• Thumbnail for Phenylethanolamine N-methyltransferase
    Phenylethanolamine N-methyltransferase (PNMT) is an enzyme found primarily in the adrenal medulla that converts norepinephrine (noradrenaline) to epinephrine...
    16 KB (1,894 words) - 10:01, 27 March 2024
  • N-methyltransferase Nicotinate N-methyltransferase Phenylethanolamine N-methyltransferase Phosphatidylethanolamine N-methyltransferase Phosphatidyl-N-methylethanolamine...
    1 KB (161 words) - 09:09, 3 September 2016
  • Thumbnail for Catecholamine
    the human brain which express its synthesizing enzyme, phenylethanolamine N-methyltransferase; these neurons project from a nucleus that is adjacent (ventrolateral)...
    20 KB (2,075 words) - 08:55, 17 July 2024
  • Thumbnail for Methyltransferase
    "PNMT phenylethanolamine N-methyltransferase". NCBI Genetic Testing Registry. Retrieved 18 February 2014. "HNMT histamine N-methyltransferase". NCBI...
    26 KB (2,911 words) - 18:43, 22 October 2024
  • Thumbnail for Hydralazine
    Retrieved 26 February 2017. Singh V, Sharma P, Capalash N (May 2013). "DNA methyltransferase-1 inhibitors as epigenetic therapy for cancer". Current Cancer...
    16 KB (1,332 words) - 03:59, 30 September 2024
  • Thumbnail for N-Methyltyramine
    N-methylation of tyramine via the action of the enzyme phenylethanolamine N-methyltransferase in humans and tyramine N-methyltransferase in plants. N-methyltyramine...
    15 KB (2,028 words) - 10:07, 21 October 2024
  • Thumbnail for N-Methylphenethylamine
    in human urine (<1 μg over 24 hours) and is produced by phenylethanolamine N-methyltransferase with phenethylamine as a substrate, which significantly...
    10 KB (1,125 words) - 02:12, 22 April 2024
  • Thumbnail for Phenylethanolamine
    Phenylethanolamine (sometimes abbreviated PEOH), or β-hydroxyphenethylamine, is a trace amine with a structure similar to those of other trace phenethylamines...
    14 KB (1,633 words) - 08:11, 1 September 2024
  • Thumbnail for Adrenaline
    adrenaline secretion as the activity of the synthesizing enzyme, phenylethanolamine-N-methyltransferase, depends on the high concentration of cortisol that drains...
    57 KB (6,576 words) - 08:23, 29 October 2024
  • Thumbnail for Catechol-O-methyltransferase
    Catechol-O-methyltransferase (COMT; EC 2.1.1.6) is one of several enzymes that degrade catecholamines (neurotransmitters such as dopamine, epinephrine...
    29 KB (3,236 words) - 00:14, 10 July 2024
  • Thumbnail for Mepacrine
    the protozoan's cell membrane. It is known to act as a histamine N-methyltransferase inhibitor. It also inhibits NF-κB and activates p53. Mepacrine was...
    14 KB (1,455 words) - 16:11, 7 August 2024
  • Thumbnail for Dopaminergic
    deficits associated with schizophrenia: potential role of catechol-O-methyltransferase inhibitors". CNS Drugs. 21 (7): 535–557. doi:10.2165/00023210-200721070-00002...
    28 KB (2,798 words) - 23:11, 22 October 2024
  • the metabolites undergo N-methylation by non-specific N-methyltransferase(NMT) or by phenylethanolamine-N-methyltransferase (PNMT) (found in the adrenal...
    25 KB (2,877 words) - 22:38, 8 December 2023
  • Thumbnail for Adderall
    dopamine as well. In turn, N-methylphenethylamine is metabolized from phenethylamine by phenylethanolamine N-methyltransferase, the same enzyme that metabolizes...
    58 KB (21,550 words) - 19:20, 8 October 2024
  • Thumbnail for Diphenhydramine
    The drug has also been found to act as an inhibitor of histamine N-methyltransferase (HNMT). Oral bioavailability of diphenhydramine is in the range of...
    68 KB (6,188 words) - 17:09, 1 November 2024
  • Thumbnail for Adrenal gland
    noradrenaline is converted to epinephrine by the enzyme phenylethanolamine N-methyltransferase (PNMT) and stored in granules. Glucocorticoids produced...
    49 KB (5,621 words) - 09:47, 5 November 2024
  • Thumbnail for Dopamine
    Norepinephrine is converted into epinephrine by the enzyme phenylethanolamine N-methyltransferase with S-adenosyl-L-methionine as the cofactor. Some of the...
    139 KB (14,249 words) - 08:58, 4 November 2024
  • Thumbnail for Tyramine
    and salts of isomers where they exist, means that meta-tyramine and phenylethanolamine, a substance found in every living human body, and other common, non-hallucinogenic...
    28 KB (2,685 words) - 08:23, 5 November 2024
  • Thumbnail for Phenethylamine
    of roughly 30 seconds. In humans, PEA is metabolized by phenylethanolamine N-methyltransferase (PNMT), monoamine oxidase A (MAO-A), monoamine oxidase B...
    46 KB (4,510 words) - 12:55, 16 October 2024
  • N-methyltransferase (NMT) [22] and phenylethanolamine N-methyltransferase (PNMT) [23] to the corresponding secondary amines (e.g. synephrine [14], N...
    8 KB (1,436 words) - 17:54, 28 December 2023
  • Thumbnail for Norepinephrine
    Norepinephrine (category Phenylethanolamines)
    can further be converted into epinephrine by the enzyme phenylethanolamine N-methyltransferase with S-adenosyl-L-methionine as cofactor. In mammals, norepinephrine...
    59 KB (6,525 words) - 20:37, 31 October 2024
  • Thumbnail for List of adrenergic drugs
    Hexoprenaline Higenamine Indacaterol Isoetarine Isoprenaline (isoproterenol) N-Isopropyloctopamine Isoxsuprine Labetalol Levonordefrin Levosalbutamol Mabuterol...
    17 KB (988 words) - 14:32, 27 March 2024
  • Thumbnail for Amphetamine
    dopamine as well. In turn, N-methylphenethylamine is metabolized from phenethylamine by phenylethanolamine N-methyltransferase, the same enzyme that metabolizes...
    274 KB (28,856 words) - 03:42, 2 November 2024
  • Thumbnail for Oudenone
    Nepicastat Phenopicolinic acid Tropolone Zamicastat PNMTTooltip Phenylethanolamine N-methyltransferase Substrates→Products: Norepinephrine (noradrenaline)→Epinephrine...
    2 KB (69 words) - 19:25, 16 August 2022
  • Thumbnail for Methylene blue
    284–287. doi:10.1016/j.afjem.2020.06.014. PMC 7700985. PMID 33299766. Aggarwal N, Kupfer Y, Seneviratne C, Tessler S (January 2013). "Methylene blue reverses...
    47 KB (5,008 words) - 04:15, 20 October 2024
  • Thumbnail for Sympathoadrenal system
    L-amino acid decarboxylase, dopamine-β-hydroxylase, and phenylethanolamine N-methyltransferase. The release of adrenocorticotropic hormone is usually regulated...
    18 KB (2,202 words) - 13:39, 9 March 2024
  • Thumbnail for Dextroamphetamine
    dopamine as well. In turn, N-methylphenethylamine is metabolized from phenethylamine by phenylethanolamine N-methyltransferase, the same enzyme that metabolizes...
    59 KB (20,581 words) - 22:24, 3 November 2024
  • Thumbnail for 9-Methyl-β-carboline
    Nepicastat Phenopicolinic acid Tropolone Zamicastat PNMTTooltip Phenylethanolamine N-methyltransferase Substrates→Products: Norepinephrine (noradrenaline)→Epinephrine...
    7 KB (553 words) - 19:38, 8 September 2024
  • Thumbnail for Monoamine neurotransmitter
    N-methyltransferase (NMT) [22] and phenylethanolamine N-methyltransferase (PNMT) [23] to the corresponding secondary amines (e.g. synephrine [14], N...
    7 KB (1,409 words) - 21:17, 11 March 2024
  • Thumbnail for Tacrine
    at the University of Sydney in 1949. It also acts as a histamine N-methyltransferase inhibitor. Tacrine was the prototypical cholinesterase inhibitor...
    9 KB (723 words) - 16:44, 12 July 2024