family involved in the degradation of the extracellular matrix. In humans the MMP9 gene encodes for a signal peptide, a propeptide, a catalytic domain with...

concentrations show a significant increased cytotoxic activity and suppress COX-2 and MMP9 gene expression in both cell culture and colon tissue, suggest the anti-inflammatory...

of ages 76 to 80 years. Epitalon appears to inhibit the synthesis of the MMP9 protein in vitro in aging skin fibroblasts. An in vivo study in aging mice...

The hemopexin-like C-terminal domain of MMP9 PDB 1itv...

beta, interleukin 6, tumor necrosis factor alpha (TNF alpha), MMP1, MMP2, MMP9, prostaglandin E2, complement system, reactive oxygen species (ROS), and...

to aortic dissection and aneurysm. However, other studies have also shown MMP9 involvement with no differences in TIMP expression. The size of the proximal...

PMC 6289486. PMID 30546844. Turner RJ, Sharp FR (2016-03-04). "Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following...

collagen synthesis and fibrosis of the heart. Increase expression of MMP1 and MMP9 led to degradation of collagen fibres, and subsequently dilatation of the...

of growth factors and are required for tumor metastasis and angiogenesis. MMP9 is associated with the bone microenvironment. It is expressed by osteoclasts...

Additionally, in KRT81-knockdown MDA-MB231 cells, zymography illustrated decreased MMP9 activity, while scratch and invasion assays demonstrated diminished cell...

active site zinc. Examples of enzymes that ilomastat inhibit include rabbit MMP9, thermolysin, peptide deformylase, and anthrax lethal factor endopeptidase...

against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration into tumours...

to be activated in a protease-dependent or independent manner. MMP2 and MMP9 are select TGF-β activators and ligands and are found in higher levels in...

HGNC:7173 P08254 9660 MMP7 HGNC:7174 P09237 9661 MMP8 HGNC:7175 P22894 9662 MMP9 HGNC:7176 P14780 9663 MMP10 HGNC:7156 P09238 9664 MMP11 HGNC:7157 P24347...

Baumann PS, Klauser P, Conus P, Tirouvanziam R, Cuenod M (November 2020). "MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation...

Shimizu D, et al. (May 2011). "Ranpirnase Interferes with NF-κB Pathway and MMP9 Activity, Inhibiting Malignant Mesothelioma Cell Invasiveness and Xenograft...

Oi Y, Milewicz DM (*Authors contribution equal). Association of MMP2 and MMP9 polymorphisms with intracranial aneurysms. J Neurosurg. 105(3):418-23, 2006...

This resulted in cells being promoted to enter S phase more rapidly ROCK-1 MMP9: necessary for ECM regulation FMNL3: a Formin downstream target, which is...

(February 2011). "Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic...

expressed are matrix metalloproteinases MMP2 and MMP9. Additionally, gelatinases A (MMP2) and B (MMP9) have been proven to assist in developing new blood...

phosphorylation. This can then trigger expression of matrix metalloproteinase 9 (MMP9). MMP9 can degrade proteins in the extracellular matrix, which aids in the priming...

angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP9). Along with its main oncogene function in hepatocellular carcinoma (HCC)...

upregulating the expression of matrix metalloproteinases (MMPs) MMP2 and MMP9 in ovarian cancer. Contrary to previously mentioned cancers, the amount of...

angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP9). MTDH acts as an oncogene in melanoma, malignant glioma, breast cancer and...

Lactoferrin, Lipoprotein lipase, LPL, MAPK8IP1, MAPK8IP2, Midkine, MMP13, MMP2, MMP9, Neuroserpin, Nexin-1, NOS1AP, PAI 2, PAI-1, PDGF, tPA, uPA, Polymyxin B...

induction of prometastatic and angiogenic factors like CCL2, Cox-2, MMP2, MMP9 and VEGF. Furthermore mS100a7a15 recruits tumor-associated-macrophages (TAM)...

MMP7 has a shallow hydrophobic substrate-binding pocket. In contrast to MMP9 which has the longest hinge, MMP7 lacks hemopexin and does not have a hinge...

Ronkainen A, Juvonen T, Kuivaniemi H (Nov 1999). "Genetic analysis of MMP3, MMP9, and PAI-1 in Finnish patients with abdominal aortic or intracranial aneurysms"...

this protein family) matrix metalloproteinases: MMP1, MMP2, MMP3, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13, MMP14, MMP15, MMP16, MMP17, MMP19, MMP20, MMP21...

encoding proteins containing this domain include: MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP12, MMP13, MMP14, MMP15, MMP16, MMP17, MMP19, MMP20, MMP21, MMP24...