• Thumbnail for Enzyme inhibitor
    An enzyme inhibitor is a molecule that binds to an enzyme and blocks its activity. Enzymes are proteins that speed up chemical reactions necessary for...
    104 KB (11,579 words) - 19:29, 18 September 2024
  • Thumbnail for ACE inhibitor
    lowering blood pressure. As a result of inhibiting the ACE enzyme in the bradykinin system, the ACE inhibitor drugs allow for increased levels of bradykinin...
    64 KB (7,025 words) - 15:10, 24 September 2024
  • Thumbnail for Enzyme
    and the inhibitor affect each other. The enzyme's function is reduced but not eliminated when bound to the inhibitor. This type of inhibitor does not...
    96 KB (9,821 words) - 16:54, 27 October 2024
  • affinity for the substrate in the enzyme is decreased in the presence of an inhibitor. The inhibitor may bind to the enzyme whether or not the substrate has...
    14 KB (1,809 words) - 08:49, 29 June 2024
  • Thumbnail for Active site
    active site and an enzyme inhibitor. If the enzyme found in bacteria is significantly different from the human enzyme then an inhibitor can be designed against...
    41 KB (4,859 words) - 19:37, 18 September 2024
  • inhibition or inhibitor in Wiktionary, the free dictionary. Inhibitor or inhibition may refer to: Enzyme inhibitor, a substance that binds to an enzyme and decreases...
    2 KB (271 words) - 19:42, 25 May 2023
  • Thumbnail for Monoamine oxidase inhibitor
    Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A)...
    37 KB (4,010 words) - 17:19, 13 October 2024
  • Thumbnail for Enzyme kinetics
    activity is controlled, and how a drug or a modifier (inhibitor or activator) might affect the rate. An enzyme (E) is a protein molecule that serves as a biological...
    71 KB (9,341 words) - 03:06, 26 August 2024
  • Thumbnail for Angioedema
    inherited problem known as C1 esterase inhibitor deficiency, medications known as angiotensin-converting enzyme inhibitors, or a lymphoproliferative disorder...
    26 KB (2,990 words) - 03:30, 17 November 2024
  • of COX-2 inhibitors. The inhibition of COX-2 is paramount for the anti-inflammatory and analgesic function of the selective COX-2 inhibitor celecoxib...
    42 KB (4,944 words) - 11:56, 4 April 2024
  • Thumbnail for Suicide inhibition
    inhibitor binds to the active site where it is modified by the enzyme to produce a reactive group that reacts irreversibly to form a stable inhibitor-enzyme...
    5 KB (590 words) - 14:06, 30 October 2024
  • Thumbnail for Competitive inhibition
    competitive inhibition of enzyme catalysis, binding of an inhibitor prevents binding of the target molecule of the enzyme, also known as the substrate...
    22 KB (2,864 words) - 06:23, 6 August 2024
  • Thumbnail for Angiotensin-converting enzyme
    ISBN 978-3-319-09787-9. Dicpinigaitis PV (January 2006). "Angiotensin-converting enzyme inhibitor-induced cough: ACCP evidence-based clinical practice guidelines". Chest...
    24 KB (2,558 words) - 14:40, 15 October 2024
  • Thumbnail for Aromatic L-amino acid decarboxylase inhibitor
    decarboxylase inhibitor (synonyms: DOPA decarboxylase inhibitor, extracerebral decarboxylase inhibitor, DDCI and AAADI) is a medication of type enzyme inhibitor which...
    4 KB (392 words) - 15:59, 16 October 2024
  • Thumbnail for Alpha-1 antitrypsin
    gene. A protease inhibitor, it is also known as alpha1–proteinase inhibitor (A1PI) or alpha1-antiproteinase (A1AP) because it inhibits various proteases...
    33 KB (3,383 words) - 08:00, 21 August 2024
  • most common classes prescribed are diuretics, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin II receptor blockers (ARBs), calcium channel...
    46 KB (5,036 words) - 18:54, 5 November 2024
  • Thumbnail for Proton-pump inhibitor
    target for inhibiting acid secretion.[citation needed] Because the H,K-ATPase is the final step of acid secretion, an inhibitor of this enzyme is more effective...
    58 KB (6,306 words) - 03:11, 9 November 2024
  • Thumbnail for Β-Lactamase inhibitor
    β-lactamase inhibitor. β-lactamase inhibitors expand the useful spectrum of these β-lactam antibiotics by inhibiting the β-lactamase enzymes produced by...
    16 KB (1,696 words) - 06:05, 21 November 2024
  • Thumbnail for Protease
    Protease (redirect from Proteolytic enzyme)
    Protease inhibitor (pharmacology) Protease inhibitor (biology) TopFIND - database of protease specificity, substrates, products and inhibitors MEROPS -...
    26 KB (2,798 words) - 18:05, 19 November 2024
  • Thumbnail for Ramipril
    Ramipril (category ACE inhibitors)
    is located at the active site of the ACE enzyme. Ramipril is similar in structure to another ACE Inhibitor, trandolapril, but it has a second cyclopentane...
    19 KB (1,876 words) - 05:43, 28 October 2024
  • Thumbnail for Cholesterol side-chain cleavage enzyme
    cleavage enzyme is commonly referred to as P450scc, where "scc" is an abbreviation for side-chain cleavage. P450scc is a mitochondrial enzyme that catalyzes...
    24 KB (2,657 words) - 16:15, 30 August 2024
  • Thumbnail for Nonsteroidal anti-inflammatory drug
    1948. NSAIDs work by inhibiting the activity of cyclooxygenase enzymes (the COX-1 and COX-2 isoenzymes). In cells, these enzymes are involved in the synthesis...
    111 KB (11,577 words) - 07:56, 16 November 2024
  • Thumbnail for Cholinesterase inhibitor
    stimulating the muscarinic receptor, for example pilocarpine, or by inhibiting the enzyme acetylcholinesterase, which hydrolyses the acetylcholine in the...
    13 KB (1,107 words) - 04:21, 2 November 2024
  • antagonist, is a medication which functions as a leukotriene-related enzyme inhibitor (arachidonate 5-lipoxygenase) or leukotriene receptor antagonist (cysteinyl...
    10 KB (1,070 words) - 02:56, 18 April 2024
  • angiotensin converting enzyme (ACE) inhibitors in regulating blood pressure. This led to the development of captopril, the first ACE inhibitor. When the adverse...
    27 KB (3,409 words) - 06:47, 3 June 2024
  • Thumbnail for Acetylcholinesterase inhibitor
    Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter...
    26 KB (2,387 words) - 03:29, 21 August 2024
  • Thumbnail for Mixed inhibition
    Mixed inhibition (category Enzyme inhibitors)
    Mixed inhibition is a type of enzyme inhibition in which the inhibitor may bind to the enzyme whether or not the enzyme has already bound the substrate...
    8 KB (1,086 words) - 20:20, 28 October 2024
  • Thumbnail for Dopamine
    crossing the blood–brain barrier. It is often co-administered with an enzyme inhibitor of peripheral decarboxylation such as carbidopa or benserazide, to...
    139 KB (14,251 words) - 21:28, 21 November 2024
  • Thumbnail for Bradykinin
    angiotensin-converting enzyme (ACE) inhibitor drugs. It is thought that bradykinin is converted to inactive metabolites by ACE, therefore inhibition of this enzyme leads...
    20 KB (2,007 words) - 21:03, 25 June 2024
  • An enkephalinase inhibitor is a type of enzyme inhibitor which inhibits one or more members of the enkephalinase class of enzymes that break down the endogenous...
    2 KB (113 words) - 11:07, 3 July 2022