An angiogenesis inhibitor is a substance that inhibits the growth of new blood vessels (angiogenesis). Some angiogenesis inhibitors are endogenous and...

Angiogenesis continues the growth of the vasculature mainly by processes of sprouting and splitting, but processes such as coalescent angiogenesis, vessel...

include: Brain-specific angiogenesis inhibitor 1 Brain-specific angiogenesis inhibitor 2 Brain-specific angiogenesis inhibitor 3 Shiratsuchi T, Nishimori H,...

secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas. Brain-specific angiogenesis inhibitor 1 has been shown to interact...

Brain-specific angiogenesis inhibitor 2 is a protein that in humans is encoded by the BAI2 gene. It is a member of the adhesion-GPCR family of receptors...

Brain-specific angiogenesis inhibitor 3 is a protein that in humans is encoded by the BAI3 gene. BAI1, a p53-target gene, encodes brain-specific angiogenesis inhibitor...

A cartilage-derived angiogenesis inhibitor is an angiogenesis inhibitor produced from cartilage. Examples include the peptide troponin I and chondromodulin...

angiogenesis, the process by which a tumor attracts blood vessels to nourish itself and sustain its existence. He founded the field of angiogenesis research...

involved in angiogenesis. This article focuses on the important and diverse roles that these proteases play in the regulation of angiogenesis. Matrix metalloproteinases...

TNP-470 is an methionine aminopeptidase 2 inhibitor. Although it was one of the first angiogenesis inhibitor tested in clinical trials, its potential was...

antibody that functions as an angiogenesis inhibitor. It works by slowing the growth of new blood vessels by inhibiting vascular endothelial growth factor...

implicated in the initiation of angiogenesis. Dr. Judah Folkman played an important role in studying the role of angiogenesis in promoting tumor growth. He...

angiostatin and thrombospondin. Endostatin is a broad-spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors...

CW, Gupta K (December 2007). "COX-2 inhibitor celecoxib prevents chronic morphine-induced promotion of angiogenesis, tumour growth, metastasis and mortality...

series of separate therapies such as chemotherapy before surgery. Angiogenesis inhibitors are sometimes used to enhance the effects of immunotherapies. The...

in several animal species, including humans. It is an endogenous angiogenesis inhibitor (i.e., it blocks the growth of new blood vessels). Clinical trials...

class of compounds known as isoflavones. It is described as an angiogenesis inhibitor and a phytoestrogen. It was first isolated in 1899 from the dyer's...

tissue inhibitors of metalloproteinases, followed by cartilage-derived angiogenesis inhibitors. Exogenous matrix metalloproteinase inhibitors were developed...

anti-inflammatory drug use (NSAIDs), fasting, Zollinger-Ellison syndrome, angiogenesis inhibitor-treated cancer, and bariatric surgery. Peptic ulcer disease (PUD)...

molecular basis of a subtype of hereditary angioedema with normal C1-inhibitor; the mutation creates a new lysine-binding site within kringle 3 and alters...

codenamed PTK787 or PTK/ZK) is a small molecule protein kinase inhibitor that inhibits angiogenesis. It is being studied as a possible treatment for several...

This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded...

blood vessels that tumors need in order to grow (angiogenesis), hence it is an angiogenesis inhibitor. It also acts as a vasodilator and induces apoptosis...

VEGFR-2 inhibitor, also known as kinase insert domain receptor(KDR) inhibitor, are tyrosine kinase receptor inhibitors that reduce angiogenesis or lymphangiogenesis...

would cause the down-regulation of an angiogenesis inhibitor, thrombospondin-1, and the up-regulation of an angiogenesis activator which is platelet-derived...

Baas F, Unger C, et al. (January 2010). "Phase I study of the angiogenesis inhibitor BIBF 1120 in patients with advanced solid tumors". Clinical Cancer...

findings helped lead to development of the first clinically available angiogenesis inhibitor, bevacizumab (Avastin), which prevents the growth of new blood vessels...

involved in angiogenesis. Inhibition of TNF-α is not the mechanism of thalidomide's inhibition of angiogenesis since numerous other TNF-α inhibitors do not...

shown to antagonize angiogenesis (encourage termination of blood vessel formation), VASH2 has been shown to promote angiogenesis, especially in invasive...

Endothelial Growth Factor (VEGF) in the circulation and functions as an angiogenesis inhibitor. Multiple phase 3 clinical trials utilizing immunotherapy in the...