Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. Desmoglein-2 is highly expressed in epithelial cells and cardiomyocytes. Desmoglein-2...
20 KB (2,276 words) - 16:13, 15 August 2023
Desmoglein-3 is a protein that in humans is encoded by the DSG3 gene. In the skin epidermis Desmoglein-3 is expressed in the basal lower layers of the...
11 KB (1,387 words) - 23:18, 26 January 2024
The desmogleins are a family of desmosomal cadherins consisting of proteins DSG1, DSG2, DSG3, and DSG4. They play a role in the formation of desmosomes...
3 KB (326 words) - 20:06, 28 January 2024
Desmoglein-1 is a protein that in humans is encoded by the DSG1 gene. Desmoglein-1 is expressed everywhere in the skin epidermis, but mainly it is expressed...
13 KB (1,598 words) - 16:13, 15 August 2023
The extracellular core region, approximately 34 nm in length, contains desmoglein and desmocollin, which are in the cadherin family of cell adhesion proteins...
10 KB (1,219 words) - 11:10, 14 July 2024
Towbin J, Thiene G, Danieli GA, Rampazzo A (March 2006). "Mutations in desmoglein-2 gene are associated with arrhythmogenic right ventricular cardiomyopathy"...
49 KB (5,642 words) - 07:53, 3 July 2024
Desmoglein-4 is a protein that in humans is encoded by the DSG4 gene. List of conditions caused by problems with junctional proteins GRCh38: Ensembl release...
5 KB (455 words) - 16:14, 15 August 2023
desmogleins to link adjacent cells by extracellular adhesion. There are seven desmosomal cadherins in humans, three desmocollins and four desmogleins...
7 KB (732 words) - 16:38, 15 August 2023
desmoglein 1. The effect of the antibodies and the immunological pathway is most likely one of three mechanisms: Steric hindrance of the desmoglein 1:...
8 KB (889 words) - 15:18, 29 May 2024
autoimmune disease caused by antibodies directed against both desmoglein 1 and desmoglein 3 present in desmosomes. Loss of desmosomes results in loss of...
17 KB (1,941 words) - 14:31, 22 March 2024
Saftig P., Baselga J., Arribas J., Canals F. Proteomic identification of desmoglein 2 and activated leukocyte cell adhesion molecule as substrates of ADAM17...
36 KB (5,012 words) - 20:38, 12 July 2024
pemphix, meaning "blister". In pemphigus, autoantibodies form against desmoglein, which forms the "glue" that attaches adjacent epidermal cells via attachment...
19 KB (1,951 words) - 13:36, 28 May 2024
Exfoliating toxins are serine proteases that specifically bind to and cleave desmoglein 1 (Dsg1). Previous studies suggested that exfoliating toxins bind to gangliosides...
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catenin, desmocollin 1, desmocollin 2, desmoglein 1, desmoglein 2, desmoplakin, connexin 43, plakoglobin, Kir6.2, and SCN5A. Skin fragility syndrome GRCh38:...
34 KB (4,002 words) - 22:48, 25 April 2024
200.500.500 – desmogleins MeSH D12.776.543.550.200.200.500.500.500 – desmoglein 1 MeSH D12.776.543.550.200.200.500.500.625 – desmoglein 2 MeSH D12.776...
121 KB (11,308 words) - 16:43, 9 February 2024
dermatosis type of IgA pemphigus Desmocollin 2 Arrhythmogenic right ventricular dysplasia (ARVD) Desmoglein 1 Striate palmoplantar keratoderma Pemphigus...
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other is encoded on a plasmid. These exotoxins are proteases that cleave desmoglein-1, which normally holds the granulosum and spinosum layers together, similar...
8 KB (825 words) - 17:00, 1 March 2023
component of desmosomes, where it can bind to the cadherin family member desmoglein I. Plakoglobin also associates with classical cadherins such as E-cadherin;...
40 KB (4,695 words) - 21:17, 8 April 2024
cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive...
7 KB (910 words) - 10:51, 24 December 2023
350.200.500.500 – desmogleins MeSH D23.050.301.350.200.500.500.500 – desmoglein 1 MeSH D23.050.301.350.200.500.500.625 – desmoglein 2 MeSH D23.050.301...
86 KB (8,039 words) - 16:46, 9 February 2024
DSC2 (redirect from Desmocollin 2)
transmembrane-spanning domain, and a C-terminal cytoplasmic tail. Desmocollin-2 binds to desmoglein family members through a calcium-dependent interaction with its extracellular...
24 KB (2,557 words) - 22:18, 2 December 2023
200.500.500 – desmogleins MeSH D12.776.395.550.200.200.500.500.500 – desmoglein 1 MeSH D12.776.395.550.200.200.500.500.625 – desmoglein 2 MeSH D12.776...
13 KB (778 words) - 16:46, 9 February 2024
"Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity". Nat Genet. 37 (1): 56–65. doi:10...
10 KB (1,119 words) - 17:24, 4 July 2024
IgG autoantibodies that are characteristically raised against desmoglein 1 and desmoglein 3 (which are cell-cell adhesion molecules found in desmosomes)...
28 KB (2,358 words) - 16:27, 5 March 2024
muscle/anti-actin autoantibodies in celiac disease". Acta Gastroenterol. Latinoam. 35 (2): 83–93. PMID 16127984. Carroccio A, Brusca I, Iacono G, et al. (2007). "IgA...
18 KB (1,555 words) - 19:01, 1 March 2024
"Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity". Nat Genet. 37 (1): 56–65. doi:10...
9 KB (959 words) - 00:35, 15 August 2023
complexes. The cadherin superfamily includes cadherins, protocadherins, desmogleins, desmocollins, and more. In structure, they share cadherin repeats, which...
32 KB (3,594 words) - 14:17, 13 May 2024
Rochelle R. (2014). "Lifetime Incidence Risk of Alopecia Areata Estimated at 2.1% by Rochester Epidemiology Project, 1990–2009". Journal of Investigative...
94 KB (6,052 words) - 07:45, 11 June 2024
antigens have been found to include desmoglein-3, desmoglein-1, envoplakin, periplakin, desmoplakin 1, desmoplakin 2, and bullous pemphigoid antigen I.[citation...
21 KB (2,526 words) - 21:24, 12 August 2023
N-terminal region of plakophilin 1 and plakoglobin as well as desmocollin and desmoglein. This is further sub divided into a region called the "Plakin domain"...
28 KB (3,242 words) - 15:17, 21 December 2023