Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. It is responsible for the distribution of melanin pigment in mammals...
27 KB (3,257 words) - 21:56, 17 August 2024
The agouti gene, the Agouti-signaling protein (ASIP) is responsible for variations in color in many species. Agouti works with extension to regulate the...
29 KB (2,881 words) - 05:42, 20 June 2024
pseudoagouti. Agouti, an animal of order Rodentia it was named after Agouti-signaling protein, the protein encoded by the agouti (ASIP) gene Agouti coloration...
4 KB (485 words) - 05:46, 22 September 2024
Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. It is synthesized in...
24 KB (2,767 words) - 05:59, 16 July 2024
molecule called the agouti-signaling protein, or ASIP. This molecule interacts with MC1R, the receptor coded by extension, to block the signal for black pigment...
51 KB (4,824 words) - 10:35, 7 September 2024
Cat coat genetics (section Agouti)
the hair shaft. The Agouti gene, with its dominant A allele and recessive a allele, controls the coding for agouti signaling protein (ASIP; Q865F0). The...
57 KB (6,371 words) - 00:59, 2 October 2024
among Holland Lops, produces a dark orange color known as ASIP or Agouti Signaling Protein. This color is distinct from the normal light orange color. The...
17 KB (2,107 words) - 01:23, 3 September 2024
Dog coat genetics (section A (agouti) locus)
Ekenstedt, Kari J. (3 July 2020). "Atypical Genotypes for Canine Agouti Signaling Protein Suggest Novel Chromosomal Rearrangement". Genes. 11 (7): 739. doi:10...
82 KB (9,470 words) - 01:12, 19 August 2024
residue at position 126 of Agouti-signaling protein. This disrupts one of the four disulphide bonds in the normal protein, altering its tertiary structure...
14 KB (1,428 words) - 06:11, 19 April 2024
absence is mediated by agouti signalling protein, which antagonizes melanocortin 1 receptor. Loss of function of agouti signalling protein can permit unmediated...
14 KB (1,537 words) - 21:02, 20 September 2023
western population of fox squirrels and by a point mutation in the agouti-signaling protein gene in the southeastern population. Black morphs may also occur...
40 KB (4,495 words) - 07:31, 27 September 2024
Cuniculus, formerly Agouti Agouti (coloration), fur coloration in which each hair has alternating dark and light bands Agouti-signalling protein or ASIP, a circulating...
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mutation in ASIP (agouti signaling protein) had a higher incidence of melanoma, implying that increased melanocortin-1 receptor signaling promotes melanoma...
24 KB (2,455 words) - 04:45, 22 January 2024
Melanocortin 4 receptor (category G protein-coupled receptors)
Yamada T, Barsh GS, Gantz I (March 1997). "Effects of recombinant agouti-signaling protein on melanocortin action". Molecular Endocrinology. 11 (3): 274–80...
33 KB (3,164 words) - 08:06, 10 March 2024
Shriver, M. D.; Kittles, R. A. (2005). "The 8818G allele of the agouti signaling protein (ASIP) gene is ancestral and is associated with darker skin color...
129 KB (14,413 words) - 19:17, 7 October 2024
adrenocorticotropic hormone are endogenous agonists of MC1R.: 1175 Agouti signaling protein (ASIP) appears to be the only endogenous antagonist of MC1R. Synthetic...
67 KB (7,644 words) - 13:03, 4 October 2024
Legrand, Romain; Tiret, Laurent (2015). "A missense mutation in the agouti signaling protein gene (ASIP) is associated with the no light points coat phenotype...
5 KB (478 words) - 04:20, 12 October 2024
cysteine residue at position 120 of Agouti-signaling protein. This disrupts the four disulphide bonds in the normal protein, altering its tertiary structure...
20 KB (2,174 words) - 04:57, 25 June 2024
Proopiomelanocortin (category Protein pages needing a picture)
Yamada T, Barsh GS, et al. (March 1997). "Effects of recombinant agouti-signaling protein on melanocortin action". Molecular Endocrinology. 11 (3): 274–80...
20 KB (2,226 words) - 03:59, 25 September 2024
1 receptor and the Agouti locus as being the cause of the black dilution trait in dogs. Instead, TYRP1 (tyrosinase related protein 1) was found to be...
24 KB (3,101 words) - 15:57, 30 March 2024
Lamoreux ML, Wilson BD, Barsh GS (February 1998). "Interaction of Agouti protein with the melanocortin 1 receptor in vitro and in vivo". Genes & Development...
11 KB (1,120 words) - 05:43, 29 February 2024
stimulated by α-melanocortin stimulating hormone but inhibited by agouti signal protein. The fact that OA1 responds to melanin modifiers indicates its probable...
23 KB (2,869 words) - 00:39, 9 September 2024
ACTH receptor (category G protein-coupled receptors)
suggests that there is more protein-related specificity for binding MC2R. Agouti-related protein and Agouti-signaling protein are antagonist peptides to...
20 KB (2,316 words) - 22:00, 18 March 2024
Homologous recombination (section Protein engineering)
AF, Reddy M, Smith GR (December 2007). "Intersubunit signaling in RecBCD enzyme, a complex protein machine regulated by Chi hot spots". Genes & Development...
106 KB (12,117 words) - 07:58, 5 October 2024
Inhibitor cystine knot (category Protein structure)
and targeting agents for chemotherapy. The mammalian proteins Agouti signalling peptide and Agouti related peptide are the only known mammalian examples...
6 KB (643 words) - 16:00, 30 March 2024
neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a synapse. The cell receiving the signal, or target cell, may...
94 KB (8,341 words) - 08:44, 9 August 2024
depolarization of the cell. Compared to classical neurotransmitter signaling, neuropeptide signaling is more sensitive. Neuropeptide receptor affinity is in the...
21 KB (2,317 words) - 13:08, 8 July 2024
Melanocyte-stimulating hormone (category Protein pages needing a picture)
express MC3 and MC4 receptors. Melanocyte-inhibiting factor Agouti-related peptide Agouti signalling peptide Nelson's syndrome Katzung, Bertram G.; Masters...
10 KB (940 words) - 05:25, 31 October 2023
metabotropic, G-protein coupled receptors (GPCRs) to initiate a second messenger signaling cascade that induces a broad, long-lasting signal. This modulation...
33 KB (3,070 words) - 04:59, 28 July 2024
genistein (250 mg/kg) have epigenetic changes affecting expression of the agouti gene, which affects their fur color, weight, and propensity to develop cancer...
161 KB (18,346 words) - 02:11, 20 August 2024