Cytochrome P450 4F2 is a protein that in humans is encoded by the CYP4F2 gene. This protein is an enzyme, a type of protein that catalyzes (helps speed...
79 KB (8,929 words) - 20:06, 8 August 2024
CYP4 ω-hydroxylases include CYP4A11, CYP4F2, and CYP4F3 with the predominant 20-HETE-synthesizing enzymes being CYP4F2, which is the major 20-HETE producing...
80 KB (8,949 words) - 01:48, 10 July 2024
superfamily, members of the CYP4A and CYP4F subfamilies viz., CYP4A11, CYP4F2, CYP4F3, are considered the predominant cytochrome P450 enzymes responsible...
9 KB (894 words) - 16:39, 17 August 2024
via:[citation needed] Sequencing of genes – TG1, ALOXE3, ALOX12B, NIPAL4, CYP4F2, CERS3, LIPN, etc. Measuring in situ TG1 activity in cryostat section Electron...
7 KB (585 words) - 08:01, 7 July 2024
metabolized in the liver, undergoing ω-hydroxylation by the enzymes CYP3A4 and CYP4F2, followed by β-oxidation. The final metabolites, carboxyethyl-hydroxychromanols...
20 KB (2,225 words) - 05:25, 3 June 2024
(16,17-DiETrE Cytochrome P450 microsome ω-hydroxylases: CYP4A11, CYP4A22, CYP4F2, and CYP4F3 metabolize arachidonic acid primarily to 20-hydroxyeicosatetraenoic...
84 KB (9,646 words) - 03:37, 12 August 2024
medium-chain fatty acids, i.e. fatty acids that are 10-16 carbons long; CYP4A11, CYP4F2, CYP4F3A, CYP4F3B, CYP4F11, CYP4V2, and CYP4Z1 also metabolize these fatty...
14 KB (1,685 words) - 02:13, 17 June 2024
oppose those of another product of CYP450 enzymes (e.g. CYP4A1, CYP4A11, CYP4F2, CYP4F3A, and CYP4F3B) viz., 20-Hydroxyeicosatetraenoic acid (20-HETE),...
50 KB (5,023 words) - 03:04, 8 April 2024
to 7α,25-dihydroxycholesterol, whereas 25-hydroxycholesterol can inhibit CYP4F2 mRNA expression, so that members of the cytochrome P450 family are also...
4 KB (357 words) - 10:44, 24 May 2024
Cytochrome P450 (CYP450) microsome ω-hydroxylases such as CYP4A11, CYP4A22, CYP4F2, and CYP4F3 in humans, Cyp4a10 and Cyp4a12 in mice, and Cyp4a1, Cyp4a2,...
11 KB (758 words) - 18:07, 1 May 2024
20-HETE and EETs; it also hydroxylates DHA to 22-hydroxy-DHA (i.e. 12-HDHA). CYP4F2, CYP4F3A, and CYP4F3B (see CYP4F3 for latter two CYPs) metabolize PUFAs...
42 KB (4,485 words) - 22:27, 17 July 2024
Zhang J, Chen Z, Chen C (September 2016). "Impact of CYP2C9, VKORC1 and CYP4F2 genetic polymorphisms on maintenance warfarin dosage in Han-Chinese patients:...
11 KB (1,472 words) - 14:45, 27 October 2023
CYP4F2 protein structure - Protein structure of Leukotriene-B4 omega-hydroxylase 1 enzyme. Source: Wikipedia Commons, the free media repository. Retrieved...
62 KB (6,668 words) - 14:56, 30 June 2024
Q02928 3897 CYP4A22 HGNC:20575 Q5TCH4 3898 CYP4B1 HGNC:2644 P13584 3899 CYP4F2 HGNC:2645 P78329 3900 CYP4F3 HGNC:2646 Q08477 3901 CYP4F8 HGNC:2648 P98187...
277 KB (17 words) - 23:17, 27 April 2024
acid (20-HETE). In humans, the major CYPs making 20-HETE are CYP4A11, CYP4F2, and CYP4F3. In animal models, 20-HETE raises blood pressure by contracting...
48 KB (5,934 words) - 14:58, 24 January 2024
is highly expressed in the liver and kidney. CYP4A11 along with CYP4A22, CYP4F2, and CYP4F3 metabolize arachidonic acid to 20-Hydroxyeicosatetraenoic acid...
21 KB (2,570 words) - 14:22, 24 January 2024
genes on chromosome 1p33. CYP4A22 was once considered, along with CYP4A11, CYP4F2, and CYP4F3, as active in metabolizing arachidonic acid to 20-hydroxyeicosatetraenoic...
5 KB (615 words) - 17:50, 11 January 2024
cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants...
9 KB (1,186 words) - 06:05, 12 January 2024
and N-myristoylation. Predicted interaction partners include APOA2 and CYP4F2. TMEM82 has been found to coexpress with proteins involved in lipids, hormones...
14 KB (1,200 words) - 14:17, 21 July 2024
dampening inflammatory responses and the reported associations of certain CYP4F2 and CYP4F3 single nucleotide variants with human Krohn's disease and Coeliac...
9 KB (1,124 words) - 04:53, 15 December 2023
CYP1A2, CYP2C8, CYP2C9, CYP2C18, CYP2C19, CYP2E1, CYP2J2, CYP2S1, CYP3A4, CYP4F2, CYP4F3A, CYP4F3B, CYP4A11, CYP4F8, and CYP4F12. CYP2C8 and CYP2C9 form...
41 KB (4,771 words) - 12:28, 14 June 2024