Glycosaminoglycans (GAGs) or mucopolysaccharides are long, linear polysaccharides consisting of repeating disaccharide units (i.e. two-sugar units). The...

Polysulfated glycosaminoglycan (PSGAG), sold under the brand name Adequan, is an injectable drug for dogs and horses that is used to alleviate the limpness...

enzymology, a glycosaminoglycan galactosyltransferase (EC 2.4.1.74) is an enzyme that catalyzes the chemical reaction UDP-galactose + glycosaminoglycan ⇌ {\displaystyle...

covalently attached glycosaminoglycan (GAG) chain(s). The point of attachment is a serine (Ser) residue to which the glycosaminoglycan is joined through...

glycosaminoglycan found in various connective tissue of humans. Sodium hyaluronate is the sodium salt of hyaluronic acid. It is a glycosaminoglycan and...

Sulodexide, traded as Aterina, is a highly purified mixture of glycosaminoglycans composed of heparan sulfate (80%) and dermatan sulfate (20%). The low...

laronidase), sold as Aldurazyme, is an enzyme with the systematic name glycosaminoglycan α-L-iduronohydrolase. It catalyses the hydrolysis of unsulfated α-L-iduronosidic...

nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans as it is non-sulfated...

unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. Heparin is a blood anticoagulant that increases the activity of antithrombin...

with how the body breaks down certain large sugar molecules called glycosaminoglycans (also known as GAGs or mucopolysaccharides). In children with this...

Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid). It is...

antioxidant and anti-inflammatory effects, stimulation of collagen and glycosaminoglycan synthesis in skin fibroblasts and promotion of blood vessels growth...

increased amount of protein and mucopolysaccharides. These can include glycosaminoglycans, such as hyaluronic acid, chondroitin sulfate and other mucopolysaccharides...

kDa to which three long chains (each approximately 70-100 kDa) of glycosaminoglycans (often heparan sulfate, HS, but can be chondroitin sulfate, CS) are...

are the main HS-bearing species. Heparan sulfate is a member of the glycosaminoglycan (GAG) family of carbohydrates and is very closely related in structure...

Gene ontology Molecular function glycosaminoglycan binding calcium ion binding Cellular component extracellular region basement membrane cell junction...

Enzymes in the Golgi append proteins to glycosaminoglycans, thus creating proteoglycans. Glycosaminoglycans are long unbranched polysaccharide molecules...

tension on the tissue. It has a low content of glycosaminoglycans (2% of dry weight). Glycosaminoglycans are long, unbranched polysaccharides (relatively...

related to the concentration of proteoglycan aggregates and charged glycosaminoglycan side chains in articular cartilage. In the complex of Gd3+ and DTPA5−...

by binding to hyaluronan. Attached to each aggrecan molecule are glycosaminoglycan (GAG) chains of chondroitin sulfate and keratan sulfate. Increasing...

Dermatan sulfate is a glycosaminoglycan (formerly called a mucopolysaccharide) found mostly in skin, but also in blood vessels, heart valves, tendons...

(a type of collagen), a network of collagen type II fibrils with glycosaminoglycan, hyaluronan, opticin, and a wide array of proteins. Despite having...

proteoglycans share a homologous globular N-terminal, C-terminal, and glycosaminoglycan (GAG) binding regions. The N-terminal (G1) globular domain consists...

bundles in the fibrosa. This is due to an excess of dermatan sulfate, a glycosaminoglycan. This weakens the leaflets and adjacent tissue, resulting in increased...

a deficiency of normal components of tracheal ring cartilage like glycosaminoglycans, glycoproteins, calcium, and chondroitin. Acquired tracheal collapse...

clinical anticoagulant worldwide. Heparin is a naturally occurring glycosaminoglycan. There are three major categories of heparin: unfractionated heparin...

the penis. Urethral glands produce a colloid secretion containing glycosaminoglycans; this secretion protects the epithelium against urine. Untreated urethritis...

patched binding peptidase activity zinc ion binding laminin-1 binding glycosaminoglycan binding morphogen activity hydrolase activity protein binding endopeptidase...

cells. This layer contains heparan sulfate, a negatively charged glycosaminoglycan that contributes to the electrostatic barrier of the glomerular filter...

epithelial matrix changes. The absence of proteoglycans, which are glycosaminoglycan chains attached to protein, may contribute to PLE and augment inflammatory...