• Thumbnail for 17α-Hydroxyprogesterone
    17α-Hydroxyprogesterone (17α-OHP), also known as 17-OH progesterone (17-OHP), or hydroxyprogesterone (OHP), is an endogenous progestogen steroid hormone...
    14 KB (1,126 words) - 10:08, 7 July 2024
  • Thumbnail for Hydroxyprogesterone caproate
    treatment of preterm birth in 2011 until the FDA banned 17α-OHPC in 2023. The use of hydroxyprogesterone caproate in pregnancy to prevent preterm birth in women...
    121 KB (12,026 words) - 08:48, 2 November 2024
  • Thumbnail for Medroxyprogesterone
    contraction of 6α-methyl-17α-hydroxyprogesterone. It is closely related to medrogestone as well as other unesterified 17α-hydroxyprogesterone derivatives such as...
    7 KB (482 words) - 04:13, 23 October 2024
  • Thumbnail for Hydroxyprogesterone acetate
    has more than 50-fold higher affinity for the PR isoforms than 17α-hydroxyprogesterone, a little less than half the affinity of progesterone, and slightly...
    26 KB (3,336 words) - 21:46, 22 August 2024
  • Thumbnail for Medroxyprogesterone acetate
    6α-methyl-17α-acetoxyprogesterone or as 6α-methyl-17α-acetoxypregn-4-ene-3,20-dione, and its generic name is a contraction of 6α-methyl-17α-hydroxyprogesterone...
    177 KB (18,939 words) - 06:32, 22 December 2024
  • Thumbnail for Progestogen ester
    include the 17α-hydroxyprogesterone derivatives medroxyprogesterone acetate, megestrol acetate, cyproterone acetate, and hydroxyprogesterone caproate, the...
    22 KB (2,387 words) - 00:35, 9 December 2023
  • Thumbnail for List of progestogen esters
    progestogen esters, with the exception of esters of 17α-hydroxyprogesterone like hydroxyprogesterone caproate, are esters of progestins (synthetic progestogens)...
    9 KB (834 words) - 17:43, 20 February 2024
  • Thumbnail for Progestogen (medication)
    being the testosterone derivatives and, to a lesser extent, the 17α-hydroxyprogesterone derivatives medroxyprogesterone acetate and megestrol acetate....
    176 KB (18,555 words) - 06:07, 16 November 2024
  • Thumbnail for Steroid
    by adding prefixes only rather than suffixes, e.g., the steroid 17α-hydroxyprogesterone has a hydroxy group (-OH) at position 17 of the steroid nucleus...
    83 KB (8,523 words) - 03:41, 25 November 2024
  • Thumbnail for Triamcinolone acetonide
    also known as 9α-fluoro-16α-hydroxyprednisolone 16α,17α-acetonide or as 9α-fluoro-11β,16α-17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal...
    16 KB (1,220 words) - 14:16, 5 September 2024
  • Thumbnail for Spironolactone
    hydroxyl group has been substituted at the C17α position (as in 17α-hydroxyprogesterone), the acetyl group at the C17β position has been cyclized with...
    181 KB (17,377 words) - 22:04, 17 December 2024
  • Thumbnail for Progesterone
    hydroxylated via 17α-hydroxylase (CYP17A1) and 21-hydroxylase (CYP21A2) into 17α-hydroxyprogesterone and 11-deoxycorticosterone (21-hydroxyprogesterone), respectively...
    123 KB (11,583 words) - 02:59, 21 December 2024
  • Thumbnail for CYP17A1
    CYP17A1 (redirect from 17α-hydroxylase)
    (C17) of the steroid D ring (the 17α-hydroxylase activity, EC 1.14.14.19), or acts upon 17α-hydroxyprogesterone and 17α-hydroxypregnenolone to split the...
    24 KB (2,696 words) - 04:11, 13 August 2024
  • Thumbnail for Congenital adrenal hyperplasia
    hypoaldosteronism) Elevated 17α-hydroxyprogesterone Classic 21-hydroxylase deficiency typically causes 17α-hydroxyprogesterone blood levels >242 nmol/L.[medical...
    43 KB (4,344 words) - 07:26, 16 December 2024
  • Thumbnail for Hydroxyprogesterone heptanoate
    hydroxyprogesterone enanthate (OHPE), as well as 17α-hydroxyprogesterone heptanoate or 17α-hydroxypregn-4-ene-3,20-dione 17α-heptanoate, is a synthetic pregnane steroid...
    17 KB (1,285 words) - 16:49, 8 June 2024
  • Thumbnail for Progestogen
    are used in medicine. Major examples of progestins include the 17α-hydroxyprogesterone derivative medroxyprogesterone acetate and the 19-nortestosterone...
    16 KB (1,567 words) - 01:04, 8 October 2024
  • Thumbnail for Dihydrotestosterone
    testosterone. DHT may also be synthesized from progesterone and 17α-hydroxyprogesterone via the androgen backdoor pathway in the absence of testosterone...
    67 KB (6,840 words) - 00:18, 4 November 2024
  • Thumbnail for 16α-Hydroxyprogesterone
    metabolite of progesterone that is formed in lower amounts than 17α-hydroxyprogesterone (17α-OHP). It occurs in micromolar concentrations and its physiological...
    4 KB (341 words) - 20:53, 22 December 2023
  • Thumbnail for Megestrol acetate
    other 17α-hydroxyprogesterone derivatives such as acetomepregenol, anagestone acetate, chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate...
    108 KB (11,654 words) - 08:32, 16 May 2024
  • Thumbnail for Dydrogesterone
    Gynaecology and Obstetrics. de Gruyter. p. 49. ISBN 9783110006148. 17α-Hydroxyprogesterone caproate is a depot progestogen which is entirely free of side...
    61 KB (6,712 words) - 07:01, 27 October 2024
  • Thumbnail for 5α-Pregnan-17α-ol-3,20-dione
    5α-Pregnan-17α-ol-3,20-dione, also known as 17α-hydroxy-dihydroprogesterone (17-OH-DHP) is an endogenous steroid, a metabolite of 17α-hydroxyprogesterone. 5α-Pregnan-17α-ol-3...
    11 KB (1,041 words) - 08:11, 20 August 2024
  • Thumbnail for 17α-Hydroxypregnenolone
    pregnenolone to DHEA. 17α-Hydroxypregneolone is also converted to 17α-hydroxyprogesterone, a prohormone for glucocorticosteroids and androstenedione through...
    5 KB (360 words) - 19:10, 8 March 2023
  • Thumbnail for List of progestogens
    progestogen, retroprogesterone is not medically used. Note that 17α-hydroxyprogesterone is inactive as a progestogen and is not used medically. The 19-norprogesterone...
    13 KB (270 words) - 12:57, 12 October 2022
  • Thumbnail for Sex hormone
    Progesterone → Allopregnanedione → Allopregnanolone 17α-Hydroxypregnenolone → 17α-Hydroxyprogesterone Androgens Dehydroepiandrosterone → Androstenedione...
    7 KB (587 words) - 14:40, 2 November 2024
  • Thumbnail for Gestonorone acetate
    and 17α-hydroxyprogesterone groups which was developed in the early 1960s but was never marketed. It is the C17α acetate ester of gestronol (17α...
    8 KB (670 words) - 20:59, 9 December 2023
  • As 17α-hydroxylase it mediates pregnenolone → 17α-hydroxypregnenolone and progesterone → 17α-hydroxyprogesterone. As 17,20-lyase it mediates 17α-hydroxypregnenolone...
    16 KB (1,830 words) - 22:53, 22 April 2024
  • Thumbnail for Ketoconazole
    significantly increase luteinizing hormone, progesterone, and 17α-hydroxyprogesterone levels, whereas levels of androstenedione, follicle-stimulating...
    50 KB (4,376 words) - 23:55, 20 December 2024
  • Thumbnail for Estradiol valerate/hydroxyprogesterone caproate
    Estradiol valerate/hydroxyprogesterone caproate (EV/OHPC), sold under the brand names Gravibinon and Injectable No. 1 (or Chinese Injectable No. 1) among...
    19 KB (1,697 words) - 20:00, 16 March 2024
  • Thumbnail for Trenbolone
    Retroprogesterone derivatives: Dydrogesterone Trengestone 17α-Hydroxyprogesterone (and closely related) derivatives: 17α-Hydroxylated: Acetomepregenol (mepregenol diacetate)...
    23 KB (1,906 words) - 14:31, 24 November 2024
  • Thumbnail for List of corticosteroids
    [1] 11β-Hydroxyprogesterone (21-deoxycorticosterone) = 11β-hydroxypregn-4-ene-3,20-dione 11β,17α,21-Trihydroxypregnenolone = 3β,11β,17α...
    11 KB (1,237 words) - 00:17, 3 December 2023