• Thumbnail for Kinase
    In biochemistry, a kinase (/ˈkaɪneɪs, ˈkɪneɪs, -eɪz/) is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating...
    34 KB (3,807 words) - 19:38, 18 August 2024
  • Mitogen-activated protein kinase kinase kinase kinase (MAP4K) is a family of proteins involved in cellular signal transduction. MAP4K1 (aka HPK1) MAP4K2...
    880 bytes (84 words) - 18:46, 3 April 2021
  • Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase. Subsequently...
    11 KB (1,345 words) - 09:11, 2 January 2024
  • Thumbnail for Creatine kinase
    Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme (EC 2.7.3.2) expressed by various tissues and...
    16 KB (1,765 words) - 20:23, 29 July 2024
  • Thumbnail for Protein kinase A
    In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA...
    27 KB (2,665 words) - 17:03, 6 April 2024
  • Thumbnail for Tyrosine kinase
    A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to the tyrosine residues of specific proteins inside a cell. It functions as...
    43 KB (5,251 words) - 10:44, 24 June 2024
  • Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. They...
    9 KB (974 words) - 14:46, 22 June 2024
  • Thumbnail for Receptor tyrosine kinase
    unique tyrosine kinase genes identified in the human genome, 58 encode receptor tyrosine kinase proteins. Receptor tyrosine kinases have been shown not...
    28 KB (3,078 words) - 07:46, 3 June 2024
  • Thumbnail for Protein kinase
    protein kinase is a kinase which selectively modifies other proteins by covalently adding phosphates to them (phosphorylation) as opposed to kinases which...
    15 KB (1,635 words) - 23:25, 13 August 2024
  • transduction MAP kinase MAP kinase kinase kinase MAP kinase kinase kinase kinase Dérijard B, et al. (1995). "Independent human MAP-kinase signal transduction...
    3 KB (296 words) - 17:06, 14 September 2023
  • Thumbnail for MTOR
    a kinase that in humans is encoded by the MTOR gene. mTOR is a member of the phosphatidylinositol 3-kinase-related kinase family of protein kinases. mTOR...
    119 KB (12,654 words) - 00:05, 31 July 2024
  • A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
    46 KB (5,492 words) - 03:05, 21 June 2024
  • kinase] kinase (EC 2.7.11.3) is an enzyme that catalyzes the chemical reaction ATP + dephospho-{[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase}...
    4 KB (411 words) - 13:47, 26 August 2023
  • Thumbnail for Pyruvate kinase
    Pyruvate kinase is the enzyme involved in the last step of glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to...
    33 KB (4,042 words) - 02:51, 1 February 2024
  • Thumbnail for Thymidylate kinase
    Thymidylate kinase (EC 2.7.4.9; dTMP kinase) catalyzes the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP)...
    4 KB (350 words) - 06:28, 29 November 2023
  • In cell biology, Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling...
    27 KB (2,716 words) - 18:23, 1 August 2024
  • Phosphatidylinositol 3-kinase-related kinases (PIKKs) are a family of Ser/Thr-protein kinases with sequence similarity to phosphatidylinositol-3 kinases (PI3Ks). The...
    2 KB (106 words) - 09:29, 23 October 2022
  • Thumbnail for AMP-activated protein kinase
    5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
    65 KB (7,147 words) - 05:41, 24 June 2024
  • Thumbnail for Pyruvate kinase deficiency
    Pyruvate kinase deficiency is an inherited metabolic disorder of the enzyme pyruvate kinase which affects the survival of red blood cells. Both autosomal...
    14 KB (1,477 words) - 04:25, 9 August 2024
  • Thumbnail for Cyclin-dependent kinase
    Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
    35 KB (3,829 words) - 14:24, 17 June 2024
  • Thumbnail for Phosphoinositide 3-kinase
    Phosphoinositide 3-kinases (PI3Ks), also called phosphatidylinositol 3-kinases, are a family of enzymes involved in cellular functions such as cell growth...
    32 KB (3,463 words) - 17:34, 20 November 2023
  • Rhodopsin kinase (EC 2.7.11.14, rod opsin kinase, G-protein-coupled receptor kinase 1, GPCR kinase 1, GRK1, opsin kinase, opsin kinase (phosphorylating)...
    12 KB (1,405 words) - 01:32, 4 March 2023
  • or CCaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes. CAMKs are activated by increases in the concentration...
    8 KB (886 words) - 12:46, 31 January 2024
  • Thumbnail for Thymidine kinase
    Thymidine kinase is an enzyme, a phosphotransferase (a kinase): 2'-deoxythymidine kinase, ATP-thymidine 5'-phosphotransferase, EC 2.7.1.21. It can be found...
    103 KB (11,263 words) - 23:00, 25 July 2024
  • Thumbnail for RAF kinase
    RAF kinases are a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes. The mouse sarcoma virus 3611 contains...
    5 KB (556 words) - 08:06, 3 June 2024
  • Thumbnail for Tyrosine kinase inhibitor
    A tyrosine kinase inhibitor (TKI) is a pharmaceutical drug that inhibits tyrosine kinases. Tyrosine kinases are enzymes responsible for the activation...
    10 KB (1,179 words) - 18:31, 8 August 2024
  • Thumbnail for Serine/threonine-specific protein kinase
    A serine/threonine protein kinase (EC 2.7.11.-) is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid...
    14 KB (1,210 words) - 13:35, 14 June 2024
  • Thumbnail for MAP4K1
    Mitogen-activated protein kinase kinase kinase kinase 1 is a protein kinase that in humans is encoded by the MAP4K1 gene. It is also known as HPK1 (Hematopoietic...
    5 KB (559 words) - 10:37, 22 December 2023
  • nucleotide kinase is any kinase taking a nucleotide reactant. It may mean: Nucleoside-phosphate kinase, EC 2.7.4.4 Nucleoside-diphosphate kinase, EC 2.7...
    353 bytes (92 words) - 13:44, 19 October 2021
  • proteins, such as mitogen-activated protein kinases (MAPKs), originally called extracellular signal-regulated kinases (ERKs), which communicate by adding phosphate...
    24 KB (3,068 words) - 07:21, 7 June 2024