inhibitors Kunitz STI protease inhibitor Classes of inhibitor mechanisms of action are: Suicide inhibitor Transition state inhibitor Protein protease...
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Protease inhibitor can refer to: Protease inhibitor (pharmacology): a class of medication that inhibits viral protease Protease inhibitor (biology): molecules...
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Map Proteases in angiogenesis Intramembrane proteases Protease inhibitor (pharmacology) Protease inhibitor (biology) TopFIND - database of protease specificity...
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(pharmacology) Protease inhibitor (biology) TopFIND – database of protease specificity, substrates, products and inhibitors MEROPS – database of protease evolutionary...
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A trypsin inhibitor (TI) is a protein and a type of serine protease inhibitor (serpin) that reduces the biological activity of trypsin by controlling...
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angiogenesis Intramembrane proteases Protease inhibitor (pharmacology) Protease inhibitor (biology) TopFIND - database of protease specificity, substrates...
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Serpin (redirect from Serine protease inhibitor)
serpin proteinase inhibitor 6 is expressed in monocytes and granulocytes and is a potent inhibitor of the azurophilic granule protease, cathepsin G". Blood...
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3C-like protease (3CLpro) or main protease (Mpro), formally known as C30 endopeptidase or 3-chymotrypsin-like protease, is the main protease found in...
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However, not all inhibitors are based on the structures of substrates. For example, the structure of another HIV protease inhibitor tipranavir is not...
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C1-inhibitor (C1-inh, C1 esterase inhibitor) is a protease inhibitor belonging to the serpin superfamily. Its main function is the inhibition of the complement...
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(pharmacology) Protease inhibitor (biology) TopFIND - database of protease specificity, substrates, products and inhibitors MEROPS - database of protease evolutionary...
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considering that changes to a few amino acids within HIV protease can render it much less visible to an inhibitor, the active site of this enzyme can change rapidly...
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PI (section Biology and medicine)
immunodeficiency Protease inhibitor (pharmacology), class of drugs used to treat or prevent infection by viruses, including HIV and Hepatitis C Protease inhibitor (biology)...
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first protease inhibitor, saquinavir. Following that discovery, other HIV protease inhibitors were designed using the same principle. The HIV protease is...
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molecular biology the protein SSI is a Subtilisin inhibitor-like which stands for Streptomyces subtilisin inhibitor. This is a protease inhibitor. These...
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non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance". Journal of Molecular Biology. 284 (2): 313–23...
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Proteinase K (redirect from Protease K)
In molecular biology, Proteinase K (EC 3.4.21.64, protease K, endopeptidase K, Tritirachium alkaline proteinase, Tritirachium album serine proteinase...
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Nirmatrelvir (category SARS-CoV-2 main protease inhibitors)
medication developed by Pfizer which acts as an orally active 3C-like protease inhibitor. It is part of a nirmatrelvir/ritonavir combination used to treat...
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Plasminogen activator inhibitor-2 (placental PAI, SerpinB2, PAI-2), a serine protease inhibitor of the serpin superfamily, is a coagulation factor that...
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In plant biology, proteinase inhibitors are a family of small proteins that serve an integral role in the plant’s defense mechanisms against herbivory...
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of these inhibitors act to block caspases, a family of cysteine proteases that play an integral role in apoptosis. Some of these inhibitors include the...
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SLPI (redirect from Secretory leukocyte protease inhibitor)
Antileukoproteinase, also known as secretory leukocyte protease inhibitor (SLPI), is an enzyme that in humans is encoded by the SLPI gene. SLPI is a highly...
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(2001). "The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin". J. Cell Biol....
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Alpha-1 antitrypsin (redirect from Alpha-1 protease inhibitor)
A protease inhibitor, it is also known as alpha1–proteinase inhibitor (A1PI) or alpha1-antiproteinase (A1AP) because it inhibits various proteases (not...
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Protease-activated receptors (PAR) are a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular...
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important inhibitors of urokinase are the serpins plasminogen activator inhibitor-1 (PAI-1) and plasminogen activator inhibitor-2 (PAI-2), which inhibit the...
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Beta-secretase 1 (redirect from BACE inhibitor)
the inhibitor, but can represent off-target effects as the livers of BACE1 knockout mice are normal. Tests in mice have indicated that BACE proteases, specifically...
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Management of HIV/AIDS (section Protease inhibitors)
reverse-transcriptase inhibitor (NNRTI), protease inhibitor (PI) or integrase inhibitors (also known as integrase nuclear strand transfer inhibitors or INSTIs) as...
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An inhibitor cystine knot (also known as ICK or Knottin) is a protein structural motif containing three disulfide bridges. Knottins are one of three folds...
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"Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine". Nature Chemical Biology. 7 (1): 22–24. doi:10.1038/nchembio.492...
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