• Thumbnail for Interleukin 17
    Interleukin 17 family (IL17 family) is a family of pro-inflammatory cystine knot cytokines. They are produced by a group of T helper cell known as T helper...
    35 KB (3,989 words) - 13:32, 13 July 2024
  • Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes)...
    45 KB (4,194 words) - 12:36, 2 May 2024
  • Thumbnail for Interleukin-17 receptor
    Interleukin-17 receptor (IL-17R) is a cytokine receptor which belongs to new subfamily of receptors binding proinflammatory cytokine interleukin 17A, a...
    21 KB (2,139 words) - 19:25, 2 April 2024
  • Thumbnail for Interleukin 6
    Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the...
    63 KB (7,473 words) - 11:32, 1 September 2024
  • Thumbnail for Interleukin 1 beta
    Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and...
    26 KB (3,273 words) - 13:58, 26 August 2024
  • T helper 17 cells (Th17) are a subset of pro-inflammatory T helper cells defined by their production of interleukin 17 (IL-17). They are related to T regulatory...
    31 KB (3,564 words) - 14:56, 3 December 2023
  • Thumbnail for Interleukin-17A
    Interleukin-17A is a protein that in humans is encoded by the IL17A gene. In rodents, IL-17A used to be referred to as CTLA8, after the similarity with...
    53 KB (6,247 words) - 19:58, 2 April 2024
  • Thumbnail for Interleukin 23
    Interleukin 23 (IL-23) is a heterodimeric cytokine composed of an IL-12B (IL-12p40) subunit (which is shared with IL-12) and an IL-23A (IL-23p19) subunit...
    20 KB (2,192 words) - 23:02, 27 November 2023
  • Thumbnail for Interleukin 11
    Interleukin 11 (IL-11 or adipogenesis inhibitory factor) is a protein that in humans is encoded by the IL11 gene. IL-11 is a cytokine that was first isolated...
    22 KB (2,510 words) - 04:11, 12 August 2024
  • Thumbnail for Interleukin-1 family
    The Interleukin-1 family (IL-1 family) is a group of 11 cytokines that plays a central role in the regulation of immune and inflammatory responses to...
    49 KB (6,005 words) - 16:30, 10 June 2024
  • Thumbnail for Interleukin 4
    The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells...
    19 KB (2,293 words) - 11:05, 8 March 2024
  • Thumbnail for Interleukin 12
    Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, helper T cells and human B-lymphoblastoid...
    14 KB (1,578 words) - 14:00, 26 February 2024
  • form of a humanized monoclonal antibody. The substance acts by binding interleukin 17A and neutralizing it, reducing inflammation. The most common side...
    16 KB (1,451 words) - 18:24, 2 August 2024
  • Thumbnail for IL17RA
    Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217), is a human gene. Interleukin 17A (IL17A)is a proinflammatory...
    6 KB (855 words) - 11:39, 4 March 2023
  • Thumbnail for Interleukin 2
    Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5–16 kDa protein that regulates the activities...
    43 KB (5,000 words) - 12:13, 15 September 2024
  • Thumbnail for Interleukin-1 receptor antagonist
    The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. IL-1RA was initially called the IL-1 inhibitor...
    12 KB (1,323 words) - 14:55, 7 September 2024
  • Thumbnail for Psoriasis
    interferon-γ and interleukin-17. Interleukin-23 is known to induce the production of interleukin-17 and interleukin-22. Interleukin-22 works in combination...
    116 KB (13,059 words) - 13:20, 22 September 2024
  • Thumbnail for Interleukin 23 subunit alpha
    two subunits of the cytokine Interleukin-23. Interleukin-23 (IL-23) is a heterodimeric cytokine composed of an Interleukin 23 alpha subunit and an IL-12p40...
    11 KB (1,358 words) - 17:09, 6 September 2023
  • Thumbnail for Interleukin 5
    Interleukin 5 (IL-5) is an interleukin produced by type-2 T helper cells and mast cells. Through binding to the interleukin-5 receptor, interleukin 5...
    13 KB (1,523 words) - 19:27, 26 June 2024
  • Thumbnail for Secukinumab
    ankylosing spondylitis, and psoriatic arthritis. It binds to the protein interleukin (IL)-17A and is marketed by Novartis. Secukinumab is used to treat psoriasis...
    17 KB (1,245 words) - 14:04, 2 September 2024
  • Thumbnail for Interleukin 18
    Interleukin-18 (IL-18), also known as interferon-gamma inducing factor is a protein which in humans is encoded by the IL18 gene. The protein encoded by...
    18 KB (2,082 words) - 08:54, 18 March 2024
  • Thumbnail for IL17RD
    Interleukin 17 receptor D (also known as Sef) is a protein that in humans is encoded by the IL17RD gene. This gene encodes a membrane protein belonging...
    10 KB (1,360 words) - 13:56, 17 February 2024
  • Thumbnail for Interleukin 8
    Interleukin 8 (IL-8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells,...
    22 KB (2,786 words) - 02:02, 19 August 2024
  • Thumbnail for Interleukin 15
    Interleukin-15 (IL-15) is a protein that in humans is encoded by the IL15 gene. IL-15 is an inflammatory cytokine with structural similarity to Interleukin-2...
    39 KB (4,458 words) - 06:59, 3 June 2024
  • with other treatments. Brodalumab binds to the interleukin-17 receptor and so prevents interleukin 17 (IL-17) from activating the receptor. This mechanism...
    9 KB (616 words) - 03:20, 14 August 2024
  • Thumbnail for IL2RA
    The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2...
    23 KB (2,548 words) - 17:16, 27 August 2024
  • Thumbnail for Interleukin 10
    Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans, interleukin 10 is...
    40 KB (4,619 words) - 05:18, 22 August 2024
  • Thumbnail for Interleukin-12 subunit beta
    beta of interleukin 12 (also known as IL-12B, natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor p40, or interleukin-12 subunit...
    10 KB (1,383 words) - 03:56, 13 August 2023
  • Thumbnail for Interleukin 1-alpha
    Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene. In...
    22 KB (2,679 words) - 06:27, 13 September 2024
  • IL-17 or IL 17 may refer to: Interleukin 17, a pro-inflammatory cytokine Illinois's 17th congressional district Illinois Route 17 This disambiguation page...
    207 bytes (58 words) - 07:04, 24 January 2024