Phosphofructokinase-1 (PFK-1) is one of the most important regulatory enzymes (EC 2.7.1.11) of glycolysis. It is an allosteric enzyme made of 4 subunits...

Phosphofructokinase (PFK) is a kinase enzyme that phosphorylates fructose 6-phosphate in glycolysis. The enzyme-catalysed transfer of a phosphoryl group...

In enzymology, 1-phosphofructokinase (EC 2.7.1.56) is an enzyme that catalyzes the chemical reaction ATP + D-fructose 1-phosphate → ADP + D-fructose 1...

working in this way is fructose 2,6-bisphosphate, which activates phosphofructokinase 1 and increases the rate of glycolysis in response to the hormone...

Phosphofructokinase-2 (6-phosphofructo-2-kinase, PFK-2) or fructose bisphosphatase-2 (FBPase-2), is an enzyme indirectly responsible for regulating the...

1-phosphotransferase. Other names in common use include: 6-phosphofructokinase (pyrophosphate), inorganic pyrophosphate-dependent phosphofructokinase...

very potent activator of phosphofructokinase (PFK-1) that is synthesized when F6P is phosphorylated by a second phosphofructokinase (PFK2). In the liver,...

allosterically affects the activity of the enzymes phosphofructokinase 1 (PFK-1) and fructose 1,6-bisphosphatase (FBPase-1) to regulate glycolysis and gluconeogenesis...

Phosphofructokinase deficiency is a rare muscular metabolic disorder, with an autosomal recessive inheritance pattern. It is characterized as a deficiency...

gene on chromosome 21. This gene encodes the liver (L) isoform of phosphofructokinase-1, an enzyme that catalyzes the conversion of D-fructose 6-phosphate...

reaction catalyzing fructose 2,6-bisphosphate (a potent activator of phosphofructokinase-1, the enzyme that is the primary regulatory step of glycolysis) by...

one water molecule and releasing one phosphate (in glycolysis, phosphofructokinase 1 converts F6P and ATP to F1,6BP and ADP). This is also the rate-limiting...

aerobic respiration allosterically inhibit the glycolysis enzyme phosphofructokinase 1 because less pyruvate is needed to produce the same amount of ATP...

6-phosphofructokinase, muscle type is an enzyme that in humans is encoded by the PFKM gene on chromosome 12. Three phosphofructokinase isozymes exist in...

a situation that can be wasteful or even harmful to the cell. Phosphofructokinase 1 catalyzes the first committed step of glycolysis. LpxC catalyzes...

In enzymology, an ADP-specific phosphofructokinase (EC 2.7.1.146) is an enzyme that catalyzes the chemical reaction ADP + D-fructose 6-phosphate ⇌ {\displaystyle...

Enzyme 5.3.1.9 at KEGG Pathway Database. Compound C05345 at KEGG Pathway Database. Enzyme 2.7.1.11 at KEGG Pathway Database. Enzyme 3.1.3.11 at KEGG...

of glycolysis is an early reaction in the pathway catalysed by phosphofructokinase‑1 (PFK1). When ATP levels rise, ATP binds an allosteric site in PFK1...

transcription factors and phosphorylation of phosphofructokinase-2 (PFK2) which activates phosphofructokinase-1 (PFK1). Protein kinase B PI3K/AKT/mTOR pathway...

fluorocitrate are allosteric inhibitors of phosphofructokinase-1 (PFK-1), a key enzyme in glycolysis. When PFK-1 is inhibited, cells are no longer able to...

Sandell S, et al. (2016). "Unique Exercise Lactate Profile in Muscle Phosphofructokinase Deficiency (Tarui Disease); Difference Compared with McArdle Disease"...

allosterically affects the activity of the enzymes phosphofructokinase 1 (PFK-1) and fructose 1,6-bisphosphatase (FBPase-1) to regulate glycolysis and gluconeogenesis...

fructose-1,6-bisphosphate in a reaction catalysed by the enzyme phosphofructokinase 1 (PFK-1). ATP + fructose-6-phosphate → Fructose-1,6-bisphosphate + ADP...

reaction catalyzing fructose-2,6-bisphosphate (a potent activator of phosphofructokinase-1, the enzyme that is the primary regulatory step of glycolysis) by...

regulatory correlation between HSP60 and the glycolytic enzyme, 6-phosphofructokinase-1. Although not much information is available, cytoplasmic HSP60 concentrations...

Ordinarily F-2,6-BP binds to and increases the activity of phosphofructokinase 1. Phosphofructokinase-1 catalyses the addition of a phosphate to F-6-P to form...

human stem-loop binding protein and 3’hExo ternary complex, human phosphofructokinase-1, and the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer using...

glycolytic enzyme phosphofructokinase-1. J Cell Biol 216:2305-2313. (Spotlight article in Journal “Strength in numbers: Phosphofructokinase polymerization...

(May 2003). "The a-subunit of the V-type H+-ATPase interacts with phosphofructokinase-1 in humans". J. Biol. Chem. 278 (22): 20013–8. doi:10.1074/jbc.M210077200...

gyrase. Additionally, in Escherichia coli K-12 it has been noted that phosphofructokinase (PFK) exists as a dimer under aerobic conditions and as a tetramer...