Immunoglobulin M (IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates. IgM is the first...
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Plasma cell dyscrasias (redirect from IgM MGUS)
myeloma protein spikes representing: a) intact IgG, IgA, IgE, IgE, or IgM; b) intact IgG, IgA, IgE, IgD, or IgM plus high concentrations of a free (i.e. not...
81 KB (10,828 words) - 17:41, 12 November 2024
IgM nephropathy or immunoglobulin M nephropathy (IgMN) is a kind of idiopathic glomerulonephritis that is marked by IgM diffuse deposits in the glomerular...
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Hyper IgM syndrome is a rare primary immune deficiency disorders characterized by low or absent levels of serum IgG, IgA, IgE and normal or increased levels...
16 KB (1,719 words) - 09:42, 18 March 2024
Immunoglobulin G (redirect from (Ig)G)
suggests that IgG3 (and IgE) appear early in a response. The IgG3, though of relatively low affinity, allows IgG-mediated defences to join IgM-mediated defences...
18 KB (2,098 words) - 17:44, 10 October 2024
IGM may refer to: Initiative on Global Markets, at the University of Chicago Booth School of Business IG Metall, German metalworkers' union IGM Financial...
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Immunoglobulin D (redirect from IgD)
where it is usually co-expressed with another cell surface antibody called IgM. IgD is also produced in a secreted form that is found in very small amounts...
17 KB (2,096 words) - 15:53, 6 April 2024
Isolated primary immunoglobulin M deficiency is a poorly defined dysgammaglobulinemia characterized by decreased levels of IgM while levels of other immunoglobulins...
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Anti-immunoglobulin (redirect from Anti-IgE)
needed] Anti-antibodies for human purposes are able to recognize IgM, IgA, IgE, IgD, and IgG. To detect all isotypes of human antibodies, anti-human kappa...
27 KB (1,724 words) - 16:00, 22 April 2024
levels of monoclonal IgA, IgG, free κ light chains, or free λ light chains are extremely high in patients with non-IgM MGUS, non-IgM smoldering multiple...
29 KB (3,074 words) - 01:49, 14 November 2024
Fc receptor (redirect from IgE receptor)
signaling chains. Another receptor can also bind IgA, although it has higher affinity for another antibody called IgM. This receptor is called the Fc-alpha/mu...
42 KB (4,735 words) - 21:19, 8 October 2024
shows mesangial deposition of IgA often with C3 and properdin and smaller amounts of other immunoglobulins (IgG or IgM). Early components of the classical...
29 KB (3,482 words) - 09:34, 27 July 2024
I. G. Farbenindustrie AG ("dye industry syndicate"), commonly known as IG Farben, was a German chemical and pharmaceutical conglomerate. It was formed...
75 KB (7,115 words) - 18:59, 5 November 2024
Immunoglobulin A (redirect from IgA)
by polymorphonuclear leukocytes. Unlike IgM and IgG, which activate complement through the classical pathway, IgA can activate complement via the alternative...
23 KB (2,589 words) - 01:00, 27 October 2024
attached as fixed test lines. It separately identifies IgM and IgG antibodies. IgM shows recent infection; IgG signifies remote infection.[citation needed] The...
96 KB (10,675 words) - 03:23, 26 October 2024
the IgG component. This differentiation of antibody classes is important as it allows for the distinction of a recent (IgM) from an old infection (IgG)...
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Selective immunoglobulin A deficiency (redirect from Selective IgA deficiency)
tract. It is defined as an undetectable serum IgA level in the presence of normal serum levels of IgG and IgM, in persons older than 4 years. It is the most...
17 KB (1,773 words) - 07:44, 20 April 2024
Immunoglobulin class switching (redirect from Ig class switching)
immunoglobulin from one type to another, such as from the isotype IgM to the isotype IgG. During this process, the constant-region portion of the antibody...
14 KB (1,530 words) - 10:33, 15 February 2024
treatment. In contrast to IgG, IgM antibodies can be used to detect acute infection but generally not chronic infection. The IgM antibodies appear sooner...
132 KB (14,650 words) - 15:58, 2 November 2024
infections and low antibody levels, specifically in immunoglobulin (Ig) types IgG, IgM, and IgA. Symptoms generally include high susceptibility to pathogens...
35 KB (3,368 words) - 21:13, 24 September 2024
immunoglobulins, which are IgA, IgE and IgG. There are 5 types of hypergammaglobulinemias associated with hyper IgM. MeSH considers hyper IgM syndrome to be a form...
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example, most antigens prompt seroconversion for the IgM class of antibodies first, and subsequently the IgG class. Seroconversion rates are one of the methods...
60 KB (7,057 words) - 01:44, 14 November 2024
measure one of two types of antibodies: immunoglobulin M (IgM) and immunoglobulin G (IgG). IgM is produced in high quantities shortly after a person is...
14 KB (1,453 words) - 11:21, 25 March 2024
is an Immunoglobulin E (IgE) mediated immediate reaction; type II, an antibody-mediated reaction mainly involving IgG or IgM; type III, an immune complex-mediated...
21 KB (1,860 words) - 04:32, 30 October 2024
Joining (J) chain is a protein component that links monomers of antibodies IgM and IgA to form polymeric antibodies capable of secretion. The J chain is well...
20 KB (2,375 words) - 10:22, 3 December 2023
antigens. It is common for D-negative individuals not to have any anti-D IgG or IgM antibodies, because anti-D antibodies are not usually produced by sensitization...
57 KB (6,439 words) - 19:41, 12 November 2024
any isotype of immunoglobulins; i.e., IgA, IgG, IgM, IgE, IgD. RF is tested by collecting blood in a plain tube (5 mL is often enough). The serum is tested...
11 KB (1,205 words) - 08:02, 5 June 2024
based on anti-human antibodies binding to human antibodies, commonly IgG or IgM. These anti-human antibodies are produced by plasma cells of non-human...
14 KB (1,669 words) - 16:51, 14 December 2023
characterized by having high levels of a circulating antibody, immunoglobulin M (IgM), which is made and secreted by the cells involved in the disease. Waldenström...
59 KB (5,773 words) - 01:40, 24 October 2024