Elexacaftor/tezacaftor/ivacaftor, sold under the brand names Trikafta and Kaftrio, is a fixed-dose combination medication used to treat cystic fibrosis...

lumacaftor/ivacaftor, tezacaftor/ivacaftor, and elexacaftor/tezacaftor/ivacaftor which are used to treat people with cystic fibrosis. Ivacaftor was developed...

the FDA approved Vertex's Triple-combo therapy Trikafta (elexacaftor/tezacaftor/ivacaftor) for patients 12 and older with at least one F508del mutation...

with ivacaftor under the brand name Symdeko. It was approved by the U.S. FDA in 2018. The combination of elexacaftor, tezacaftor, and ivacaftor is being...

available in a single pill with ivacaftor and tezacaftor; the fixed-dose combination, elexacaftor/tezacaftor/ivacaftor (brand name Trikafta), is used to...

people with the F508del mutation. In 2019, the combination drug elexacaftor/ivacaftor/tezacaftor, marketed as Trikafta,was approved for CF patients over the...

endometrial carcinoma Lenvatinib Eisai endometrial carcinoma Elexacaftor/tezacaftor/ivacaftor Vertex Pharmaceuticals cystic fibrosis Zanubrutinib BeiGene...

together with ivacaftor. The FDA approved this drug combination in 2015. Further research led to the discovery of tezacaftor and elexacaftor, 2 other correctors...

approved CFTR modulators for specific mutations. One such drug is elexacaftor/tezacaftor/ivacaftor. However, the cost of CFTR modulators is high. In addition...

oxide R07AX02 Ivacaftor R07AX30 Ivacaftor and lumacaftor R07AX31 Ivacaftor and tezacaftor R07AX32 Ivacaftor, tezacaftor and elexacaftor "ATC (Anatomical...

recently, Grootenhuis's team discovered Tezacaftor (VX-661) and Elexacaftor (VX-445), which in combination with Ivacaftor are the components of Trikafta, a...