• Thumbnail for Hyaluronidase
    Hyaluronidases are a family of enzymes that catalyse the degradation of hyaluronic acid. Karl Meyer classified these enzymes in 1971, into three distinct...
    34 KB (3,092 words) - 05:38, 14 September 2024
  • Pertuzumab/trastuzumab/hyaluronidase, sold under the brand name Phesgo, is a fixed-dose combination medication to treat adults with HER2-positive breast...
    12 KB (966 words) - 04:46, 15 July 2024
  • Ocrelizumab/hyaluronidase, sold under the brand name Ocrevus Zunovo, is a fixed-dose combination medication used for the treatment of multiple sclerosis...
    5 KB (238 words) - 05:09, 6 October 2024
  • Daratumumab/hyaluronidase, sold under the brand name Darzalex Faspro, is a fixed-dose combination medication for the treatment of adults with newly diagnosed...
    11 KB (954 words) - 06:56, 8 August 2024
  • Atezolizumab/hyaluronidase, sold under the brand name Tecentriq Hybreza, is a fixed-dose combination medication used for the treatment of non-small cell...
    7 KB (362 words) - 05:09, 6 October 2024
  • Thumbnail for Rituximab
    macroglobulinemia, a type of non-Hodgkin lymphoma. Rituximab in combination with hyaluronidase human, sold under the brand names Mabthera SC and Rituxan Hycela, is...
    62 KB (5,682 words) - 07:31, 24 October 2024
  • Trastuzumab/hyaluronidase, sold under the brand name Herceptin SC among others, is a fixed-dose combination medication for the treatment of HER2-overexpressing...
    11 KB (703 words) - 18:13, 27 March 2024
  • Thumbnail for Hyaluronidase deficiency
    Hyaluronidase deficiency is a condition caused by mutations in the HYAL1 gene, and is characterized by multiple soft-tissue masses.: 544  As hyaluronidase...
    3 KB (147 words) - 13:03, 4 June 2024
  • Thumbnail for Halozyme
    primarily focused on its proprietary and patented recombinant human hyaluronidase enzyme, rHuPH20. The company's development pipeline is concentrated...
    11 KB (1,003 words) - 00:57, 11 August 2024
  • Efgartigimod alfa/hyaluronidase, sold under the brand name Vyvgart Hytrulo, is a coformulation medication used for the treatment of generalized myasthenia...
    6 KB (425 words) - 07:18, 25 June 2024
  • Thumbnail for Streptococcus pyogenes
    PMID 22050223. S2CID 207441558. Starr CR, Engleberg NC (January 2006). "Role of hyaluronidase in subcutaneous spread and growth of group A streptococcus". Infection...
    41 KB (4,042 words) - 12:33, 8 October 2024
  • Thumbnail for Daratumumab
    mantle cell lymphoma. It is available in combination with hyaluronidase as daratumumab/hyaluronidase (brand name Darzalex Faspro). In May 2018, the US Food...
    22 KB (1,836 words) - 05:53, 21 September 2024
  • Thumbnail for Cutis verticis gyrata
    acid)). Two published medical journals appear to show Hyaluronidase injections (Hyaluronidase is an enzyme used to dissolve hyaluronic acid which is...
    11 KB (1,105 words) - 12:59, 2 June 2024
  • Thumbnail for Bee sting
    phospholipase A2, hyaluronidase and acid phosphatase. The three proteins in honeybee venom that are important allergens are phospholipase A2, hyaluronidase and acid...
    14 KB (1,582 words) - 19:43, 29 June 2024
  • Thumbnail for Glycocalyx
    sulphate and hyaluronan can be shed of the endothelial layer by enzymes. Hyaluronidase, hepararanse/heparinase, matrix and membrane-type matrix metalloproteases...
    19 KB (2,192 words) - 14:00, 19 October 2024
  • Thumbnail for Cancer immunotherapy
    atezolizumab and hyaluronidase-tqjs injection". DailyMed. 25 September 2024. Retrieved 5 October 2024. "FDA approves atezolizumab and hyaluronidase-tqjs". U.S...
    92 KB (12,517 words) - 05:38, 1 October 2024
  • Thumbnail for Multiple sclerosis
    relapsing MS, and SPMS in the U.S., and RRMS in Europe. Ocrelizumab/hyaluronidase was approved for medical use in the United States in September 2024...
    170 KB (18,177 words) - 00:02, 19 October 2024
  • Thumbnail for Acrosome
    placental mammals, the acrosome contains degradative enzymes (including hyaluronidase and acrosin). These enzymes break down the outer membrane of the ovum...
    4 KB (426 words) - 15:43, 1 October 2024
  • Thumbnail for HYAL1
    Hyaluronidase-1 is an enzyme that in humans is encoded by the HYAL1 gene. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly...
    17 KB (2,109 words) - 08:43, 2 November 2024
  • Thumbnail for Hyaluronic acid
    degraded by a family of enzymes called hyaluronidases. In humans, there are at least seven types of hyaluronidase-like enzymes, several of which are tumor...
    53 KB (5,716 words) - 16:44, 22 October 2024
  • Thumbnail for Alternative splicing
    instance, the figure to the right shows 3 spliceforms from the mouse hyaluronidase 3 gene. Comparing the exonic structure shown in the first line (green)...
    62 KB (7,813 words) - 05:08, 28 October 2024
  • Thumbnail for Snake
    affect the body in different ways. Almost all snake venom contains hyaluronidase, an enzyme that ensures rapid diffusion of the venom.: 243  Venomous...
    152 KB (15,151 words) - 10:28, 5 November 2024
  • administered by intravenous infusion. The fixed-dose combination ocrelizumab/hyaluronidase is administered by subcutaneous injection. It was approved by the US...
    20 KB (1,863 words) - 03:19, 17 October 2024
  • Thumbnail for Staphylococcus aureus
    fibrinogen to fibrin to cause clots which is important in skin infections. Hyaluronidase (also known as spreading factor) breaks down hyaluronic acid and helps...
    114 KB (12,720 words) - 11:18, 29 October 2024
  • Beta-N-acetylglucosaminidase - - + Beta-N-galactosaminidase - - + Sialidase - - + Beta-galactosidase - - + Beta-glucosidase - + +/- Hyaluronidase + - +...
    7 KB (712 words) - 21:42, 18 December 2023
  • bruised. Hyaluronic acid "bruising" may be treated using injections of hyaluronidase enzyme around the location. Other common medication-specific side effects...
    22 KB (2,583 words) - 05:07, 2 November 2024
  • variety of enzymes which cause damage to host tissues. Enzymes include hyaluronidase, which breaks down the connective tissue component hyaluronic acid;...
    15 KB (1,864 words) - 23:04, 27 October 2024
  • present in myasthenia gravis. It is also available coformulated with hyaluronidase. The most common side effects include respiratory tract infections,...
    17 KB (1,326 words) - 07:06, 25 June 2024
  • Thumbnail for Indian cobra
    failure or cardiac arrest. The venom components include enzymes such as hyaluronidase that cause lysis and increase the spread of the venom. Envenomation...
    46 KB (4,604 words) - 09:01, 31 October 2024
  • Thumbnail for Vespula
    subgenus of Vespula The venom of Vespula is mostly composed of antigen 5, hyaluronidase, and phospholipase.​ A high degree of similarity occurs between immunogenic...
    9 KB (738 words) - 02:00, 29 September 2024