Cluster of differentiation 40, CD40 is a type I transmembrane protein found on antigen-presenting cells and is required for their activation. The binding...

CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules...

crucial in the IL-17 signaling pathway. Moreover, this protein is only used in cells expressing CD40 and CD40L, which are also from the tumor necrosis receptor...

to continue the immune response can come from B7-CD28 and CD40–CD40L interactions. When CD40 on the APC binds CD40L(CD154) on the T cell, signals are sent...

antigen on MHC class II proteins, a CD4+ cell will aid those cells through a combination of cell to cell interactions (e.g. CD40 (protein) and CD40L) and through...

Heat shock proteins (HSPs) are a family of proteins produced by cells in response to exposure to stressful conditions. They were first described in relation...

which codes for CD40 ligand. This gene is located on the long arm of the X chromosome at position 26, denoted Xq26. Normally, CD40 ligand is expressed...

(November 2009). "A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific...

signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester, and inflammatory cytokine TNF and IL-1, which suggests a...

as tumor necrosis factor ligand superfamily member 13 (TNFSF13), is a protein of the TNF superfamily recognized by the cell surface receptor TACI. It...

that the protein is an important component of the TGF-β induced apoptotic process. TTRAP has been shown to interact with ETS1, TNFRSF1B and CD40. This gene...

activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins. CD5 was used as a T-cell marker until monoclonal antibodies...

is a chimeric monoclonal antibody binding to the immune stimulatory protein CD40. As of 2009[update], it has not entered clinical trials. International...

homolog (DIABLO) is a mitochondrial protein that in humans is encoded by the DIABLO (direct IAP binding protein with low pI) gene on chromosome 12. DIABLO...

prion protein (PrP) is encoded in the human body by the PRNP gene also known as CD230 (cluster of differentiation 230). Expression of the protein is most...

J, Izawa K, Kambe N, Yasumi T, Nakahata T, Heike T (January 2012). "The CD40-CD40L axis and IFN-γ play critical roles in Langhans giant cell formation"...

AT-hook binding motif. The protein is expressed as different isoforms. AKNA is known to upregulate expression of the receptor CD40 and its ligand CD40L/CD154...

Human protein-coding gene pages:  •Python code for maintaining the list  •List of human protein-coding genes page 1 covers genes A1BG–EPGN  •List of human...

and mediates signaling through the nuclear factor-κB pathway, mimicking CD40 receptor signaling. It is often found in the malignant Reed–Sternberg cells...

anti-CD40 plus IL-4. The addition of anti-CD40 causes the B cells to resemble those found in the GC. Pertussis toxin inhibits the action of G proteins and...

or tumor necrosis factor receptor superfamily member 6 (TNFRSF6), is a protein that in humans is encoded by the FAS gene. Fas was first identified using...

Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the PTPRC gene. PTPRC is also known as...

several co-stimulatory molecules required for T cell activation, including CD40 and B7. The latter can interact with CD28 on the surface of a CD4+ T cell...

Cytokines (/'saɪ.tə.kaɪn/) are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling. Due to their size, cytokines cannot...

derived growth factor (translocates to nucleus) HGS LTBP4 VEGFB ZFP36L1 CD40 formerly TNFRSF5 CSNK1E CSNK2B ALAS1 Aminolevulinic Acid Synthase type 1...

Presbyterian Hospital). As assistant professor at Columbia, Lederman discovered the CD40-Ligand (CD154) and elucidated the molecular basis of T cell helper function...

C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as...

The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis...

anion transport protein, also known as anion exchanger 1 (AE1) or band 3 or solute carrier family 4 member 1 (SLC4A1), is a protein that is encoded by...

resistance protein 1 (MDR1) or ATP-binding cassette sub-family B member 1 (ABCB1) or cluster of differentiation 243 (CD243) is an important protein of the...