• In pharmacology, clearance ( C l t o t {\displaystyle Cl_{tot}} ) is a pharmacokinetic parameter representing the efficiency of drug elimination. This...
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  • control clearance in aviation Security clearance, a status granted to individuals allowing them access to classified information Clearance (pharmacology), the...
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  • Thumbnail for Renal clearance ratio
    produced by the body, whereas inulin has to be intravenously infused. Clearance (pharmacology) Kt/V Rudolfs K. Zalups; Lawrence H. Lash (1996). Methods in Renal...
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  • points in time and the trapezoidal rule is used to estimate AUC. In pharmacology, the area under the plot of plasma concentration of a drug versus time...
    11 KB (1,271 words) - 08:43, 18 August 2023
  • In pharmacology, augmented renal clearance (ARC) is a phenomenon where certain critically ill patients may display increased clearance of a medication...
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  • Thumbnail for Elimination (pharmacology)
    In pharmacology, the elimination or excretion of a drug is understood to be any one of a number of processes by which a drug is eliminated (that is, cleared...
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  • In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation....
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  • discussion 1193–7. PMID 17716385. Rubin, Bruce K. (2006). "The pharmacologic approach to airway clearance: Mucoactive agents". Paediatric Respiratory Reviews. 7...
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  • Thumbnail for Fast-scan cyclic voltammetry
    fast enough to sample dynamics of neurotransmitter release and clearance. Pharmacological action of dopaminergic drugs such as D1 and D2 receptors agonists...
    11 KB (1,268 words) - 09:01, 12 October 2023
  • Thumbnail for Enteral administration
    or central vein. In pharmacology, the route of drug administration is important because it affects drug metabolism, drug clearance, and thus dosage. The...
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  • Thumbnail for Reverse pharmacology
    In the field of drug discovery, reverse pharmacology also known as target-based drug discovery (TDD), a hypothesis is first made that modulation of the...
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  • Thumbnail for Classical pharmacology
    In the field of drug discovery, classical pharmacology, also known as forward pharmacology, or phenotypic drug discovery (PDD), relies on phenotypic screening...
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  • Thumbnail for IC50
    IC50 is commonly used as a measure of antagonist drug potency in pharmacological research. IC50 is comparable to other measures of potency, such as...
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  • Thumbnail for Bisoprolol
    approximately 35%, the volume of distribution is 3.5 L/kg and the total clearance is approximately 15 L/h. Bisoprolol is eliminated from the body in two...
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  • Thumbnail for Pharmacology of ethanol
    The pharmacology of ethanol involves both pharmacodynamics (how it affects the body) and pharmacokinetics (how the body processes it). In the body, ethanol...
    96 KB (10,550 words) - 10:57, 20 July 2024
  • Thumbnail for Furosemide
    mainly excreted by tubular secretion in the kidney. In kidney impairment, clearance is reduced, increasing the risk of adverse effects. Lower initial doses...
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  • Thumbnail for Cyclobenzaprine
    in plasma. The half-life of the drug is 18 hours and it has a plasma clearance of 0.7 litres per minute. Cyclobenzaprine has been found to be not inferior...
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  • Thumbnail for Olanzapine
    hepatic first-pass effect. Clearance of olanzapine appears to vary by sex; women have roughly 25% lower clearance than men. Clearance of olanzapine also varies...
    92 KB (8,663 words) - 12:39, 5 August 2024
  • Thumbnail for Amitriptyline
    contribution of CYP3A to amitriptyline clearance in humans: in vitro and in vivo studies". Journal of Clinical Pharmacology. 41 (10): 1043–1054. doi:10.1177/00912700122012634...
    92 KB (8,671 words) - 18:15, 17 August 2024
  • Thumbnail for Maropitant
    information) Riviere JE, Papich MG (2017). "Maropitant". Veterinary Pharmacology and Therapeutics. John Wiley & Sons. p. 2828. ISBN 978-1-118-85588-1...
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  • Thumbnail for Phencyclidine
    Chemically, PCP is a member of the arylcyclohexylamine class, and pharmacologically, it is a dissociative anesthetic. PCP works primarily as an NMDA receptor...
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  • Thumbnail for Chlorpromazine
    can increase chlorpromazine clearance significantly. Tricyclic antidepressants (TCAs) can decrease chlorpromazine clearance and hence increase chlorpromazine...
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  • In pharmacology, the volume of distribution (VD, also known as apparent volume of distribution, literally, volume of dilution) is the theoretical volume...
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  • Thumbnail for Biological half-life
    Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication)...
    23 KB (2,510 words) - 05:34, 5 August 2024
  • Thumbnail for Lithium (medication)
    (October 2014). "Lithium: a review of pharmacology, clinical uses, and toxicity". European Journal of Pharmacology. 740 (740): 464–473. doi:10.1016/j.ejphar...
    92 KB (9,852 words) - 18:28, 14 August 2024
  • Thumbnail for Dobutamine
    ISBN 978-0-85711-338-2. Rang HP, Dale MM, Ritter JM, Flower RJ. Rang and Dale's Pharmacology. Tariq S, Aronow WS (December 2015). "Use of Inotropic Agents in Treatment...
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  • Thumbnail for Theophylline
    to treat chronic obstructive pulmonary disease (COPD) and asthma. Its pharmacology is similar to other methylxanthine drugs (e.g., theobromine and caffeine)...
    24 KB (2,233 words) - 13:40, 28 May 2024
  • Thumbnail for Route of administration
    In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. Routes...
    43 KB (4,411 words) - 22:36, 14 August 2024
  • amount of saliva in the mouth, which may also be caused by decreased clearance of saliva. Hypersalivation can contribute to drooling if there is an inability...
    6 KB (493 words) - 20:30, 16 August 2024
  • Thumbnail for Clonidine
    (November 2011). "Clonidine: clinical pharmacology and therapeutic use in pain management". Current Clinical Pharmacology. 6 (4): 280–287. doi:10.2174/157488411798375886...
    60 KB (5,506 words) - 21:49, 10 July 2024