• Thumbnail for CTCF
    repressor CTCF also known as 11-zinc finger protein or CCCTC-binding factor is a transcription factor that in humans is encoded by the CTCF gene. CTCF is involved...
    26 KB (3,172 words) - 03:27, 3 December 2023
  • Thumbnail for Colorado Territorial Correctional Facility
    Correctional Facility (CTCF), colloquially known simply as "Territorial," is a medium security prison in Cañon City, Colorado. CTCF is the oldest prison...
    3 KB (293 words) - 16:44, 23 July 2024
  • many examples of insulators, including the CTCF insulator, the gypsy insulator, and the β-globin locus. The CTCF insulator is especially important in vertebrates...
    17 KB (2,065 words) - 23:02, 24 July 2024
  • Thumbnail for Cohesin
    domains (TADs) flanked by convergent CTCF binding sites form more stable chromatin loops than TADs flanked by divergent CTCF binding sites. In this model, the...
    31 KB (3,806 words) - 16:36, 7 May 2024
  • Thumbnail for Topologically associating domain
    and even across species and are highly enriched with CCCTC-binding factor (CTCF) and cohesin. In addition, some types of genes (such as transfer RNA genes...
    29 KB (3,140 words) - 02:23, 5 May 2024
  • Thumbnail for Insulin-like growth factor 2
    both IGF2 and H19 being transcribed from both parental alleles. The protein CTCF is involved in repressing expression of the gene, by binding to the H19 imprinting...
    15 KB (1,928 words) - 06:37, 31 March 2024
  • CCCTC-binding factor (CTCF) is a zinc finger protein which occurs naturally in some human cells. CTCF is localized to the nucleus of cells. CTCF has been shown...
    11 KB (1,488 words) - 20:15, 5 July 2024
  • Thumbnail for Insulated neighborhood
    In mammals, insulators are bound by CTCF, but only a minority of CTCF-bound sites function as insulators. CTCF molecules can form homodimers on DNA,...
    24 KB (2,487 words) - 06:31, 11 May 2024
  • the complex itself. CTCF, a transcription factor that limits the frontier of the DNA loop. To stop the growth of a loop, two CTCF molecules must be positioned...
    53 KB (5,924 words) - 16:38, 18 July 2024
  • Thumbnail for CTCFL
    factor (CTCF), an 11-zinc finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive...
    6 KB (741 words) - 15:08, 30 November 2023
  • Thumbnail for Nuclear organization
    active in regulating CTCF binding and therefore affect genome organization and transcription of many genes. CCCTC-binding factor (CTCF), or 11-zinc finger...
    34 KB (4,188 words) - 23:37, 16 May 2024
  • Thumbnail for Roy Best (prison warden)
    father Boon as warden of the Colorado Territorial Correctional Facility (CTCF) in Canon City. Adams later appointed Roy as warden of the same facility...
    11 KB (1,080 words) - 04:36, 24 July 2024
  • Thumbnail for Hi-C (genomic analysis technique)
    TADs, the researchers discovered increases in the number of DHS sites, CTCF binding ability, active histone modifications, and target gene expressions...
    98 KB (10,972 words) - 12:56, 11 June 2024
  • factor CTCF. She found that in the absence of CTCF, H19 becomes hypermethylated and embryos die early in development. She went on to show that CTCF was crucial...
    8 KB (820 words) - 22:00, 12 October 2023
  • Thumbnail for Granulocyte-macrophage colony-stimulating factor
    S, Baxter EW, et al. (April 2009). "A conserved insulator that recruits CTCF and cohesin exists between the closely related but divergently regulated...
    17 KB (1,672 words) - 11:59, 30 August 2023
  • Thumbnail for Progesterone receptor
    TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP...
    24 KB (2,820 words) - 05:34, 10 July 2024
  • Thumbnail for Poly (ADP-ribose) polymerase
    determining which cell death pathway has been activated. CCCTC-binding factor (CTCF) induces PAR accumulation. ADP-ribose polymers, either free or PARP1 bound...
    25 KB (3,085 words) - 18:04, 14 July 2024
  • humans it is composed of 3kb monomers containing a highly conserved CTCF binding site. CTCF is a transcription factor protein and the main insulator responsible...
    4 KB (516 words) - 01:51, 3 December 2023
  • "Ascolti tv domenica 20 febbraio 2022: L'amica geniale, Che bella giornata, CTCF" (in Italian). Retrieved February 21, 2022. Metcalf, Mitch (April 5, 2022)...
    60 KB (3,809 words) - 17:48, 25 July 2024
  • Thumbnail for TP63
    interactions, mediated by CTCF in epidermal keratinocytes. Such hubs contain multiple connecting DNA loops that require not only CTCF binding that is rather...
    21 KB (2,378 words) - 06:27, 13 July 2024
  • Thumbnail for Nucleosome
    able to "slide" along the DNA in cis. In 2008, it was further revealed that CTCF binding sites act as nucleosome positioning anchors so that, when used to...
    56 KB (6,714 words) - 23:28, 19 May 2024
  • Thumbnail for Circuit topology
    structures. Contacts in the genome are established via protein bridges including CTCF and cohesins and are measured by technologies including Hi-C. Circuit topology...
    8 KB (879 words) - 22:06, 18 June 2024
  • Thumbnail for Transcription (biology)
    The loop is stabilized by a dimer of a connector protein (e.g. dimer of CTCF or YY1), with one member of the dimer anchored to its binding motif on the...
    58 KB (6,787 words) - 11:35, 21 June 2024
  • Thumbnail for Epigenome
    are characterized by the massive presence of insulator binding proteins CTCF. Secondly, boundary regions block heterochromatin spreading, thus preventing...
    34 KB (3,802 words) - 08:24, 2 August 2024
  • Thumbnail for Epigenetics
    2014). "Nucleosome repositioning links DNA (de)methylation and differential CTCF binding during stem cell development". Genome Research. 24 (8): 1285–95....
    161 KB (18,344 words) - 08:31, 28 July 2024
  • Stong N, Plasschaert R, et al. Riethman H, and Lieberman PM. A role for CTCF and cohesion in subtelomere chromatin organization, TERRA transcription,...
    8 KB (874 words) - 09:02, 14 July 2024
  • Thumbnail for Catholic University Center of Eastern Minas Gerais
    was built and, attached to it, the Technical School of Coronel Fabriciano (CTCF) - now the Padre de Man School. Thus, the complex became the first technical...
    19 KB (1,926 words) - 23:12, 23 July 2024
  • Thumbnail for Transcription factor
    TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP...
    75 KB (8,057 words) - 04:44, 25 July 2024
  • specific TF according to literature or domain structure – No motif [127] CTCF ENSG00000102974 C2H2 ZF Known motif – High-throughput in vitro [128] CCDSBAGGKGGCGCB...
    374 KB (81 words) - 02:10, 23 September 2023
  • The loop is stabilized by a dimer of a connector protein (e.g. dimer of CTCF or YY1), with one member of the dimer anchored to its binding motif on the...
    54 KB (6,343 words) - 14:14, 17 June 2024