• Thumbnail for Recombinant DNA
    Recombinant DNA (rDNA) molecules are DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) that bring together...
    35 KB (3,892 words) - 13:12, 15 November 2024
  • Thumbnail for Asilomar Conference on Recombinant DNA
    The Asilomar Conference on Recombinant DNA was an influential conference organized by Paul Berg, Maxine Singer, and colleagues to discuss the potential...
    19 KB (2,500 words) - 08:23, 20 February 2024
  • Thumbnail for Molecular cloning
    experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms. The...
    32 KB (4,016 words) - 17:56, 20 August 2024
  • Thumbnail for DNA vaccine
    at the New York Department of Health devised a strategy to produce recombinant DNA vaccines by using genetic engineering to transform ordinary smallpox...
    77 KB (8,381 words) - 00:49, 24 July 2024
  • Recombinant DNA – a form of artificial DNA sequence Recombinant protein - artificially produced (and often purified) protein Recombinant virus – a virus...
    620 bytes (104 words) - 09:59, 15 May 2023
  • Thumbnail for Genetic engineering
    synthesising the DNA. A construct is usually created and used to insert this DNA into the host organism. The first recombinant DNA molecule was made...
    134 KB (14,252 words) - 05:41, 17 November 2024
  • Thumbnail for DNA ligase
    biology laboratories for recombinant DNA experiments (see Research applications). Purified DNA ligase is used in gene cloning to join DNA molecules together...
    23 KB (2,787 words) - 00:53, 18 June 2024
  • Thumbnail for Blue–white screen
    transformed with vectors containing recombinant DNA will produce white colonies; cells transformed with non-recombinant plasmids (i.e. only the vector) grow...
    13 KB (1,821 words) - 00:36, 3 December 2023
  • extracted from animals, such as insulin, are now more commonly produced by recombinant DNA. Biologics can refer to a wide range of biological products in medicine...
    30 KB (2,882 words) - 11:11, 23 July 2024
  • Thumbnail for Viral vector
    1972 by Paul Berg. Further development was temporarily halted by a recombinant DNA research moratorium following the Asilomar Conference and stringent...
    48 KB (5,532 words) - 12:43, 9 October 2024
  • Thumbnail for Escherichia coli
    where it has served as the host organism for the majority of work with recombinant DNA. Under favourable conditions, it takes as little as 20 minutes to reproduce...
    107 KB (11,172 words) - 06:59, 19 November 2024
  • Thumbnail for Fusion protein
    derived from each of the original proteins. Recombinant fusion proteins are created artificially by recombinant DNA technology for use in biological research...
    19 KB (2,305 words) - 05:22, 15 May 2024
  • inserted DNA and the chromosomal DNA. Gam functions to protect the DNA insert from being destroyed by native nucleases within the cell. Recombinant DNA can...
    47 KB (5,707 words) - 20:39, 24 August 2023
  • that production of monoclonal antibodies can be accomplished using recombinant DNA to create constructs capable of expression in mammalian cell culture...
    14 KB (1,787 words) - 23:05, 9 January 2024
  • discovery of restriction enzymes allows DNA to be manipulated, leading to the development of recombinant DNA technology that has many applications, for...
    55 KB (5,853 words) - 14:21, 27 September 2024
  • Thumbnail for Protein production
    such that it expresses large amounts of a recombinant gene. This includes the transcription of the recombinant DNA to messenger RNA (mRNA), the translation...
    25 KB (2,654 words) - 08:14, 28 October 2024
  • Thumbnail for David Baltimore
    contributed to immunology, virology, cancer research, biotechnology, and recombinant DNA research. He has also trained many doctoral students and postdoctoral...
    80 KB (8,318 words) - 03:04, 9 October 2024
  • Thumbnail for Erythropoietin
    thrombopoietin. Exogenous erythropoietin, recombinant human erythropoietin (rhEPO), is produced by recombinant DNA technology in cell culture and are collectively...
    31 KB (3,421 words) - 06:52, 2 November 2024
  • endonuclease can be joined regardless of the origin of the DNA. Such DNA is called recombinant DNA; DNA formed by the joining of genes into new combinations...
    25 KB (2,688 words) - 21:18, 21 November 2024
  • Thumbnail for Genetic recombination
    artificially induced in laboratory (in vitro) settings, producing recombinant DNA for purposes including vaccine development. V(D)J recombination in...
    33 KB (3,965 words) - 13:58, 18 November 2024
  • Thumbnail for Plasmid
    Plasmid (redirect from DNA plasmids)
    vectors in molecular cloning, serving to drive the replication of recombinant DNA sequences within host organisms. In the laboratory, plasmids may be...
    55 KB (6,299 words) - 03:42, 18 November 2024
  • Thumbnail for Tissue-type plasminogen activator
    PE") and leads to low blood pressure, recombinant tPA is recommended. tPA was first produced by recombinant DNA techniques at Genentech in 1982. Tissue-type...
    28 KB (3,063 words) - 04:57, 17 August 2024
  • Thumbnail for Neurogenetics
    genetics such as recombinant DNA technology and reverse genetics allowed for the broader use of DNA polymorphisms to test for linkage between DNA and gene defects...
    30 KB (3,387 words) - 18:18, 10 September 2024
  • Thumbnail for History of genetic engineering
    combining the two enzymes it was possible to "cut and paste" DNA sequences to create recombinant DNA. Plasmids, discovered in 1952, became important tools for...
    59 KB (6,419 words) - 05:18, 5 September 2024
  • Thumbnail for Genetically modified organism
    directly alter the DNA and therefore genes of organisms. In 1972, Paul Berg created the first recombinant DNA molecule when he combined DNA from a monkey virus...
    223 KB (24,627 words) - 12:34, 17 November 2024
  • Thumbnail for Paul Berg
    contributions to basic research involving nucleic acids, especially recombinant DNA. Berg received his undergraduate education at Penn State University...
    18 KB (1,423 words) - 15:53, 20 November 2024
  • Thumbnail for History of biology
    sense of genetic engineering began in the 1970s, with the invention of recombinant DNA techniques. Restriction enzymes were discovered and characterized in...
    83 KB (10,110 words) - 12:50, 11 October 2024
  • Thumbnail for DNA
    these techniques in recombinant DNA technology. Recombinant DNA is a man-made DNA sequence that has been assembled from other DNA sequences. They can...
    166 KB (17,843 words) - 13:16, 19 September 2024
  • notable proteins that are produced from recombinant DNA, using biomolecular engineering. In many cases, recombinant human proteins have replaced the original...
    22 KB (2,322 words) - 18:33, 9 February 2024
  • Thumbnail for Insulin
    diabetics before human insulin could be produced in large quantities by recombinant DNA technologies. Insulin was the first peptide hormone discovered. Frederick...
    121 KB (13,799 words) - 10:33, 13 November 2024