Dasatinib, sold under the brand name Sprycel among others, is a targeted therapy medication used to treat certain cases of chronic myelogenous leukemia...
22 KB (1,994 words) - 08:45, 4 November 2024
to TK inhibitors, four novel agents were later developed. The first, dasatinib, blocks several further oncogenic proteins, in addition to more potent...
34 KB (3,877 words) - 13:44, 25 October 2024
except for T315I. Dasatinib is also not a substrate of multidrug P-glycoprotein efflux pumps like imatinib. Because of this dasatinib may be active in...
56 KB (6,470 words) - 20:27, 19 November 2024
are repurposed anti-cancer molecules, such as the chemotherapeutic drug dasatinib and the experimental small molecule navitoclax. Soluble urokinase plasminogen...
26 KB (2,028 words) - 14:35, 22 November 2024
sofosbuvir, afatinib, axitinib, brigatinib, baricitinib, cabozantinib, dasatinib, neratinib, eltrombopag, ibrutinib, lenvatinib, palbociclib, regorafenib...
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kinases) have been developed for therapeutic use. One notable example is dasatinib which has been approved for the treatment of chronic myeloid leukemia...
21 KB (2,648 words) - 12:12, 26 July 2024
alefacept, and the tyrosine kinase inhibitors, imatinib, nilotinib, and dasatinib. Experimental therapies under investigation include endothelin receptor...
38 KB (3,293 words) - 18:29, 29 August 2024
symptoms. Among currently available inhibitors to treat CML are imatinib, dasatinib, nilotinib, bosutinib and ponatinib. Gastrointestinal stromal tumors (GIST)...
43 KB (5,251 words) - 10:44, 24 June 2024
are point-mutations in the kinase of BCR-abl. New inhibitors include dasatinib and nilotinib, which are significantly more potent than imatinib and may...
29 KB (3,538 words) - 15:01, 5 December 2023
Agonists: Ancestim Stem cell factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib...
121 KB (13,799 words) - 10:33, 13 November 2024
D+Q may refer to: Dasatinib#Dasatinib+Quercetin Drawn & Quarterly This disambiguation page lists articles associated with the title D+Q. If an internal...
231 bytes (42 words) - 03:27, 19 December 2023
lung-related adverse effects are rare when compared with imatinib and dasatinib, there is a case report of acute respiratory failure from diffuse alveolar...
23 KB (1,865 words) - 06:18, 13 November 2024
leukemia (CML) and later gefitinib and erlotinib aiming at the EGF receptor. Dasatinib is a Src tyrosine kinase inhibitor that is effective both as a senolytic...
10 KB (1,179 words) - 18:31, 8 August 2024
T315I) and some dasatinib resistant mutations. Bafetinib also has more affinity for Bcr-Abl than nilotinib (but less than dasatinib) but only targets...
8 KB (733 words) - 11:36, 12 August 2023
2006: FDA Approval of Dasatinib and Nilotinib for Resistant Leukemia MD Anderson researchers demonstrate the efficacy of dasatinib and nilotinib, leading...
54 KB (5,298 words) - 18:20, 16 October 2024
Meclozine MT-45 Oxatomide SNC-80 Vanoxerine Pyrimidinylpiperazines Buspirone Dasatinib Eptapirone Gepirone Ipsapirone Piribedil Pyrimidinylpiperazine Revospirone...
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(Eli Lilly and Company) darifenacin hydrochloride (USAN) Darzalex Faspro dasatinib (USAN, INN) datelliptium chloride (INN) DaTSCAN (GE Healthcare) Daunorubicin...
6 KB (331 words) - 04:31, 10 November 2024
Agonists: Ancestim Stem cell factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib...
93 KB (8,729 words) - 06:34, 10 November 2024
Meclozine MT-45 Oxatomide SNC-80 Vanoxerine Pyrimidinylpiperazines Buspirone Dasatinib Eptapirone Gepirone Ipsapirone Piribedil Pyrimidinylpiperazine Revospirone...
22 KB (1,723 words) - 20:48, 13 November 2024
agents. PP1, PP2 (kinase inhibitor) are both inhibitors of Lck and FynT. Dasatinib Rivera-Torres J, José ES (2019). "Src Tyrosine Kinase Inhibitors: New...
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due to drug or toxin exposures. Methamphetamines, the chemotherapeutic dasatinib and the appetite suppressant and diet drug fenfluramine are associated...
23 KB (2,753 words) - 03:42, 16 September 2024
Meclozine MT-45 Oxatomide SNC-80 Vanoxerine Pyrimidinylpiperazines Buspirone Dasatinib Eptapirone Gepirone Ipsapirone Piribedil Pyrimidinylpiperazine Revospirone...
83 KB (7,400 words) - 11:11, 2 November 2024
Agonists: Ancestim Stem cell factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib...
72 KB (6,433 words) - 04:45, 17 November 2024
Agonists: Ancestim Stem cell factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib...
149 KB (15,703 words) - 16:01, 5 November 2024
Agonists: Ancestim Stem cell factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib...
13 KB (1,177 words) - 01:44, 4 November 2024
Asparaginase Cladribine Clofarabine Cyclophosphamide Cytosine arabinoside Dasatinib Daunorubicin Decitabine Etoposide Fludarabine Gemtuzumab ozogamicin Idarubicin...
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Agonists: Ancestim Stem cell factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib...
42 KB (3,937 words) - 11:44, 15 November 2024
replaced gefitinib in this setting. Sorafenib (Nexavar) Sunitinib (Sutent) Dasatinib (Sprycel) Lapatinib (Tykerb) Nilotinib (Tasigna) Bosutinib (Bosulif) Ponatinib...
20 KB (2,234 words) - 01:21, 22 July 2024
functions to overcome other disease drivers. Kinase inhibitors such as dasatinib are often used in the treatment of cancer and inflammation. Some of the...
23 KB (750 words) - 23:26, 13 August 2024
Meclozine MT-45 Oxatomide SNC-80 Vanoxerine Pyrimidinylpiperazines Buspirone Dasatinib Eptapirone Gepirone Ipsapirone Piribedil Pyrimidinylpiperazine Revospirone...
10 KB (814 words) - 04:38, 1 August 2024