Folate, also known as vitamin B9 and folacin, is one of the B vitamins. Manufactured folic acid, which is converted into folate by the body, is used as...
101 KB (11,049 words) - 22:04, 5 September 2024
Folate deficiency, also known as vitamin B9 deficiency, is a low level of folate and derivatives in the body. This may result in megaloblastic anemia in...
29 KB (3,169 words) - 22:31, 6 September 2024
Anemia (redirect from Dietary folate deficiency anaemia)
blood donation. Causes of decreased production include iron deficiency, folate deficiency, vitamin B12 deficiency, thalassemia and a number of bone marrow...
85 KB (8,779 words) - 02:31, 1 September 2024
vitamin, folate (folic acid), to a molecule/drug to form a "folate conjugate". Based on the natural high affinity of folate for the folate receptor protein...
24 KB (3,023 words) - 00:54, 12 February 2024
by name than by number, such as pantothenic acid (B5), biotin (B7), and folate (B9). B vitamins are present in protein-rich foods, such as fish, poultry...
43 KB (2,802 words) - 22:36, 5 September 2024
Folate receptors bind folate and reduced folic acid derivatives and mediates delivery of tetrahydrofolate to the interior of cells. It is then converted...
2 KB (210 words) - 03:35, 17 May 2022
Neural tube defect (section Folate deficiency)
which has decreased from around 5 per 10,000 (0.05% of US births) since folate fortification of grain products was started. The number of deaths in the...
50 KB (5,814 words) - 12:37, 7 June 2024
Folate receptor 1 (Folate receptor alpha, FOLR1) is a protein that in humans is encoded by the FOLR1 gene. The protein encoded by this gene is a member...
15 KB (1,733 words) - 06:11, 25 April 2024
Cerebral folate deficiency is a condition in which concentrations of 5-methyltetrahydrofolate are low in the brain as measured in the cerebral spinal fluid...
16 KB (1,337 words) - 22:14, 24 March 2024
Reduced Folate Carrier (RFC) Family (TC# 2.A.48) is a group of transport proteins that is part of the major facilitator superfamily. RFCs take up folate, reduced...
5 KB (624 words) - 13:41, 22 April 2022
Antifolate (redirect from Folate antagonists)
such as proguanil, pyrimethamine and trimethoprim selectively inhibit folate's actions in microbial organisms such as bacteria, protozoa and fungi. The...
10 KB (751 words) - 14:17, 14 October 2023
intermediate interferes with the normal bacterial synthesis of folic acid (folate). Folate is an essential metabolite for bacterial growth and replication because...
12 KB (982 words) - 05:17, 2 September 2024
spinal cord strongly suggests the presence of a B12 deficiency instead of folate deficiency. Methylmalonic acid, if not properly handled by B12, remains...
119 KB (13,167 words) - 22:31, 6 September 2024
4% chance that the next child will also be affected. Not having enough folate (vitamin B9) in the diet before and during pregnancy also plays a significant...
82 KB (9,149 words) - 06:01, 29 July 2024
Hereditary folate malabsorption (HFM) is a rare autosomal recessive disorder caused by loss-of-function mutations in the proton-coupled folate transporter...
25 KB (2,752 words) - 12:06, 9 August 2024
Levomefolic acid (category Folates)
(6S)-5-methyltetrahydrofolate, and (6S)-5-MTHF) is the primary biologically active form of folate used at the cellular level for DNA reproduction, the cysteine cycle and...
15 KB (1,173 words) - 11:42, 25 June 2024
most often due to hypovitaminosis, specifically vitamin B12 deficiency or folate deficiency. Loss of micronutrients may also be a cause. Megaloblastic anemia...
13 KB (1,255 words) - 19:34, 7 August 2024
concentration, as vitamin C is degraded by heating. Folate levels may also be decreased, as folate tends to leach into cooking liquid. Spinach is rich...
18 KB (1,972 words) - 13:46, 4 September 2024
Prostate cancer (redirect from Prostate cancer folate supplementation)
Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder. Abnormal growth of prostate...
76 KB (8,857 words) - 09:52, 1 September 2024
Folate transporter 1 is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated...
12 KB (1,472 words) - 20:18, 27 November 2023
Folate-binding protein (FBP) are proteins that bind folate, typically the folate receptors and reduced folate carrier. FBP can be a marker for ovarian...
2 KB (223 words) - 07:56, 16 April 2022
skin pigmentation was the breakdown of folate in reaction to ultraviolet radiation; the relationship between folate breakdown induced by ultraviolet radiation...
74 KB (8,439 words) - 03:42, 3 September 2024
– Iron deficiency, sickle cell anemia Anisocytosis with macrocytosis – Folate or vitamin B12 deficiency, autoimmune hemolytic anemia, cytotoxic chemotherapy...
3 KB (264 words) - 04:15, 19 November 2022
The proton-coupled folate transporter is a protein that in humans is encoded by the SLC46A1 gene. The major physiological roles of PCFTs are in mediating...
22 KB (2,649 words) - 18:32, 9 June 2024
5-methyltetrahydrofolate (5-MTHF) form of folate from being converted into THF due to the "methyl trap". This disrupts the folate pathway and leads to an increase...
20 KB (2,071 words) - 15:21, 11 April 2024
causes from an anemia of a single cause. Deficiencies of Vitamin B12 or folate produce a macrocytic anemia (large cell anemia) in which the RDW is elevated...
7 KB (772 words) - 01:36, 13 November 2023
Neurulation (redirect from Neural tube defect, folate-sensitive)
1186/s12976-016-0037-2 Björklund, NK, Gordon, R A hypothesis linking low folate intake to neural tube defects due to failure of post-translation methylations...
26 KB (3,288 words) - 08:13, 12 July 2024
Food fortification (section Folate)
naturally-occurring forms of folate, and which only contributes a minor amount to the folates occurring in natural foods. In many cases, such as with folate, it is an open...
30 KB (3,406 words) - 17:22, 27 August 2024
(B3) 1% 0.208 mg Pantothenic acid (B5) 7% 0.331 mg Vitamin B6 4% 0.063 mg Folate (B9) 1% 5 μg Vitamin B12 31% 0.75 μg Choline 3% 15.1 mg Vitamin C 0% 0 mg...
53 KB (5,704 words) - 17:47, 2 September 2024
folate. The FIGLU test is used to identify vitamin B₁₂ deficiency, folate deficiency, and liver failure or liver disease. It is elevated with folate trapping...
2 KB (197 words) - 13:00, 18 September 2023