Alteplase, sold under the brand name Activase among others, is a biosynthetic form of human tissue-type plasminogen activator (t-PA). It is a thrombolytic...
26 KB (2,334 words) - 20:01, 27 August 2024
producing types of recombinant tissue plasminogen activator (rtPA) such as alteplase, reteplase, and tenecteplase. These drugs are used in clinical medicine...
28 KB (3,063 words) - 04:57, 17 August 2024
Management of Acute Ischemic Stroke supports considering tenecteplase over alteplase in patients without contraindication to intravenous thrombolytics. Distribution:...
9 KB (912 words) - 19:42, 20 December 2023
medications, such as anticoagulants and thrombolytic tpA medication (such as alteplase) which can increase the bleeding risk. Effective treatment is complex...
6 KB (567 words) - 00:52, 9 December 2023
(Kabikinase) Urokinase Recombinant tissue plasminogen activators (rtPA) Alteplase (Activase or Actilyse) Reteplase (Retavase) Tenecteplase Anistreplase...
18 KB (2,076 words) - 22:58, 23 August 2024
(alteplase), but the modifications give reteplase a longer half-life of 13–16 minutes. Reteplase also binds fibrin with lower affinity than alteplase,...
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manufactured using recombinant techniques and is sold as alteplase, reteplase, and tenecteplase. Alteplase was the first of these versions to go on the market...
9 KB (1,083 words) - 14:08, 27 January 2024
Vidara Therapeutics and finally Horizon Pharma as of 2019. Activase (alteplase), for heart attacks. Akynzeo (netupitant/palonosetron), for nausea and...
55 KB (5,124 words) - 05:32, 27 August 2024
with thrombolysis (clot dissolution) by thrombolytic medications (e.g., alteplase, reteplase), as either alternative or complement thereto. It is commonly...
11 KB (914 words) - 22:42, 14 August 2024
-arit for antiarthritic agents (e.g. lobenzarit) -ase for enzymes (e.g. alteplase) -azepam or -azolam for benzodiazepines (e.g. diazepam and alprazolam)...
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Migrainous infarction (section Alteplase)
high and therefore, treatment using streptokinase is not recommended. Alteplase is a recombinant tissue plasminogen activator which enhances the conversion...
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production. The thrombolytic medication against myocardial infarction alteplase (Activase) was approved by the US Food and Drug Administration in 1987...
17 KB (1,988 words) - 10:36, 29 June 2024
medical imaging between 4.5 hours and 9 hours or who wake up with stroke, alteplase results in some benefit. Its use is endorsed by the American Heart Association...
185 KB (20,504 words) - 06:38, 17 August 2024
Willebrand factor Other Biomarkers- PARK7, B-type neurotrophic growth factor. Alteplase (t-PA) is an effective medication for acute ischemic stroke. When given...
23 KB (2,364 words) - 09:48, 31 July 2024
embolus. Some have also recommended thrombolysis with catheter directed alteplase or mechanical thrombectomy with a large bore catheter and manual aspiration...
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tissue plasminogen activator (also known as tPA, t-PA, rtPA, Activase, or Alteplase or Actilyse) in the US and other countries, and edaravone (Radicut) in...
7 KB (742 words) - 06:16, 9 February 2024
This is achieved by the administration of a drug (such as urokinase or alteplase) that activates plasmin, an enzyme that occurs naturally in the body and...
37 KB (4,360 words) - 21:24, 10 July 2024
Abbokinase) and competes with recombinant tissue plasminogen activator (e.g., alteplase) as a thrombolytic drug. All plasminogen activators (urokinase, tPA) catalyze...
20 KB (2,290 words) - 08:54, 4 May 2024
growth hormone deficiency (ceased manufacturing 2004). 1987: Activase (alteplase): A recombinant tissue plasminogen activator (tPa) used to dissolve blood...
32 KB (2,862 words) - 04:08, 6 August 2024
and Application Consortium (QUTAC). Prescription Medicines: Actilyse (alteplase) Aggrenox (dipyridamole / acetylsalicylic acid) Alna / Flomax (tamsulosin)...
39 KB (3,272 words) - 11:00, 31 July 2024
requires thrombolysis or embolectomy. Thrombolysis can be systemic via IV alteplase (tPA) or catheter-directed. tPA works to break up the clot. A major risk...
24 KB (2,615 words) - 16:47, 29 July 2024
prompt evaluation for acute ischemic stroke and administration of IV alteplase in conjunction with Neurology. From the onset of the COVID-19 pandemic...
172 KB (19,950 words) - 12:13, 22 August 2024
KP, Hamilton S (1999). "Recombinant tissue-type plasminogen activator (alteplase) for ischemic stroke 3 to 5 hours after symptom onset: the ATLANTIS study:...
35 KB (4,263 words) - 10:53, 17 April 2024
RO, Soinne L, Toni D, Vanhooren G (January 2007). "Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis...
8 KB (904 words) - 21:14, 26 June 2024
Bivalirudin Dabigatran Edoxaban Enoxaparin Heparin Rivaroxaban Warfarin Alteplase Streptokinase Urokinase Loop diuretics: bumetanide ethacrynic acid furosemide...
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anti-platelet therapy like aspirin and clopidogrel, and thrombolytic therapy like alteplase and streptokinase. If an embolus is causing life or limb-threatening ischemia...
14 KB (1,850 words) - 21:34, 25 February 2024
Currently available thrombolytic agents include streptokinase, urokinase, and alteplase (recombinant tissue plasminogen activator, rtPA). More recently, thrombolytic...
30 KB (3,470 words) - 03:58, 25 December 2023
Iodoheparinate S01XA10 Inosine S01XA11 Nandrolone S01XA12 Dexpanthenol S01XA13 Alteplase S01XA14 Heparin S01XA15 Ascorbic acid S01XA18 Ciclosporin S01XA19 Limbal...
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combinations with proton pump inhibitors B01AD01 Streptokinase B01AD02 Alteplase B01AD03 Anistreplase B01AD04 Urokinase B01AD05 Fibrinolysin B01AD06 Brinase...
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Altamist altanserin (INN) altapizone (INN) Altebrel (INN) alteconazole (INN) alteplase (INN) Altinac altinicline (INN) altizide (INN) Altocor altoqualine (INN)...
12 KB (566 words) - 20:37, 27 August 2024