• Thumbnail for Folate
    Folate, also known as vitamin B9 and folacin, is one of the B vitamins. Manufactured folic acid, which is converted into folate by the body, is used as...
    101 KB (11,049 words) - 22:04, 5 September 2024
  • Thumbnail for Folate deficiency
    Folate deficiency, also known as vitamin B9 deficiency, is a low level of folate and derivatives in the body. This may result in megaloblastic anemia in...
    29 KB (3,169 words) - 22:31, 6 September 2024
  • Thumbnail for Anemia
    blood donation. Causes of decreased production include iron deficiency, folate deficiency, vitamin B12 deficiency, thalassemia and a number of bone marrow...
    85 KB (8,779 words) - 02:31, 1 September 2024
  • vitamin, folate (folic acid), to a molecule/drug to form a "folate conjugate". Based on the natural high affinity of folate for the folate receptor protein...
    24 KB (3,023 words) - 00:54, 12 February 2024
  • by name than by number, such as pantothenic acid (B5), biotin (B7), and folate (B9). B vitamins are present in protein-rich foods, such as fish, poultry...
    43 KB (2,802 words) - 22:36, 5 September 2024
  • Folate receptors bind folate and reduced folic acid derivatives and mediates delivery of tetrahydrofolate to the interior of cells. It is then converted...
    2 KB (210 words) - 03:35, 17 May 2022
  • Thumbnail for Neural tube defect
    which has decreased from around 5 per 10,000 (0.05% of US births) since folate fortification of grain products was started. The number of deaths in the...
    50 KB (5,814 words) - 12:37, 7 June 2024
  • Thumbnail for Folate receptor 1
    Folate receptor 1 (Folate receptor alpha, FOLR1) is a protein that in humans is encoded by the FOLR1 gene. The protein encoded by this gene is a member...
    15 KB (1,733 words) - 06:11, 25 April 2024
  • Thumbnail for Cerebral folate deficiency
    Cerebral folate deficiency is a condition in which concentrations of 5-methyltetrahydrofolate are low in the brain as measured in the cerebral spinal fluid...
    16 KB (1,337 words) - 22:14, 24 March 2024
  • Reduced Folate Carrier (RFC) Family (TC# 2.A.48) is a group of transport proteins that is part of the major facilitator superfamily. RFCs take up folate, reduced...
    5 KB (624 words) - 13:41, 22 April 2022
  • Thumbnail for Antifolate
    such as proguanil, pyrimethamine and trimethoprim selectively inhibit folate's actions in microbial organisms such as bacteria, protozoa and fungi. The...
    10 KB (751 words) - 14:17, 14 October 2023
  • Thumbnail for Sulfamethoxazole
    intermediate interferes with the normal bacterial synthesis of folic acid (folate). Folate is an essential metabolite for bacterial growth and replication because...
    12 KB (982 words) - 05:17, 2 September 2024
  • Thumbnail for Vitamin B12 deficiency
    spinal cord strongly suggests the presence of a B12 deficiency instead of folate deficiency. Methylmalonic acid, if not properly handled by B12, remains...
    119 KB (13,167 words) - 22:31, 6 September 2024
  • Thumbnail for Spina bifida
    4% chance that the next child will also be affected. Not having enough folate (vitamin B9) in the diet before and during pregnancy also plays a significant...
    82 KB (9,149 words) - 06:01, 29 July 2024
  • Thumbnail for Hereditary folate malabsorption
    Hereditary folate malabsorption (HFM) is a rare autosomal recessive disorder caused by loss-of-function mutations in the proton-coupled folate transporter...
    25 KB (2,752 words) - 12:06, 9 August 2024
  • Thumbnail for Levomefolic acid
    Levomefolic acid (category Folates)
    (6S)-5-methyltetrahydrofolate, and (6S)-5-MTHF) is the primary biologically active form of folate used at the cellular level for DNA reproduction, the cysteine cycle and...
    15 KB (1,173 words) - 11:42, 25 June 2024
  • Thumbnail for Megaloblastic anemia
    most often due to hypovitaminosis, specifically vitamin B12 deficiency or folate deficiency. Loss of micronutrients may also be a cause. Megaloblastic anemia...
    13 KB (1,255 words) - 19:34, 7 August 2024
  • Thumbnail for Spinach
    concentration, as vitamin C is degraded by heating. Folate levels may also be decreased, as folate tends to leach into cooking liquid. Spinach is rich...
    18 KB (1,972 words) - 13:46, 4 September 2024
  • Thumbnail for Prostate cancer
    Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder. Abnormal growth of prostate...
    76 KB (8,857 words) - 09:52, 1 September 2024
  • Thumbnail for Folate transporter 1
    Folate transporter 1 is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated...
    12 KB (1,472 words) - 20:18, 27 November 2023
  • Folate-binding protein (FBP) are proteins that bind folate, typically the folate receptors and reduced folate carrier. FBP can be a marker for ovarian...
    2 KB (223 words) - 07:56, 16 April 2022
  • Thumbnail for Dark skin
    skin pigmentation was the breakdown of folate in reaction to ultraviolet radiation; the relationship between folate breakdown induced by ultraviolet radiation...
    74 KB (8,439 words) - 03:42, 3 September 2024
  • Thumbnail for Anisocytosis
    – Iron deficiency, sickle cell anemia Anisocytosis with macrocytosis – Folate or vitamin B12 deficiency, autoimmune hemolytic anemia, cytotoxic chemotherapy...
    3 KB (264 words) - 04:15, 19 November 2022
  • Thumbnail for Proton-coupled folate transporter
    The proton-coupled folate transporter is a protein that in humans is encoded by the SLC46A1 gene. The major physiological roles of PCFTs are in mediating...
    22 KB (2,649 words) - 18:32, 9 June 2024
  • Thumbnail for Hyperhomocysteinemia
    5-methyltetrahydrofolate (5-MTHF) form of folate from being converted into THF due to the "methyl trap". This disrupts the folate pathway and leads to an increase...
    20 KB (2,071 words) - 15:21, 11 April 2024
  • Thumbnail for Red blood cell distribution width
    causes from an anemia of a single cause. Deficiencies of Vitamin B12 or folate produce a macrocytic anemia (large cell anemia) in which the RDW is elevated...
    7 KB (772 words) - 01:36, 13 November 2023
  • Thumbnail for Neurulation
    1186/s12976-016-0037-2 Björklund, NK, Gordon, R A hypothesis linking low folate intake to neural tube defects due to failure of post-translation methylations...
    26 KB (3,288 words) - 08:13, 12 July 2024
  • naturally-occurring forms of folate, and which only contributes a minor amount to the folates occurring in natural foods. In many cases, such as with folate, it is an open...
    30 KB (3,406 words) - 17:22, 27 August 2024
  • Thumbnail for Yogurt
    (B3) 1% 0.208 mg Pantothenic acid (B5) 7% 0.331 mg Vitamin B6 4% 0.063 mg Folate (B9) 1% 5 μg Vitamin B12 31% 0.75 μg Choline 3% 15.1 mg Vitamin C 0% 0 mg...
    53 KB (5,704 words) - 17:47, 2 September 2024
  • Thumbnail for Formiminoglutamic acid
    folate. The FIGLU test is used to identify vitamin B₁₂ deficiency, folate deficiency, and liver failure or liver disease. It is elevated with folate trapping...
    2 KB (197 words) - 13:00, 18 September 2023