• immunology, clonal deletion is the process of removing T and B lymphocytes from the immune system repertoire. The process of clonal deletion helps prevent...
    13 KB (1,640 words) - 04:12, 7 May 2024
  • pre-existing clones of lymphocytes, which expand in response to specific antigen (process called "clonal selection"). This specific clonal army then combats...
    16 KB (1,939 words) - 20:19, 27 June 2024
  • anemone, also called clonal anemone Vegetative cloning, a form of asexual reproduction in plants Clonal reproduction Clonal deletion, a process by which...
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  • food antigens and allergens. Self reactive cells are subject to clonal deletion or clonal diversion. Both processes of peripheral tolerance control the...
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  • Thumbnail for Medullary thymic epithelial cells
    ability to deal with these autoreactive clones via mediation of the processes of central tolerance, namely clonal deletion or T regulatory cells selection, respectively...
    29 KB (3,544 words) - 07:37, 20 April 2024
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    strongly to self-antigen, then the B cell undergoes one of four fates: clonal deletion, receptor editing, anergy, or ignorance (B cell ignores signal and...
    32 KB (3,752 words) - 12:16, 26 April 2024
  • bind a self peptide, then they are signaled to apoptose (process of clonal deletion). The thymic epithelial cells display self antigen to the T cells to...
    32 KB (4,109 words) - 02:39, 24 June 2024
  • Thumbnail for Deletion (genetics)
    In genetics, a deletion (also called gene deletion, deficiency, or deletion mutation) (sign: Δ) is a mutation (a genetic aberration) in which a part of...
    14 KB (1,537 words) - 02:33, 14 May 2024
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    receptor. Both activated T cells and B cells express Fas and undergo clonal deletion by the AICD mechanism. Activated T cells that express both Fas and...
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  • tolerance. Just as in T cells, clonal deletion and clonal anergy can physically eliminate autoreactive B cell clones. Receptor editing is another mechanism...
    28 KB (4,099 words) - 05:30, 10 June 2024
  • Sprent, Jonathan, and Susan R. Webb. "Intrathymic and extrathymic clonal deletion of T cells." Current opinion in immunology 7.2 (1995): 196-205. Crotty...
    20 KB (2,449 words) - 18:34, 29 June 2024
  • is allowed to proliferate or is killed off through a process called clonal deletion. Normally, the immune system is able to recognize and ignore the body's...
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  • Thumbnail for Autoimmunity
    Three hypotheses have gained widespread attention among immunologists: Clonal deletion theory, proposed by Burnet, according to which self-reactive lymphoid...
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  • dendritic cell with T cell receptors on the T cell. This can induce T cell clonal deletion, T cell anergy or the proliferation of regulatory T cells (Tregs)....
    10 KB (1,181 words) - 11:38, 21 July 2021
  • processes of central tolerance take place in thymic medulla, namely clonal deletion (recessive tolerance) and T Regulatory cells selection (dominant tolerance)...
    16 KB (1,927 words) - 20:14, 1 June 2022
  • abrogated by thymus-dependent dextran conjugates: evidence against clonal deletion as the mechanism of tolerance induction". Scandinavian Journal of Immunology...
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  • Thumbnail for Microchimerism
    In mice models, most mother's fetal-specific CD8+ T cells undergo clonal deletion and express low levels of chemokine receptors and ligands – this prevents...
    43 KB (5,130 words) - 09:24, 19 February 2024
  • were the first to propose the deletion of self-reactive lymphocytes to establish tolerance, now termed clonal deletion. Burnet and Medawar were ultimately...
    50 KB (6,028 words) - 07:46, 12 July 2024
  • activity is selective but is not T-cell receptor mediated. Both clonal anergy and clonal deletion have been shown to operate in vetoed T cells. The veto cell...
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    Whitacre CC, Liu Y, Bai XF (July 2008). "Autoreactive T cells escape clonal deletion in the thymus by a CD24-dependent pathway". Journal of Immunology....
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  • maintenance of central and peripheral tolerance through induction of T cell clonal deletion, T cell anergy and generation and activation of regulatory T (Treg)...
    23 KB (2,765 words) - 17:17, 20 November 2023
  • anti-CD4 monoclonal antibodies, demonstrating that neither thymus nor clonal deletion is necessary to induce tolerance. In 1989 was successfully induced...
    11 KB (1,224 words) - 22:58, 28 May 2024
  • yeast deletion project, formally the Saccharomyces Genome Deletion Project, is a project to create data for a near-complete collection of gene-deletion mutants...
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  • 16p11.2 deletion syndrome is a rare genetic condition caused by microdeletion on the short arm of chromosome 16. Most affected individuals experience global...
    14 KB (1,064 words) - 23:48, 7 July 2024
  • Most T cells are, in time, eliminated in the thymus by a process of clonal deletion. However, some of them escape this process and are then "mopped up"...
    16 KB (1,792 words) - 09:42, 17 March 2023
  • Retrieved December 11, 2020. Dumarog, Ana (April 29, 2021). "Loki Faces Deletion From Reality According To New TV Show Synopsis". Screen Rant. Archived...
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  • Thumbnail for Multiple myeloma
    t(14;20).. Other genetic alterations are 1q amplification, deletion 1p, deletion 17, deletion 13, MYC overexpression, and point mutations in key pathways...
    132 KB (13,496 words) - 21:17, 11 July 2024
  • Cross-reactivity Tolerance Central tolerance Peripheral tolerance Clonal anergy Clonal deletion Tolerance in pregnancy Immunodeficiency Antigen Antigenicity...
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  • Cholinergic anti-inflammatory pathway CLIP (protein) Clonal anergy Clonal deletion Clonal selection Clone (cell biology) CMKLR1 Colony stimulating factor 1...
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  • been removed from the original 2,315 Wordle answers. Because of these deletions, the Times version of Wordle is now out of synchronization with cached...
    56 KB (5,360 words) - 22:44, 26 June 2024