Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system of vertebrates– a class of cell membrane receptors in the G...

Cannabinoid receptor 1 (CB1), is a G protein-coupled cannabinoid receptor that in humans is encoded by the CNR1 gene. And discovered, by determination...

animal organisms (although insects lack such receptors) or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol...

The cannabinoid receptor 2 (CB2), is a G protein-coupled receptor from the cannabinoid receptor family that in humans is encoded by the CNR2 gene. It...

A cannabinoid receptor antagonist, also known simply as a cannabinoid antagonist or as an anticannabinoid, is a type of cannabinoidergic drug that binds...

Synthetic cannabinoids are a class of designer drug molecules that bind to the same receptors to which cannabinoids (THC, CBD and many others) in cannabis...

dose-dependent buildup of cannabinoids and related effects of cannabinoid toxicity the functionality of cannabinoid receptors in the brain and particularly...

endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the central...

users experience, little is known about CBD's effects on humans. Cannabinoid receptor antagonists have previously been tested as antidotes for cannabis...

GPR55, along with GPR119 and GPR18, have been implicated as novel cannabinoid receptors. GPR55 was identified and cloned for the first time in 1999. Later...

PMID 16968947. Hongfeng Deng. Design and synthesis of selective cannabinoid receptor ligands: Aminoalkylindole and other heterocyclic analogs. PhD Dissertation...

to that of Δ9-THC, with central effects occurring by binding to cannabinoid receptors found in various regions of the brain. Partial synthesis of ∆8-THC...

CB1 receptors, meaning that much higher doses of CBN are required in order to experience effects, such as mild sedation. It was the first cannabinoid to...

greater downregulation of cannabinoid receptors than endocannabinoids. Furthermore, in populations of low cannabinoid receptor density, THC may even act...

(also incorrectly known as 5-CL-ADB-A) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug. MDMB-4en-PINACA was first...

2015). "Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor". British Journal of Pharmacology. 172 (20): 4790–4805. doi:10...

inverse agonist for the cannabinoid receptor CB1 and was first-in-class for clinical development. Rimonabant is a selective CB1 receptor blocker and was discovered...

To exert the psychoactive effect, specific receptors such as cannabinoid, dopamine and serotonin receptors are either stimulated or inhibited There are...

total cannabinoids have been reported.[2] THCV is a cannabinoid receptor type 1 antagonist or, at higher doses, a CB1 receptor agonist and cannabinoid receptor...

Ki is the compound's binding affinity for the cannabinoid receptor type 1 (CB1) or cannabinoid receptor type 2 (CB2). Manera C, Tuccinardi T, Martinelli...

potent but nonselective full agonist for the cannabinoid receptor. It is part of the AM series of cannabinoids discovered by Alexandros Makriyannis at Northeastern...

"Delta9-tetrahydrocannabinol and endogenous cannabinoid anandamide directly potentiate the function of glycine receptors". Molecular Pharmacology. 69 (3): 991–97...

engages with the body's endocannabinoid system by binding to the same cannabinoid receptors that THC found in cannabis acts on. Anandamide can be found within...

Fernández-Ruiz, J. J. (1999-09-01). "Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain...

ECP-012A; Arvisol, Epidiolex) – cannabinoid receptor modulator, antioxidant, other actions CVN766 – Orexin receptor type 1 antagonist Deudextromethorphan...

anti-dopaminergic and a dopamine receptor antagonist (DRA), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics...

(nabiximols) Nabilone, a novel synthetic cannabinoid HU-308, a highly potent synthetic cannabinoid CB2 receptor agonist Gaoni Y, Mechoulam R (April 1964)...

at least 113 cannabinoids; however, most of these "minor" cannabinoids are only produced in trace amounts. Besides THC, another cannabinoid produced in...

Cannabidiol (CBD) is a phytocannabinoid, one of 113 identified cannabinoids in cannabis plants, along with tetrahydrocannabinol (THC), and accounts for...

peroxisome proliferator-activated receptor alpha (PPAR-α). PEA also has affinity to cannabinoid-like G-coupled receptors GPR55 and GPR119. PEA cannot strictly...