words) - 17:28, 23 January 2021
Neurotrophin-3 (category TrkB agonists)
stimulate, given its ability to activate two of the receptor tyrosine kinase neurotrophin receptors (TrkC and TrkB). Mice born without the ability to make NT-3...
14 KB (1,816 words) - 04:39, 31 October 2023
Neurotrophin (section Receptors)
stimulate, given its ability to activate two of the receptor tyrosine kinase neurotrophin receptors (TrkC and TrkB). Mice born without the ability to make NT-3...
27 KB (3,071 words) - 04:54, 3 June 2024
TrkA. p75NTR activation of NF-kB, which promotes survival, is unaffected by NGF binding to TrkA. p75NTR functions in a complex with Nogo-66 receptor (NgR1)...
37 KB (4,235 words) - 13:48, 29 June 2024
Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90...
28 KB (3,078 words) - 07:46, 3 June 2024
interacting with the extracellular region of tropomyosin receptor kinase, or Trk, receptors. Trk receptors are crucial to the survival and development of sensory...
40 KB (4,422 words) - 19:52, 23 August 2024
Adenosine (category Adenosine receptor agonists)
adenosine agonists can activate Trk receptor phosphorylation through a mechanism that requires the adenosine A2A receptor. Adenosine has been shown to promote...
32 KB (3,346 words) - 01:19, 26 August 2024
Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. They...
9 KB (974 words) - 14:46, 22 June 2024
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth...
60 KB (6,879 words) - 14:26, 16 July 2024
HER2 (redirect from ErbB-2 receptor)
Receptor tyrosine-protein kinase erbB-2 is a protein that normally resides in the membranes of cells and is encoded by the ERBB2 gene. ERBB is abbreviated...
43 KB (4,651 words) - 13:41, 27 July 2024
The insulin receptor (IR) is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of receptor tyrosine kinase...
31 KB (3,785 words) - 19:26, 2 September 2024
for angiotensin receptors, although their exact role is still unclear. The action of AII itself is targeted by angiotensin II receptor antagonists, which...
28 KB (3,125 words) - 22:38, 10 August 2024
VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending...
8 KB (755 words) - 18:51, 2 November 2023
The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
8 KB (827 words) - 22:08, 3 December 2023
A metabotropic receptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic...
6 KB (625 words) - 00:59, 6 June 2024
Nalfurafine (redirect from TRK-820)
Nalfurafine (INN, USAN) (brand name Remitch; former developmental code names TRK-820, AC-820, MT-9938) is an antipruritic (anti-itch drug) that is marketed...
16 KB (1,282 words) - 21:59, 16 May 2024
Tyrosine kinase (section Receptor)
factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), stem cell factor receptor, and colony-stimulating factor-1 receptor (Burstein...
43 KB (5,251 words) - 10:44, 24 June 2024
development as it is required for transmitting signals from the pre-B cell receptor that forms after successful immunoglobulin heavy chain rearrangement. It...
22 KB (2,389 words) - 06:43, 22 April 2024
Src kinase family is a family of non-receptor tyrosine kinases that includes nine members: Src, Yes, Fyn, and Fgr, forming the SrcA subfamily, Lck, Hck...
10 KB (1,215 words) - 03:15, 19 April 2024
antiangiogenic properties. A non-membrane associated splice variant of VEGF receptor 1 (Flt-1), sFlt-1 binds the angiogenic factors VEGF (vascular endothelial...
19 KB (2,341 words) - 00:54, 8 November 2023
KIT (gene) (redirect from C-kit receptor)
Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase protein known as tyrosine-protein kinase KIT, CD117 (cluster of differentiation...
35 KB (4,117 words) - 00:12, 6 August 2024
Tyrosine-protein kinase receptor UFO is a protein that in human is encoded by the AXL gene. The gene was initially designated as UFO, in allusion to the...
19 KB (2,358 words) - 16:34, 16 July 2024
interferon receptors), the GM-CSF receptor family (IL-3R, IL-5R and GM-CSF-R), the gp130 receptor family (e.g., IL-6R), and the single chain receptors (e.g...
28 KB (3,166 words) - 19:57, 8 August 2024