of a translocation is generally a double-strand break in chromosomal DNA. A type of DNA repair that has a major role in generating chromosomal translocations...

Robertsonian translocation (ROB) is a chromosomal abnormality where the entire long arms of two different chromosomes become fused to each other. It is...

Look up translocation in Wiktionary, the free dictionary. Translocation may refer to: Chromosomal translocation, a chromosome abnormality caused by rearrangement...

The Philadelphia chromosome or Philadelphia translocation (Ph) is a specific genetic abnormality in chromosome 22 of leukemia cancer cells (particularly...

A chromosomal abnormality, chromosomal anomaly, chromosomal aberration, chromosomal mutation, or chromosomal disorder is a missing, extra, or irregular...

advanced; nodal or extranodal) The person's general health status. Chromosomal translocations involving the immunoglobulin heavy locus is a classic cytogenetic...

to a clear genetic abnormality, the chromosomal translocation known as the Philadelphia chromosome. This chromosomal abnormality is so named because it...

syndrome. These include gene mutations in JAK2, ABL1, and FLT2 and chromosomal translocations that create the ETV6-ACSL6 fusion gene. Chronic eosinophilic leukemia...

defined endpoints." By combining chromosomal translocation, chromosomal inversion, and chromosomal deletion, chromosome engineering has been shown to identify...

constitutional chromosomal translocation t(11;22)(q23;q11), owing to a 3:1 meiotic malsegregation event resulting in partial trisomy of chromosomes 11 and 22...

granulocytes called promyelocytes. The disease is characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARA) gene and is...

little to no effect. Some chromosome abnormalities do not cause disease in carriers, such as translocations, or chromosomal inversions, although they...

is a chromosomal translocation which essentially always involves the immunoglobulin heavy locus, also known as IGH in the q32 region of chromosome 14,...

These differences probably came about through translocations. Differences in relative size of chromosomes. These differences probably arose from segmental...

result of a chromosomal translocation or chromosomal inversion. In a translocation, genetic material is transferred from one chromosome to another, either...

member of the ETS transcription factor family) of chromosome 11. The resultant chromosomal translocation causes the EWS trans-activation domain (which is...

Ewing sarcoma are associated with a chromosomal translocation in which part of chromosome 11 fuses with part of chromosome 22. This results in the EWSR1 gene...

American human geneticist and the first scientist to identify a chromosomal translocation as the cause of leukemia and other cancers, thus proving that...

type of chromosome abnormality), resulting in an increased amount of protein in the cell A chromosomal translocation (another type of chromosome abnormality)...

meiosis, the chromosomal arrangement interferes with normal separation of chromosomes. Possible gametic arrangements are (see translocation karyotype figure):...

aggressive course of MCL. Chromosomal assessment using fluorescence in situ hybridization shows the characteristic chromosomal translocation t(11;14)(q13;q32)...

of white and red sectors. These phenotypes are often due to a chromosomal translocation such that the color gene is now close to a region of heterochromatin...

people with AML; the types of chromosomal abnormalities often have prognostic significance. The chromosomal translocations encode abnormal fusion proteins...

mutant proteins occur naturally when a complex mutation, such as a chromosomal translocation, tandem duplication, or retrotransposition creates a novel coding...

(STR) Y linkage Y-chromosomal Aaron Y-chromosomal Adam Y-chromosome haplogroups in populations of the world "Homo sapiens Y chromosome genes". CCDS Release...

rearranging a chromosome in "cis", it can also occur (in 10 to 20% of cases, depending upon the Ig class) as an inter-chromosomal translocation mixing immunoglobulin...

with a translocation between chromosomes 12 and 21. Another form of leukemia, acute myeloid leukemia, has been associated with a translocation between...

significant chromosomal abnormalities. These include the addition of chromosomes, the loss of entire chromosomes, partial loss of chromosomes, and chromosomal translocation...

transport. Cancer cells often exhibit chromosomal abnormalities, including chromosomal rearrangements (such as translocations), deletions, and duplications....

as a way of measuring MRD in leukemias that do not contain a chromosomal translocation or other leukemic specific marker. In this case, the leukemic-specific...