Forkhead box O3, also known as FOXO3 or FOXO3a, is a human protein encoded by the FOXO3 gene. FOXO3 belongs to the O subclass of the forkhead family of...
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Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
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Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
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conserved ageing-controlling pathway in evolution and among its targets are the FOXO3/Sirtuin transcription factors and the mTOR complexes, probably responsive...
90 KB (10,704 words) - 22:31, 4 July 2024
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
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Ovarian follicle activation (section Foxo3)
timing and level of the Foxo3 expression is very important to regulate ovarian follicle activation. AKt- PTEN-AKt and Foxo3 are all involved in the same...
33 KB (4,011 words) - 09:53, 13 June 2024
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
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acquire cancer. The University of Hawaii has found that the "longevity gene" FOXO3 that reduces the effects of aging is more commonly found in individuals...
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widely expressed), FOXN4 FOXO1 (widely expressed: muscle, liver, pancreas), FOXO3 (apoptosis, erythroid, longevity), FOXO4 (widely expressed), FOXO6 (liver...
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Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
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ENSG00000150907 Forkhead Known motif – High-throughput in vitro [276] RTAAACATGTTTAC FOXO3 ENSG00000118689 Forkhead Known motif – High-throughput in vitro [277] GTAAACAW...
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Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
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UDP-galactose The expression of GALT is controlled by the actions of the FOXO3 gene. The absence of this enzyme results in classic galactosemia in humans...
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both nutraceuticals and pharmaceuticals (together or separately) such as FOXO3-activators. Researchers are also exploring ways to mitigate side-effects...
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involved in the regulation of transcription and stem cell fate, such as FOXO3 and EZH1. Downregulation of mitochondrial cytochrome C also reflects the...
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HGNC:1928 O00409 5821 FOXN4 HGNC:21399 Q96NZ1 5822 FOXO1 HGNC:3819 Q12778 5823 FOXO3 HGNC:3821 O43524 5824 FOXO3B HGNC:3822 A0A2Z4LIS9 5825 FOXO4 HGNC:7139 P98177...
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Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
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Forkhead family transcription factors (FoxO/FH), of which FKHR/FoxO1, FKHRL1/FoxO3 and AFX/FoxO4 are directly phosphorylated by Akt. This phosphorylation induces...
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"Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53". International Journal of Oncology. 45 (4):...
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Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
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increase kinase activity during autophagy, and activate ULK1. AMBRA1 promotes FOXO3 and Nazio et al. (2021) showed when AMBRA1 is reduced, there is inhibition...
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Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
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NFAT and mTOR if conditions are suitable for proliferation, or to AKT and FOXO3 under conditions of stress. Lacritin consists of 119 amino acids after cleavage...
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shown that circRNA is associated with heart failure and heart disease. circFOXO3, Titin genes, circSLC8A1-1 and circAmotl1 play an important role in cardiac...
55 KB (6,557 words) - 15:18, 12 May 2024
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
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2000s, he began to study the genetics of longevity, including the roles of FOXO3 and the sirtuins.: 154–155 He was awarded the Royal Society of New South...
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Ageing. 2008 (approximately) It was observed that different variants of FOXO3 gene are associated with human longevity. Since then, research has been...
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modulating nuclear localization of the autophagy-related transcription factors FOXO3/FOXO3A and TFEB, suggesting that DIRAS1, along with DIRAS2, may behave as...
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signalling. Other fork head proteins have been associated with cancer, including FoxO3 and FoxM that repress the cell survival pathways Ras and PPI3K/AKT/IKK....
24 KB (2,798 words) - 01:51, 29 November 2023
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
26 KB (271 words) - 12:44, 30 March 2024