protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress...
41 KB (4,467 words) - 04:49, 25 July 2024
Transcription factor Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, forms the AP-1 early response...
45 KB (5,452 words) - 05:07, 13 July 2024
molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information...
75 KB (8,057 words) - 04:44, 25 July 2024
General transcription factors (GTFs), also known as basal transcriptional factors, are a class of protein transcription factors that bind to specific...
12 KB (1,317 words) - 20:08, 28 August 2023
The AP-1 binding site, also known as the AP-1 promoter site, is a DNA sequence to which AP-1 transcription factors are able to bind. The AP-1 binding...
982 bytes (113 words) - 15:58, 19 September 2022
This list of manually curated human transcription factors is taken from Lambert, Jolma, Campitelli et al. It was assembled by manual curation. More detailed...
374 KB (81 words) - 02:10, 23 September 2023
Transcription factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene. The protein encoded by this gene...
30 KB (3,444 words) - 11:07, 25 July 2024
JunD (category Transcription factors)
with ATF3, MEN1, DNA damage-inducible transcript 3 and BRCA1. AP-1 (transcription factor) GRCh38: Ensembl release 89: ENSG00000130522 – Ensembl, May 2017...
13 KB (1,561 words) - 18:02, 22 December 2023
Activating transcription factor, ATF, is a group of bZIP transcription factors, which act as homodimers or heterodimers with a range of other bZIP factors. First...
3 KB (319 words) - 04:00, 16 August 2023
Protein c-Fos (category Transcription factors)
(part of Jun family of transcription factors), resulting in the formation of AP-1 (Activator Protein-1) complex which binds DNA at AP-1 specific sites at the...
26 KB (3,991 words) - 05:29, 10 July 2024
Transformation Specific)) family is one of the largest families of transcription factors and is unique to animals. There are 28 genes in humans, 27 in the...
10 KB (1,061 words) - 13:15, 1 August 2024
JUNB (category Transcription factors)
growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'. JUNB has been shown to interact with BRCA1, and SMAD3. AP-1 (transcription factor) GRCh38:...
9 KB (1,199 words) - 17:58, 22 August 2024
Transcription factor TFIIA is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA. TFIIA is one of several general (basal)...
6 KB (638 words) - 04:56, 29 January 2023
BATF (gene) (category Transcription factors)
basic leucine zipper (bZIP) protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization...
7 KB (885 words) - 04:32, 3 January 2024
SV40 (redirect from Macaca mulatta polyomavirus 1)
of synthesis. This is done by binding (dimerization) with the AP-1 transcription factor to give a primary transcript that is 3' polyadenylated and 5'...
19 KB (2,245 words) - 11:19, 30 June 2024
Transcription factor II B (TFIIB) is a general transcription factor that is involved in the formation of the RNA polymerase II preinitiation complex (PIC)...
18 KB (2,447 words) - 01:35, 25 July 2024
T-box transcription factor T, also known as Brachyury protein, is encoded for in humans by the TBXT gene. Brachyury functions as a transcription factor within...
34 KB (3,939 words) - 23:09, 15 January 2024
ATF1 (redirect from Activating transcription factor 1)
AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene. This gene encodes an activating transcription factor, which...
11 KB (1,380 words) - 04:59, 25 July 2024
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia. They...
49 KB (4,943 words) - 01:28, 20 August 2024
Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded...
43 KB (4,822 words) - 22:18, 10 June 2024
Transcription factor II D (TFIID) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. RNA polymerase...
5 KB (593 words) - 20:14, 3 June 2022
Psychiatry. 27 (1): 624–639. doi:10.1038/s41380-021-01256-1. PMC 8960411. PMID 34453125. Hope BT (May 1998). "Cocaine and the AP-1 transcription factor complex"...
177 KB (18,939 words) - 20:08, 9 September 2024
Activating transcription factor 2, also known as ATF2, is a protein that, in humans, is encoded by the ATF2 gene. This gene encodes a transcription factor that...
19 KB (2,261 words) - 06:43, 5 December 2023
finger transcription factors or ZF-TFs, are transcription factors composed of a zinc finger-binding domain and any of a variety of transcription-factor effector-domains...
4 KB (561 words) - 07:13, 21 January 2024
sigma factor (σ factor or specificity factor) is a protein needed for initiation of transcription in bacteria. It is a bacterial transcription initiation...
20 KB (2,042 words) - 04:48, 6 January 2024
ATF4 (redirect from Activating transcription factor 4)
includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a...
15 KB (1,773 words) - 05:01, 25 July 2024
FOSB (category Transcription factors)
of the JUN family (e.g., c-Jun, JunD), thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators...
57 KB (7,191 words) - 06:17, 25 July 2024
TFAP2A (category Transcription factors)
Transcription factor AP-2 alpha (Activating enhancer binding Protein 2 alpha), also known as TFAP2A, is a protein that in humans is encoded by the TFAP2A...
24 KB (3,050 words) - 06:21, 2 January 2024
1 (NKX2-1), also known as thyroid transcription factor 1 (TTF-1), is a protein which in humans is encoded by the NKX2-1 gene. Thyroid transcription factor-1...
19 KB (2,118 words) - 19:06, 28 August 2023
the -60 position. There are several AP-1 transcription factor binding sites in the viral LTRs. The closest AP-1 binding site is bound by the Jun and...
30 KB (3,774 words) - 20:27, 1 February 2024