A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other...
8 KB (740 words) - 14:44, 20 August 2024
The carboxylate form of GABA is γ-aminobutyrate. Two general classes of GABA receptor are known: GABAA in which the receptor is part of a ligand-gated...
51 KB (5,494 words) - 04:45, 10 August 2024
acid) – synthetic GHB receptor agonist GABOB (β-hydroxy-GABA) – anticonvulsant; GABA receptor agonist Pregabalin (β-isobutyl-GABA) – analgesic, anticonvulsant...
8 KB (754 words) - 04:40, 27 January 2024
The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel. Its endogenous ligand is γ-aminobutyric acid (GABA), the major inhibitory...
54 KB (5,844 words) - 13:37, 26 July 2024
The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature...
35 KB (3,892 words) - 05:20, 16 May 2024
A dopamine agonist is a compound that activates dopamine receptors. There are two families of dopamine receptors, D1-like and D2-like. They are all G...
44 KB (5,009 words) - 01:01, 9 August 2024
not present. Unlike GABAA receptor agonists, GABAA PAMs do not bind at the same active site as the γ-aminobutyric acid (GABA) neurotransmitter molecule:...
31 KB (3,522 words) - 00:57, 6 June 2024
Alpha-adrenergic agonists are a class of sympathomimetic agents that selectively stimulates alpha adrenergic receptors. The alpha-adrenergic receptor has two subclasses...
14 KB (1,365 words) - 17:04, 1 September 2024
A serotonin receptor agonist is an agonist of one or more serotonin receptors. They activate serotonin receptors in a manner similar to that of serotonin...
16 KB (1,657 words) - 17:23, 8 June 2024
agonists of the beta receptors are selective for one or more beta-adrenoreceptors. For example, patients with low heart rate are given beta agonist treatments...
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Muscimol (category GABAA receptor agonists)
GABA-A receptor agonist, meaning it mimics the action of GABA, the main inhibitory neurotransmitter in the central nervous system. By binding to GABA-A...
37 KB (3,826 words) - 05:00, 11 August 2024
GABAB receptors (GABABR) are G-protein coupled receptors for gamma-aminobutyric acid (GABA), therefore making them metabotropic receptors, that are linked...
16 KB (1,564 words) - 20:19, 25 March 2024
4-Fluorophenibut (redirect from Β-(4-fluorophenyl)-GABA)
β-(4-fluorophenyl)-GABA) is a GABAB receptor agonist which was never marketed. It is selective for the GABAB receptor over the GABAA receptor (IC50 = 1.70 μM...
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receptor rather than activating it like an agonist. Antagonist drugs interfere in the natural operation of receptor proteins. They are sometimes called blockers;...
33 KB (3,845 words) - 01:47, 19 August 2024
An adrenergic agonist is a drug that stimulates a response from the adrenergic receptors. The five main categories of adrenergic receptors are: α1, α2,...
7 KB (750 words) - 04:55, 1 April 2024
Gamma-Hydroxybutyric acid (category GABAB receptor agonists)
precursor to GABA, glutamate, and glycine in certain brain areas. It acts on the GHB receptor and is a weak agonist at the GABAB receptor. GHB has been...
89 KB (9,445 words) - 11:12, 26 August 2024
Beta2-adrenergic agonists, also known as adrenergic β2 receptor agonists, are a class of drugs that act on the β2 adrenergic receptor. Like other β adrenergic...
18 KB (1,703 words) - 06:18, 17 March 2024
Parasympathomimetic drug (redirect from Acetylcholine receptor agonist)
Clonidine (α-receptor agonist, α2 > α1, giving negative feedback) Methyldopa (α2 agonist, giving negative feedback) Propranolol (β-receptor antagonist)...
7 KB (618 words) - 06:38, 29 April 2024
Phenibut (redirect from Phenyl-GABA)
neurotransmitter γ-aminobutyric acid (GABA), and hence is a GABA analogue. Phenibut is thought to act as a GABAB receptor agonist, similarly to baclofen and γ-hydroxybutyrate...
36 KB (2,858 words) - 14:31, 24 August 2024
Cannabinoid (redirect from Cannabinoid receptor agonist)
CB2 receptors but acts as an indirect antagonist of cannabinoid agonists. It was found to be an antagonist at the putative new cannabinoid receptor, GPR55...
73 KB (7,813 words) - 11:31, 14 August 2024
Gamma-Amino-beta-hydroxybutyric acid (redirect from Β-hydroxy-GABA)
anticonvulsant and is used in the treatment of epilepsy. GABOB is a GABA receptor agonist. It has two stereoisomers, and shows stereoselectivity in its actions...
8 KB (688 words) - 09:14, 5 December 2023
Cholinergic (redirect from Cholinergic agonist)
behaviours at one or more of the body's acetylcholine receptor ("direct-acting") or butyrylcholine receptor types ("direct-acting"). Such mimics are called...
9 KB (965 words) - 13:45, 21 December 2023
GABA receptor antagonists are drugs that inhibit the action of GABA. In general these drugs produce stimulant and convulsant effects, and are mainly used...
3 KB (315 words) - 21:55, 14 April 2024
A muscarinic agonist is an agent that activates the activity of the muscarinic acetylcholine receptor. The muscarinic receptor has different subtypes...
7 KB (642 words) - 03:58, 16 December 2023
Antihistamine (redirect from H1 receptor antagonist)
H1 receptor. Since the H1 receptor exhibits constitutive activity, H1-antihistamines can be either neutral receptor antagonists or inverse agonists. Normally...
32 KB (3,140 words) - 11:09, 17 August 2024
Dopamine antagonist (redirect from Dopamine receptor antagonist)
anti-dopaminergic and a dopamine receptor antagonist (DRA), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics...
25 KB (2,401 words) - 02:56, 4 June 2024
these modulators include receptor agonists and receptor antagonists, as well as receptor partial agonists, inverse agonists, orthosteric modulators, and...
8 KB (982 words) - 02:36, 19 May 2024
Ligand-gated ion channel (redirect from Ionotropic receptor)
analog AMPA. The receptor was first named the "quisqualate receptor" by Watkins and colleagues after a naturally occurring agonist quisqualate and was...
29 KB (2,597 words) - 03:43, 7 April 2024
Dopaminergic (section Dopamine receptor agonists)
depression and anxiety. Dopamine receptor agonists can be divided into D1-like receptor agonists and D2-like receptor agonists. Positive allosteric modulators...
17 KB (1,661 words) - 23:20, 25 August 2024
Neurotransmitter (redirect from Receptors, neurotransmitter)
receptor, cannabinoid receptor 1 (CB1), is presynaptic. The cannabis plant contains Δ9-tetrahydrocannabinol, which is a direct agonist at CB1. GABA is...
94 KB (8,341 words) - 08:44, 9 August 2024