methods of RNA splicing occur in nature; the type of splicing depends on the structure of the spliced intron and the catalysts required for splicing to occur...
38 KB (4,641 words) - 21:25, 2 September 2024
Alternative splicing, or alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single...
62 KB (7,809 words) - 17:56, 21 May 2024
ZTTK syndrome (section Role of SON in RNA Splicing)
hESCs by ensuring genes undergo RNA splicing to create a mature RNA transcript. The SON gene is required for RNA splicing of transcripts encoding the cell-cycle...
25 KB (2,954 words) - 11:16, 11 May 2024
Intron (category RNA splicing)
Exon mRNA Eukaryotic chromosome fine structure Small t intron Splicing: Alternative splicing Exitron Minor spliceosome Outron Function MicroRNA Others:...
47 KB (5,839 words) - 23:00, 11 July 2024
Small nuclear RNA (snRNA) is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic...
17 KB (2,325 words) - 21:13, 1 February 2024
mRNA transcripts, RNA-Seq can look at different populations of RNA to include total RNA, small RNA, such as miRNA, tRNA, and ribosomal profiling. RNA-Seq...
103 KB (11,098 words) - 04:11, 29 July 2024
Susan Berget (section Discovery of RNA splicing)
fellowship, she was instrumental in the research that led to the discovery of RNA splicing and split genes, which awarded Sharp the 1993 Nobel Prize in Physiology...
15 KB (1,780 words) - 06:19, 23 February 2024
Primary transcript (redirect from Heterogeneous nuclear RNA)
3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications...
21 KB (2,624 words) - 06:00, 3 September 2024
Exon (category RNA splicing)
will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing. The term exon refers to both the DNA...
13 KB (1,517 words) - 23:39, 2 April 2024
generally not considered. (For that, see Proteoforms.) Through RNA splicing mechanisms, mRNA has the ability to select different protein-coding segments...
17 KB (2,013 words) - 01:16, 4 January 2024
the protein product. The spliceosome, a protein-RNA complex located in the nucleus, catalyzes splicing in the following manner: The spliceosome recognizes...
55 KB (6,557 words) - 21:55, 24 August 2024
Spliceosome (category RNA splicing)
either sites of mRNA splicing or storage sites of mRNA splicing factors. It is now understood that nuclear speckles help concentrate splicing factors near...
22 KB (2,807 words) - 05:41, 3 September 2024
defective RNA. Splicing ribozymes catalyze RNA splicing, removing a section of RNA that contains a mutation and replacing it with well-functioning RNA. Existing...
6 KB (740 words) - 02:24, 6 August 2024
process of RNA splicing, leaving only exons, regions that will encode the protein. This exon sequence constitutes mature mRNA. Mature mRNA is then read...
49 KB (5,922 words) - 14:24, 18 August 2024
to be removed after transcription through a process termed RNA splicing. Splicing of RNA transcripts requires a highly precise and coordinated sequence...
41 KB (4,630 words) - 14:14, 22 July 2024
process, RNA splicing removes the non-coding RNA introns leaving behind the exons, which are then spliced and joined together to form the mature mRNA. Splicing...
6 KB (596 words) - 20:39, 4 September 2024
transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
65 KB (7,609 words) - 13:10, 11 September 2024
chemical structure of the RNA molecule: the addition of a 5' cap, the addition of a 3' polyadenylated tail, and RNA splicing. Such processing is vital...
11 KB (1,432 words) - 23:35, 24 July 2024
SR protein (section Splicing)
alternative pre-mRNA splicing, mRNA export, genome stabilization, nonsense-mediated decay, and translation. SR proteins alternatively splice pre-mRNA by preferentially...
27 KB (3,445 words) - 17:16, 7 August 2024
Ribozyme (redirect from Catalytic RNA)
(ribonucleic acid enzymes) are RNA molecules that have the ability to catalyze specific biochemical reactions, including RNA splicing in gene expression, similar...
42 KB (5,174 words) - 00:36, 11 September 2024
tRNAs. Whereas "normal" (cis-)splicing processes a single molecule, trans-splicing generates a single RNA transcript from multiple separate pre-mRNAs....
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SON (gene) (section Splicing process)
direct role in pre-mRNA splicing.[page needed] Splicing is the process through which pre-mRNA is transformed into mRNA. The pre-mRNA which has just been...
19 KB (2,301 words) - 04:27, 15 April 2024
Cell nucleus (redirect from Splicing speckles)
organization of the gene-expression machinery splicing snRNPs and other splicing proteins necessary for pre-mRNA processing. Because of a cell's changing requirements...
87 KB (9,885 words) - 14:38, 9 September 2024
Transfer RNA (abbreviated tRNA and formerly referred to as sRNA, for soluble RNA) is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides...
63 KB (7,572 words) - 16:45, 31 August 2024
RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR. The number of non-coding RNAs within...
68 KB (7,253 words) - 04:01, 23 June 2024
regulated pre-mRNA splicing and alternative splicing in genes essential for cell death and neuronal function. They specifically examined how splicing defects...
6 KB (520 words) - 12:02, 9 September 2024
Morpholino (section Modifying pre-mRNA splicing)
can also modify the splicing of pre-mRNA or inhibit the maturation and activity of miRNA. Techniques for targeting Morpholinos to RNAs and delivering Morpholinos...
37 KB (4,415 words) - 14:17, 28 August 2024
Housekeeping gene (section RNA splicing)
element RNA HNRPK Homo sapiens heterogeneous nuclear ribonucleoprotein K (HNRPK), transcript PABPN1 poly(A) binding protein, nuclear 1 SRSF3 splicing factor...
48 KB (4,612 words) - 23:41, 12 December 2023
Serine/arginine-rich splicing factor 1 (SRSF1) also known as alternative splicing factor 1 (ASF1), pre-mRNA-splicing factor SF2 (SF2) or ASF1/SF2 is a...
21 KB (2,574 words) - 16:59, 7 August 2024
Moreau-Gachelin F (March 2001). "Identification of an RNA binding specificity for the potential splicing factor TLS". J. Biol. Chem. 276 (9): 6807–16. doi:10...
32 KB (3,968 words) - 12:51, 13 May 2024