A boronic acid is an organic compound related to boric acid (B(OH)3) in which one of the three hydroxyl groups (−OH) is replaced by an alkyl or aryl group...
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groups attached to boron. Phenylboronic acid is a white powder and is commonly used in organic synthesis. Boronic acids are mild Lewis acids which are generally...
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Protodeboronation (category Boron compounds)
metal-catalysed coupling reactions that utilise boronic acids (see Suzuki reaction). For a given boronic acid, the propensity to undergo protodeboronation...
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reactions include availability of common boronic acids, mild reaction conditions, and its less toxic nature. Boronic acids are less toxic and safer for the environment...
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modern climate. Allotropes of boron Boron deficiency Boron oxide Boron nitride Boron neutron capture therapy Boronic acid Hydroboration-oxidation reaction...
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Boric acid, more specifically orthoboric acid, is a compound of boron, oxygen, and hydrogen with formula B(OH)3. It may also be called hydrogen orthoborate...
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Petasis reaction (category Chemical synthesis of amino acids)
multi-component reaction of an amine, a carbonyl, and a vinyl- or aryl-boronic acid to form substituted amines. Reported in 1993 by Nicos Petasis as a practical...
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Organoboron chemistry (redirect from Carbon-boron bond)
BRn(OR)3-n are called borinic esters (n = 2), boronic esters (n = 1), and borates (n = 0). Boronic acids are key to the Suzuki reaction. Trimethyl borate...
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Dynamic covalent chemistry (section Boronic acid)
natural systems. Boronic acid self-condensation or condensation with diols is a well-documented dynamic covalent reaction. The boronic acid condensation has...
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Chan–Evans–Lam coupling is a cross-coupling reaction between an aryl boronic acid and an alcohol or an amine to form the corresponding secondary aryl amines...
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Functional group (section Groups containing boron)
Compounds containing boron exhibit unique chemistry due to their having partially filled octets and therefore acting as Lewis acids. note 1 Fluorine is...
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cores: Vaborbactam, used in combination with meropenem (Vabomere). Has a boronic acid core. Bacteria that can produce beta-lactamases include, but are not...
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shown to conveniently detect peptides incorporating the boronic acid moiety by MALDI. Gentisic acid - Compound Summary, PubChem. Haynes, p. 5.91 Haynes,...
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organic reaction forming a new carbon–carbon bond from a thioester and a boronic acid using a metal catalyst. It is a cross-coupling reaction. This reaction...
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groups to make boronic and borinic esters. Purification of the mixtures that result from the reactions is required, as often boronic esters will also...
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carboxylic acid is an organic acid that contains a carboxyl group (−C(=O)−OH) attached to an R-group. The general formula of a carboxylic acid is often...
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Carbonyl group (redirect from Carboxylic Acid Derivatives)
classes of organic compounds (such as aldehydes, ketones and carboxylic acids), as part of many larger functional groups. A compound containing a carbonyl...
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alternatives to boronic acids (RB(OH)2), boronate esters (RB(OR′)2), and organoboranes (R3B), particularly for Suzuki-Miyaura coupling. Boronic acids RB(OH)2...
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protected aryl boronic ester which gives after acidic work-up the target product in 78% yield. The same reactants are forming with the aryl boronic ester at...
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methods are not or only conditionally usable. In addition to the organic boronic acid derivatives, which often bind highly specifically to the 1,2-diol groups...
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Nevalainen T (November 2008). "Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase". Journal of Medicinal Chemistry...
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crystal As an acid catalyst in organic synthesis As a starting material for the production of other boron compounds, such as boron carbide Boron suboxide Boric...
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Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly. Methyl ethers typically...
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forms white fumes in moist air. It is a useful Lewis acid and a versatile building block for other boron compounds. The geometry of a molecule of BF3 is trigonal...
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Ester (redirect from Carboxylic acid ester)
oxoacids (e.g. esters of acetic acid, carbonic acid, sulfuric acid, phosphoric acid, nitric acid, xanthic acid), but also from acids that do not contain oxygen...
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Borylation (category Boron)
molecules. Boronic acids, and boronic esters are common boryl groups incorporated into organic molecules through borylation reactions. Boronic acids are trivalent...
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halides, aryl halides using tetrahydroxydiboron, aryl halides using bis-boronic acid, aryl triflates, aryl mesylates, vinyl halides, vinyl halides of α,β-unsaturated...
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Ketone (section Acid/base properties of ketones)
Using very strong bases like lithium diisopropylamide (LDA, pKa of conjugate acid ~36) under non-equilibrating conditions (–78 °C, 1.1 equiv LDA in THF, ketone...
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peroxides are: Peroxy acids, the peroxy derivatives of many familiar acids, examples being peroxymonosulfuric acid and peracetic acid, and their salts, one...
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Imine (section Acid-base reactions)
carbon acids with nitroso compounds. The rearrangement of trityl N-haloamines in the Stieglitz rearrangement. By reaction of alkenes with hydrazoic acid in...
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