In pharmacology, clearance ( C l t o t {\displaystyle Cl_{tot}} ) is a pharmacokinetic parameter representing the efficiency of drug elimination. This...
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control clearance in aviation Security clearance, a status granted to individuals allowing them access to classified information Clearance (pharmacology), the...
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produced by the body, whereas inulin has to be intravenously infused. Clearance (pharmacology) Kt/V Rudolfs K. Zalups; Lawrence H. Lash (1996). Methods in Renal...
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points in time and the trapezoidal rule is used to estimate AUC. In pharmacology, the area under the plot of plasma concentration of a drug versus time...
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In pharmacology, augmented renal clearance (ARC) is a phenomenon where certain critically ill patients may display increased clearance of a medication...
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In pharmacology, the elimination or excretion of a drug is understood to be any one of a number of processes by which a drug is eliminated (that is, cleared...
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Bioavailability (redirect from Active (pharmacology))
In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation....
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discussion 1193–7. PMID 17716385. Rubin, Bruce K. (2006). "The pharmacologic approach to airway clearance: Mucoactive agents". Paediatric Respiratory Reviews. 7...
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fast enough to sample dynamics of neurotransmitter release and clearance. Pharmacological action of dopaminergic drugs such as D1 and D2 receptors agonists...
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or central vein. In pharmacology, the route of drug administration is important because it affects drug metabolism, drug clearance, and thus dosage. The...
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In the field of drug discovery, reverse pharmacology also known as target-based drug discovery (TDD), a hypothesis is first made that modulation of the...
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In the field of drug discovery, classical pharmacology, also known as forward pharmacology, or phenotypic drug discovery (PDD), relies on phenotypic screening...
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IC50 is commonly used as a measure of antagonist drug potency in pharmacological research. IC50 is comparable to other measures of potency, such as...
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Bisoprolol (section Pharmacology)
approximately 35%, the volume of distribution is 3.5 L/kg and the total clearance is approximately 15 L/h. Bisoprolol is eliminated from the body in two...
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The pharmacology of ethanol involves both pharmacodynamics (how it affects the body) and pharmacokinetics (how the body processes it). In the body, ethanol...
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mainly excreted by tubular secretion in the kidney. In kidney impairment, clearance is reduced, increasing the risk of adverse effects. Lower initial doses...
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Cyclobenzaprine (section Pharmacology)
in plasma. The half-life of the drug is 18 hours and it has a plasma clearance of 0.7 litres per minute. Cyclobenzaprine has been found to be not inferior...
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Olanzapine (section Pharmacology)
hepatic first-pass effect. Clearance of olanzapine appears to vary by sex; women have roughly 25% lower clearance than men. Clearance of olanzapine also varies...
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Amitriptyline (section Pharmacology)
contribution of CYP3A to amitriptyline clearance in humans: in vitro and in vivo studies". Journal of Clinical Pharmacology. 41 (10): 1043–1054. doi:10.1177/00912700122012634...
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Maropitant (section Pharmacology)
information) Riviere JE, Papich MG (2017). "Maropitant". Veterinary Pharmacology and Therapeutics. John Wiley & Sons. p. 2828. ISBN 978-1-118-85588-1...
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Phencyclidine (section Pharmacology)
Chemically, PCP is a member of the arylcyclohexylamine class, and pharmacologically, it is a dissociative anesthetic. PCP works primarily as an NMDA receptor...
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Chlorpromazine (section Pharmacology)
can increase chlorpromazine clearance significantly. Tricyclic antidepressants (TCAs) can decrease chlorpromazine clearance and hence increase chlorpromazine...
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In pharmacology, the volume of distribution (VD, also known as apparent volume of distribution, literally, volume of dilution) is the theoretical volume...
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Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication)...
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Lithium (medication) (redirect from Lithum pharmacology)
(October 2014). "Lithium: a review of pharmacology, clinical uses, and toxicity". European Journal of Pharmacology. 740 (740): 464–473. doi:10.1016/j.ejphar...
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Dobutamine (section Pharmacology)
ISBN 978-0-85711-338-2. Rang HP, Dale MM, Ritter JM, Flower RJ. Rang and Dale's Pharmacology. Tariq S, Aronow WS (December 2015). "Use of Inotropic Agents in Treatment...
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Theophylline (section Pharmacology)
to treat chronic obstructive pulmonary disease (COPD) and asthma. Its pharmacology is similar to other methylxanthine drugs (e.g., theobromine and caffeine)...
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Route of administration (redirect from Local administration (pharmacology))
In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. Routes...
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Hypersalivation (section Decreased clearance)
amount of saliva in the mouth, which may also be caused by decreased clearance of saliva. Hypersalivation can contribute to drooling if there is an inability...
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Clonidine (section Pharmacology)
(November 2011). "Clonidine: clinical pharmacology and therapeutic use in pain management". Current Clinical Pharmacology. 6 (4): 280–287. doi:10.2174/157488411798375886...
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