• Thumbnail for Vincristine
    Vincristine, also known as leurocristine and marketed under the brand name Oncovin among others, is a chemotherapy medication used to treat a number of...
    31 KB (2,832 words) - 13:30, 20 September 2024
  • Thumbnail for Catharanthus roseus
    and now has a pantropical distribution. It is a source of the drugs vincristine and vinblastine, used to treat cancer. It was formerly included in the...
    27 KB (2,647 words) - 19:29, 6 October 2024
  • Thumbnail for Dysautonomia
    multiple system atrophy Surgery or injury involving the nerves Toxicity (vincristine) In the sympathetic nervous system (SNS), predominant dysautonomia is...
    28 KB (2,665 words) - 06:16, 10 July 2024
  • cyclophosphamide, vincristine (Oncovin), dexamethasone Non-Hodgkin lymphomas BEACOPP bleomycin, etoposide, doxorubicin (Adriamycin), cyclophosphamide, vincristine (Oncovin)...
    23 KB (634 words) - 23:47, 16 August 2024
  • Thumbnail for Vinca
    is a chemical analogue of vincristine and is also used to treat various forms of cancer. Dimeric alkaloids such as vincristine and vinblastine are produced...
    16 KB (1,327 words) - 18:38, 5 January 2024
  • Thumbnail for Intrathecal administration
    hydrocortisone, and thiotepa. Administration of any vinca alkaloids, especially vincristine, via the intrathecal route is nearly always fatal. Often reserved for...
    9 KB (979 words) - 03:03, 16 September 2024
  • Thumbnail for Chemotherapy
    microtubules. The original vinca alkaloids are natural products that include vincristine and vinblastine. Following the success of these drugs, semi-synthetic...
    155 KB (17,546 words) - 16:49, 16 August 2024
  • Thumbnail for Spermatogonium
    become primary spermatocytes. Anticancer drugs such as doxorubicin and vincristine can adversely affect male fertility by damaging the DNA of proliferative...
    3 KB (292 words) - 17:35, 23 August 2023
  • Thumbnail for Dimerization of catharanthine and vindoline
    roseus) whose dimerization produces the anti-cancer drugs vinblastine and vincristine. The precursor of catharanthine and vindoline is strictosidine, the common...
    8 KB (1,063 words) - 12:49, 12 September 2024
  • example, the CHOP regimen consists of cyclophosphamide, doxorubicin, vincristine and prednisone. Besides chemotherapy, medical oncology (pharmacotherapy...
    5 KB (324 words) - 12:07, 20 July 2024
  • Thumbnail for Bortezomib
    potentially help recover from vincristine treatment in treating acute lymphoblastic leukemia, when replacing vincristine in the process. Bortezomib was...
    24 KB (2,260 words) - 18:03, 5 October 2024
  • Thumbnail for Vinblastine
    administration. Vinblastine is a vinca alkaloid and a chemical analogue of vincristine. It binds tubulin, thereby inhibiting the assembly of microtubules. Vinblastine...
    19 KB (1,703 words) - 05:39, 9 August 2024
  • Thumbnail for Catharanthus
    plant produces about 130 of these compounds, including vinblastine and vincristine, two drugs used to treat cancer. Catharanthus roseus is also cultivated...
    5 KB (459 words) - 20:27, 14 October 2023
  • Thumbnail for Vinca alkaloid
    produces from them: leurosine and the chemotherapy agents vinblastine and vincristine, all of which can be obtained from the plant. The newer semi-synthetic...
    10 KB (934 words) - 10:47, 16 August 2023
  • Thumbnail for Leukemia
    (cyclophosphamide, doxorubicin, vincristine, prednisone CHOP, cyclophosphamide, vincristine, prednisone [COP], vincristine, doxorubicin, prednisone, etoposide...
    83 KB (8,161 words) - 00:29, 7 October 2024
  • Thumbnail for Plant
    aspirin, taxol, morphine, quinine, reserpine, colchicine, digitalis and vincristine. Plants used in herbalism include ginkgo, echinacea, feverfew, and Saint...
    95 KB (8,057 words) - 17:06, 22 September 2024
  • Thumbnail for Dactinomycin
    with other drugs in chemotherapy regimens, like the VAC regimen (with vincristine and cyclophosphamide) for treating rhabdomyosarcoma and Ewing's sarcoma...
    20 KB (1,865 words) - 04:30, 3 January 2024
  • Thumbnail for Mitotic inhibitor
    the treatment of cancer include paclitaxel, docetaxel, vinblastine, vincristine, and vinorelbine. Colchicine and griseofulvin are mitotic inhibitors...
    59 KB (6,992 words) - 22:40, 13 August 2024
  • Thumbnail for Anakinra
    chemotherapy with vincristine, saying that "repurposing anakinra may be an effective co-treatment strategy to prevent vincristine-induced peripheral...
    24 KB (2,070 words) - 07:13, 15 March 2024
  • Thumbnail for Emtricitabine/tenofovir
    effect of emtricitabine. Vincristine used with P-glycoprotein/ABCB1 inducers can decrease the serum concentration of vincristine. The patent for the drug...
    29 KB (2,371 words) - 04:11, 19 August 2024
  • Thumbnail for History of cancer chemotherapy
    of tumour cells. The antitumour effect of the vinca alkaloids (e.g. vincristine) was later shown to be due to their ability to inhibit microtubule polymerization...
    31 KB (3,824 words) - 20:24, 15 August 2024
  • Thumbnail for Medicinal plants
    serpentina), quinidine and quinine (Cinchona), vincamine (Vinca minor), and vincristine (Catharanthus roseus). The opium poppy Papaver somniferum is the source...
    81 KB (8,315 words) - 12:45, 1 October 2024
  • Thumbnail for Prince of Wales Hospital
    erroneously injected a leukaemia patient with the chemotherapy drug, vincristine, via the intrathecal route instead of intravenous on 15 June 2007. The...
    32 KB (3,300 words) - 18:25, 20 March 2024
  • Thumbnail for CHOP (chemotherapy)
    agent which damages DNA by inserting itself between DNA bases Oncovin (vincristine), which prevents cells from duplicating by binding to the protein tubulin...
    12 KB (1,017 words) - 19:41, 26 July 2024
  • Thumbnail for Choriocarcinoma
    EMACO (etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine (Oncovin) are recommended for intermediate or high-risk disease. Hysterectomy...
    9 KB (894 words) - 05:42, 5 July 2024
  • Thumbnail for Madagascar
    herbal remedies for a variety of afflictions. The drugs vinblastine and vincristine are vinca alkaloids, used to treat Hodgkin lymphoma, leukemia, and other...
    225 KB (21,048 words) - 13:03, 29 September 2024
  • Thumbnail for Procarbazine
    chlormethine, vincristine, and prednisone while for brain cancers such as glioblastoma multiforme it is used with lomustine and vincristine. It is typically...
    11 KB (821 words) - 05:21, 7 June 2023
  • lysis of both normal and malignant lymphocytes; Oncovin, also known as vincristine: a vinca alkaloid that binds to the protein tubulin, thereby preventing...
    6 KB (684 words) - 09:38, 30 September 2022
  • US FDA approves vincristine (Oncovin) for chemotherapy of cancer 1964  – VAMP regimen combination therapy, consisting of: vincristine, amethopterin, 6-mercaptopurine...
    27 KB (2,580 words) - 18:15, 7 September 2023
  • Thumbnail for Canine transmissible venereal tumor
    been identified. The tumor, when treated with the chemotherapy drug vincristine, regresses as the host immune system is activated. CCL5 may play an important...
    15 KB (1,748 words) - 19:33, 5 September 2024