• very wide interleukin-1 receptor (IL-1R) family are characterized by extracellular immunoglobulin-like domains and intracellular Toll/Interleukin-1R (TIR)...
    13 KB (1,572 words) - 21:44, 19 February 2023
  • Interleukin-1 receptor (IL-1R) is a cytokine receptor which binds interleukin 1. Two forms of the receptor exist. The type I receptor is primarily responsible...
    3 KB (244 words) - 17:53, 24 January 2023
  • Thumbnail for Interleukin-1 family
    The Interleukin-1 family (IL-1 family) is a group of 11 cytokines that plays a central role in the regulation of immune and inflammatory responses to...
    49 KB (6,005 words) - 16:30, 10 June 2024
  • Thumbnail for Interleukin-1 receptor antagonist
    The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. IL-1RA was initially called the IL-1 inhibitor...
    12 KB (1,323 words) - 14:55, 7 September 2024
  • Thumbnail for Interleukin-6 receptor
    Interleukin 6 receptor (IL6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. Interleukin 6 (IL6) is a potent pleiotropic...
    11 KB (1,438 words) - 14:27, 22 December 2023
  • Thumbnail for Interleukin 10
    and resultant Thromboxane receptor activation to cause vascular endothelial and cardiac dysfunctions in mice. Interleukin 10 knockout frail mice develop...
    40 KB (4,619 words) - 05:18, 22 August 2024
  • Thumbnail for IL1RL2
    interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1...
    4 KB (603 words) - 21:06, 3 March 2023
  • Thumbnail for Interleukin 1 receptor, type II
    decoy receptor for certain cytokines that belongs to the interleukin-1 receptor family. This protein binds interleukin-1α (IL1A), interleukin-1β (IL1B)...
    11 KB (1,414 words) - 05:35, 20 September 2024
  • differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in...
    45 KB (4,194 words) - 12:36, 2 May 2024
  • Thumbnail for Interleukin 1 receptor, type I
    cytokine receptor that belongs to the interleukin-1 receptor family. This protein is a receptor for interleukin 1 alpha (IL1A), interleukin 1 beta (IL1B)...
    10 KB (1,262 words) - 03:39, 18 February 2024
  • Interleukin receptors, Type 1 and Type 2. Type 1 interleukin receptors include: Interleukin-1 receptor Interleukin-2 receptor Interleukin-3 receptor Interleukin-4...
    3 KB (248 words) - 11:20, 8 June 2024
  • Thumbnail for Interleukin-4 receptor
    The interleukin 4 receptor is a type I cytokine receptor. It is a heterodimer, that is, composed of two subunits. IL4R is the human gene coding for IL-4Rα...
    7 KB (781 words) - 08:35, 20 August 2024
  • Thumbnail for Interleukin-3 receptor
    The interleukin-3 receptor (CD123) is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune...
    2 KB (206 words) - 15:30, 8 September 2024
  • Thumbnail for Interleukin-7 receptor
    The interleukin-7 receptor is a protein found on the surface of cells. It is made up of two different smaller protein chains - i.e. it is a heterodimer...
    6 KB (550 words) - 00:43, 19 August 2023
  • Thumbnail for Interleukin 4
    fibrosis. The receptor for interleukin-4 is known as the IL-4Rα. This receptor exists in 3 different complexes throughout the body. Type 1 receptors are composed...
    19 KB (2,293 words) - 11:05, 8 March 2024
  • Thumbnail for Interleukin 5
    Interleukin 5 (IL-5) is an interleukin produced by type-2 T helper cells and mast cells. Through binding to the interleukin-5 receptor, interleukin 5...
    13 KB (1,523 words) - 19:27, 26 June 2024
  • Thumbnail for Interleukin-17 receptor
    Interleukin-17 receptor (IL-17R) is a cytokine receptor which belongs to new subfamily of receptors binding proinflammatory cytokine interleukin 17A, a...
    21 KB (2,139 words) - 19:25, 2 April 2024
  • Thumbnail for Interleukin 23
    (IL-23p19) subunit. IL-23 is part of the IL-12 family of cytokines. The functional receptor for IL-23 (the IL-23 receptor) consists of a heterodimer between IL-12Rβ1...
    20 KB (2,192 words) - 23:02, 27 November 2023
  • Interleukin-28 receptor is a type II cytokine receptor found largely in epithelial cells. It binds type 3 interferons, interleukin-28 A (Interferon lambda...
    10 KB (1,126 words) - 20:57, 24 June 2021
  • The interleukin-8 receptors (IL-8R) are two 7-transmembrane proteins in the G-protein coupled-receptor family: interleukin-8 receptor A (IL-8RA) and interleukin-8...
    8 KB (963 words) - 00:05, 3 April 2024
  • Thumbnail for IL18R1
    IL18R1 (category Immunoglobulin superfamily cytokine receptors)
    this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential...
    10 KB (1,003 words) - 18:32, 14 August 2023
  • Thumbnail for Toll-interleukin receptor
    toll-interleukin-1 receptor (TIR) homology domain is an intracellular signaling domain found in MyD88, SARM1, interleukin-1 receptors, toll receptors and...
    8 KB (839 words) - 21:44, 4 April 2024
  • interleukin-5 receptor is a type I cytokine receptor. It is a heterodimer of the interleukin 5 receptor alpha subunit and CSF2RB. The IL-5 receptor (IL-5R)...
    7 KB (848 words) - 11:49, 13 January 2024
  • Thumbnail for Interleukin 12
    response to antigenic stimulation. IL-12 belongs to the family of interleukin-12. IL-12 family is unique in comprising the only heterodimeric cytokines...
    14 KB (1,578 words) - 14:00, 26 February 2024
  • Thumbnail for IL1RL1
    Interleukin 1 receptor-like 1, also known as IL1RL1 and ST2, is a protein that in humans is encoded by the IL1RL1 gene. IL1RL1 is a member of the Toll-like...
    18 KB (2,424 words) - 23:12, 19 March 2024
  • Thumbnail for Interleukin 36 receptor antagonist
    Interleukin 36 receptor antagonist (IL-36RA) is a member of the interleukin-36 family of cytokines. It was previously named Interleukin-1 family member...
    12 KB (1,151 words) - 00:55, 29 March 2023
  • Thumbnail for Interleukin 1-alpha
    Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene. In...
    22 KB (2,679 words) - 06:27, 13 September 2024
  • Thumbnail for Interleukin 1 beta
    Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and...
    26 KB (3,273 words) - 13:58, 26 August 2024
  • Thumbnail for Interleukin 2
    Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5–16 kDa protein that regulates the activities...
    43 KB (5,000 words) - 12:13, 15 September 2024
  • Thumbnail for Interleukin-7 receptor-α
    Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (Cluster of Differentiation 127) is a protein that in humans is encoded by the IL7R gene...
    6 KB (840 words) - 23:23, 20 February 2024