QT prolongation is a measure of delayed ventricular repolarisation, which means the heart muscle takes longer than normal to recharge between beats. It...
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normal QTd. Electrocardiogram Long QT syndrome Short QT syndrome QT interval variability Drug-induced QT prolongation Panicker GK, Salvi V, Karnad DR, Chakraborty...
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can make people more susceptible to significant drug-induced QT prolongation. The various forms of long QT syndrome, both congenital and acquired, produce...
64 KB (6,612 words) - 23:16, 28 October 2024
drugs and/or electrolyte disorders that cause excessive lengthening of the QT interval. Common causes for torsades de pointes include drug-induced QT...
26 KB (2,978 words) - 17:33, 5 November 2024
CredibleMeds (section Adverse drug event analysis)
launched in 2009 of information regarding serious drug-drug interactions associated with QT prolongation or the potentially lethal arrhythmia, torsades de...
6 KB (719 words) - 12:19, 31 October 2023
Azithromycin (category Drugs with non-standard legal status)
associated with deleterious outcomes in COVID-19 patients, including drug-induced QT prolongation. After a large-scale trial showed no benefit of using azithromycin...
62 KB (5,600 words) - 19:30, 19 October 2024
monitoring of known cardiac arrhythmias Medication monitoring (e.g., drug-induced QT prolongation, digoxin toxicity) and management of overdose (e.g., tricyclic...
91 KB (10,038 words) - 19:29, 29 October 2024
457–468. doi:10.1016/j.cnur.2017.04.007. PMID 28779826. "Drug-Induced Prolongation of the QT Interval and Torsades de Pointes". Lexicomp. 29 April 2023...
32 KB (3,277 words) - 01:42, 12 August 2024
Antidepressant (redirect from Antidepressant drug)
depressive disorders. Tricyclics and SSRI can cause the so-called drug-induced QT prolongation, especially in older adults; this condition can degenerate into...
193 KB (20,781 words) - 15:57, 6 November 2024
Ondansetron (category Drugs with non-standard legal status)
the metabolism of other drugs broken down by this system. Use of ondansetron has been associated with prolongation of the QT interval, which can lead...
34 KB (3,159 words) - 03:47, 15 September 2024
Ranolazine (category Drugs with non-standard legal status)
headache, nausea, and dizziness. Serious side effects may include QT prolongation. Ranolazine is contraindicated (not recommended) in those with liver...
18 KB (1,525 words) - 15:43, 23 September 2024
Escitalopram (category Drugs with non-standard legal status)
dose-dependent QT interval prolongation, which is a measure of how rapidly the heart muscle repolarizes after each heartbeat. Prolongation of the QT interval...
58 KB (5,392 words) - 03:22, 2 November 2024
Domperidone (category Drugs with non-standard legal status)
irregularities, and hypogonadism can occur. Domperidone may also cause QT prolongation and has rarely been associated with serious cardiac complications such...
64 KB (5,718 words) - 20:32, 25 October 2024
1080/0886022X.2019.1707098. ISSN 0886-022X. PMC 6968512. PMID 31878817. "Drug-induced QT prolongation and Torsades de Pointes - the facts". www.medsafe.govt.nz. Retrieved...
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Lofexidine (category Drugs with non-standard legal status)
Slow heart rate Dizziness Sleepiness Dry mouth Low blood pressure QT prolongation In addition, people may experience a sudden jump in blood pressure...
15 KB (1,396 words) - 22:26, 15 October 2024
Pharmacological cardiotoxicity (redirect from Drug-induced cardiotoxicity)
2013). "Development and Validation of a Risk Score to Predict QT Interval Prolongation in Hospitalized Patients". Circulation: Cardiovascular Quality...
26 KB (3,076 words) - 01:50, 8 November 2024
Haloperidol (redirect from Halol (drug))
dyskinesia which may be permanent. Neuroleptic malignant syndrome and QT interval prolongation may occur, the latter particularly with IV administration. In older...
61 KB (5,376 words) - 08:07, 2 November 2024
Fluconazole (category Multiple chemicals in Infobox drug)
increased liver enzymes. Serious side effects may include liver problems, QT prolongation, and seizures. During pregnancy it may increase the risk of miscarriage...
31 KB (2,817 words) - 04:18, 27 October 2024
Outline of cardiology (section Drugs)
lengthening of the QT interval — drug-induced QT prolongation — and an EKG may be warranted before starting the medication to ensure a normal QT interval, but...
58 KB (7,309 words) - 05:04, 7 July 2024
Levocetirizine (category Multiple chemicals in Infobox drug)
PMID 17891537. S2CID 36218027. "Cetirizine and loratadine: minimal risk of QT prolongation". Prescrire International. 19 (105): 26–28. February 2010. PMID 20455340...
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Guanfacine (redirect from Tenex (drug))
sedation, and QT prolongation. Guanfacine availability is significantly affected by the CYP3A4 and CYP3A5 enzymes. Medications that inhibit or induce those enzymes...
43 KB (3,962 words) - 04:55, 24 October 2024
Sotalol (category Drugs with non-standard legal status)
seeing, vomiting, and swelling. Other serious side effects may include QT prolongation, heart failure, or bronchospasm. Sotalol is a non-selective β-adrenergic...
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Analgesic (redirect from Pain killing drug)
opioid-induced hyperalgesia. The symptoms of these two conditions can appear very similar but the mechanism of action is different. Opioid-induced hyperalgesia...
109 KB (5,859 words) - 00:50, 28 October 2024
Clarithromycin (category Drugs with non-standard legal status)
component of the product, erythromycin, or any macrolide antibiotics. QT prolongation or ventricular cardiac arrhythmias, including torsade de pointes. The...
29 KB (2,711 words) - 14:43, 22 October 2024
diarrhea. Famotidine may contribute to QT prolongation, particularly when used with other QT-elongating drugs, or in people with poor kidney function...
27 KB (2,349 words) - 02:38, 2 November 2024
affected by cigarette smoke, while ziprasidone may cause QT prolongation if used with other drugs that have similar cardiac effects. Britannica, T. Editors...
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Hydrocodone (category Drugs with non-standard legal status)
constipation. Serious side effects may include low blood pressure, seizures, QT prolongation, respiratory depression, and serotonin syndrome. Rapidly decreasing...
55 KB (4,903 words) - 20:06, 3 November 2024
Chloroquine (redirect from Imagon (drug))
azithromycin, has been associated with deleterious outcomes, such as QT prolongation. As of 2024,[update] scientific evidence does not substantiate the...
48 KB (5,825 words) - 03:28, 4 November 2024
HERG (section Drug interactions)
decreased channel function and drug-induced (acquired) long QT syndrome. Among the drugs that can cause QT prolongation, the more common ones include antiarrhythmics...
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Antipsychotic (redirect from Antipsychotic drug)
iron plasma levels, electrolyte abnormalities, etc.) Pancreatitis QT interval prolongation — more prominent in those treated with amisulpride, pimozide, sertindole...
211 KB (18,597 words) - 03:51, 2 November 2024