12-Hydroxyheptadecatrienoic acid (also termed 12-HHT, 12(S)-hydroxyheptadeca-5Z,8E,10E-trienoic acid, or 12(S)-HHTrE) is a 17 carbon metabolite of the...
32 KB (3,734 words) - 09:00, 24 January 2024
liver, and ovary. However, 12-Hydroxyheptadecatrienoic acid (i.e. 12-(S)-hydroxy-5Z,8E,10E-heptadecatrienoic acid or 12-HHT), a product made when prostaglandin...
63 KB (6,987 words) - 10:03, 27 March 2024
of 12-(S)-hydroxy-5Z,8E,10E-heptadecatrienoic acid (HHT) and 12-(S)-hydroxy-5Z,8Z,10E-heptadecatrienoic acid (see 12-hydroxyheptadecatrienoic acid) Functions...
6 KB (505 words) - 01:38, 1 March 2024
prostaglandin G2/H2, 12-hydroxyheptadecatrienoic acid (12-HHT). The enzyme 5-lipoxygenase catalyzes the oxidation of arachidonic acid to 5-hydroperoxyeicosatetraenoic...
21 KB (1,900 words) - 21:15, 28 July 2024
8-cis and 8-trans isomers of 12-hydroxyeicosaheptaenoic acid plus malonyldialdehyde (see 12-Hydroxyheptadecatrienoic acid). The degree of lipid peroxidation...
9 KB (930 words) - 01:17, 16 July 2024
reaction which generates approximately equal amounts of 12-Hydroxyheptadecatrienoic acid (12-HHT). Aspirin irreversibly inhibits platelet cyclooxygenase...
7 KB (712 words) - 06:11, 11 February 2024
non-enzymatically to a mixture of 12-Hydroxyheptadecatrienoic acids viz.,1 2-(S)-hydroxy-5Z,8E,10E-heptadecatrienoic acid (i.e. 12-HHT) and 12-(S)-hydroxy-5Z,8Z,10E-heptadecatrienoic...
18 KB (2,122 words) - 12:15, 2 June 2024
Epoxygenase (section Arachidonic acid)
arachidonic acid (and other polyunsaturated fatty acids), CYP2S1 metabolizes prostaglandin G2 and Prostaglandin H2 to 12-Hydroxyheptadecatrienoic acid. Possibly...
41 KB (4,771 words) - 12:28, 14 June 2024
arachidonic acid metabolites, one of which, 12-hydroxyheptadecatrienoic acid (12-HHT), has 10- to 100-fold higher affinity for it than does LTB4; 12-HHT fails...
50 KB (6,792 words) - 02:25, 22 June 2024
needed][non-primary source needed] 12-Hydroxyheptadecatrienoic acid is a non-eicosanoid metabolite of arachidonic acid made by cyclooxygenase 1 or cyclooxygenase...
65 KB (7,370 words) - 06:10, 19 July 2024
platelet aggregation, and also to 12-Hydroxyheptadecatrienoic acid (i.e. 12-(S)-hydroxy-5Z,8E,10E-heptadecatrienoic acid or 12-HHT) an agonist of Leukotriene...
19 KB (2,231 words) - 04:04, 8 February 2024
ALOX12 (redirect from Arachidonate 12-lipoxygenase)
metabolize arachidonic acid not only by the well-known cyclooxygenase pathway into prostaglandins and 12-hydroxyheptadecatrienoic acid but also by a...
32 KB (3,928 words) - 09:06, 1 September 2023
are: 12-hydroxyheptadecatrienoic acid (S isomer)>leukotriene B4>12-Hydroxyeicosatetraenoic acid (S isomer)= 12-hydroperoxyeicosatetraenoic acid (S...
24 KB (2,893 words) - 07:17, 15 May 2024
biologically active product, 12-Hydroxyheptadecatrienoic acid (i.e. 12(S)-hydroxyheptadeca-5Z,8E,10E-trienoic acid, also termed 12-HHT). GRCh38: Ensembl release...
10 KB (1,322 words) - 05:09, 2 May 2024