Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. It is responsible for the distribution of melanin pigment in mammals...

The agouti gene, the Agouti-signaling protein (ASIP) is responsible for variations in color in many species. Agouti works with extension to regulate the...

pseudoagouti. Agouti, an animal of order Rodentia it was named after Agouti-signaling protein, the protein encoded by the agouti (ASIP) gene Agouti coloration...

Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. It is synthesized in...

molecule called the agouti-signaling protein, or ASIP. This molecule interacts with MC1R, the receptor coded by extension, to block the signal for black pigment...

the hair shaft. The Agouti gene, with its dominant A allele and recessive a allele, controls the coding for agouti signaling protein (ASIP; Q865F0). The...

among Holland Lops, produces a dark orange color known as ASIP or Agouti Signaling Protein. This color is distinct from the normal light orange color. The...

absence is mediated by agouti signalling protein, which antagonizes melanocortin 1 receptor. Loss of function of agouti signalling protein can permit unmediated...

Ekenstedt, Kari J. (3 July 2020). "Atypical Genotypes for Canine Agouti Signaling Protein Suggest Novel Chromosomal Rearrangement". Genes. 11 (7): 739. doi:10...

Legrand, Romain; Tiret, Laurent (2015). "A missense mutation in the agouti signaling protein gene (ASIP) is associated with the no light points coat phenotype...

western population of fox squirrels and by a point mutation in the agouti-signaling protein gene in the southeastern population. Black morphs may also occur...

Cuniculus, formerly Agouti Agouti (coloration), fur coloration in which each hair has alternating dark and light bands Agouti-signalling protein or ASIP, a circulating...

Shriver, M. D.; Kittles, R. A. (2005). "The 8818G allele of the agouti signaling protein (ASIP) gene is ancestral and is associated with darker skin color...

Yamada T, Barsh GS, Gantz I (March 1997). "Effects of recombinant agouti-signaling protein on melanocortin action". Molecular Endocrinology. 11 (3): 274–80...

adrenocorticotropic hormone are endogenous agonists of MC1R.: 1175  Agouti signaling protein (ASIP) appears to be the only endogenous antagonist of MC1R. Synthetic...

residue at position 126 of Agouti-signaling protein. This disrupts one of the four disulphide bonds in the normal protein, altering its tertiary structure...

mutation in ASIP (agouti signaling protein) had a higher incidence of melanoma, implying that increased melanocortin-1 receptor signaling promotes melanoma...

cysteine residue at position 120 of Agouti-signaling protein. This disrupts the four disulphide bonds in the normal protein, altering its tertiary structure...

Yamada T, Barsh GS, et al. (March 1997). "Effects of recombinant agouti-signaling protein on melanocortin action". Molecular Endocrinology. 11 (3): 274–80...

1 receptor and the Agouti locus as being the cause of the black dilution trait in dogs. Instead, TYRP1 (tyrosinase related protein 1) was found to be...

Lamoreux ML, Wilson BD, Barsh GS (February 1998). "Interaction of Agouti protein with the melanocortin 1 receptor in vitro and in vivo". Genes & Development...

suggests that there is more protein-related specificity for binding MC2R. Agouti-related protein and Agouti-signaling protein are antagonist peptides to...

Yamada T, Barsh GS, Gantz I (March 1997). "Effects of recombinant agouti-signaling protein on melanocortin action". Molecular Endocrinology. 11 (3): 274–80...

depolarization of the cell. Compared to classical neurotransmitter signaling, neuropeptide signaling is more sensitive. Neuropeptide receptor affinity is in the...

stimulated by α-melanocortin stimulating hormone but inhibited by agouti signal protein. The fact that OA1 responds to melanin modifiers indicates its probable...

and targeting agents for chemotherapy. The mammalian proteins Agouti signalling peptide and Agouti related peptide are the only known mammalian examples...

AF, Reddy M, Smith GR (December 2007). "Intersubunit signaling in RecBCD enzyme, a complex protein machine regulated by Chi hot spots". Genes & Development...

metabotropic, G-protein coupled receptors (GPCRs) to initiate a second messenger signaling cascade that induces a broad, long-lasting signal. This modulation...

express MC3 and MC4 receptors. Melanocyte-inhibiting factor Agouti-related peptide Agouti signalling peptide Nelson's syndrome Katzung, Bertram G.; Masters...

Yamada T, Barsh GS, Gantz I (March 1997). "Effects of recombinant agouti-signaling protein on melanocortin action". Molecular Endocrinology. 11 (3): 274–80...