Helicases are a class of enzymes thought to be vital to all organisms. Their main function is to unpack an organism's genetic material. Helicases are...
56 KB (6,916 words) - 19:33, 23 July 2024
RecQ helicase is a family of helicase enzymes initially found in Escherichia coli that has been shown to be important in genome maintenance. They function...
17 KB (1,883 words) - 02:48, 12 July 2024
helicase, also known as DNA helicase, RecQ-like type 3, is an enzyme that in humans is encoded by the WRN gene. WRN is a member of the RecQ Helicase family...
29 KB (3,671 words) - 05:59, 11 June 2024
DnaB helicase is an enzyme in bacteria which opens the replication fork during DNA replication. Although the mechanism by which DnaB both couples ATP hydrolysis...
6 KB (766 words) - 18:59, 14 June 2024
A helicase–primase complex (also helicase-primase, Hel/Prim, H-P or H/P) is a complex of enzymes including DNA helicase and DNA primase. A helicase-primase...
3 KB (331 words) - 02:16, 27 January 2024
PIF1 5'-to-3' DNA helicase is a protein that in humans is encoded by the PIF1 gene. This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing...
4 KB (541 words) - 02:04, 4 March 2023
ATP-dependent RNA helicase A (RHA; also known as DHX9, LKP, and NDHI) is an enzyme that in humans is encoded by the DHX9 gene. DEAD/DEAH box helicases are proteins...
14 KB (1,658 words) - 12:14, 13 May 2024
Helicase-dependent amplification (HDA) is a method for in vitro DNA amplification (like the polymerase chain reaction) that takes place at a constant temperature...
5 KB (741 words) - 17:10, 7 November 2022
DNA helicases for leading strands and lagging strands are loaded on the template DNAs, the helicases run along the DNAs into each other. The helicases remain...
60 KB (7,286 words) - 08:26, 2 July 2024
DEAD box (redirect from DEAD/DEAH box helicase)
but not all. Many organisms, including humans, contain DEAD-box (SF2) helicases, which are involved in RNA metabolism. DEAD box proteins were first brought...
12 KB (1,436 words) - 16:39, 3 April 2024
strand. To synthesize DNA, the double-stranded DNA is unwound by DNA helicases ahead of polymerases, forming a replication fork containing two single-stranded...
119 KB (14,646 words) - 22:02, 3 July 2024
Helicase, POLQ-like, also known as Helicase Q (HELQ), HEL308 and Holliday junction migration protein, encoded by the gene HELQ1, is a DNA helicase found...
14 KB (1,600 words) - 05:16, 15 July 2024
Minichromosome maintenance (redirect from MCM helicase)
The minichromosome maintenance protein complex (MCM) is a DNA helicase essential for genomic DNA replication. Eukaryotic MCM consists of six gene products...
24 KB (3,042 words) - 22:16, 29 October 2022
LGP2 (redirect from Probable ATP-dependent RNA helicase DHX58)
ATP-dependent RNA helicase DHX58 also known as RIG-I-like receptor 3 (RLR-3) or RIG-I-like receptor LGP2 (RLR) is a RIG-I-like receptor dsRNA helicase enzyme that...
9 KB (1,101 words) - 12:27, 13 August 2023
RNA helicase database stored data about RNA helicases. The URL referenced in the article has been invalid since at least December 31st 2017. Helicase Jankowsky...
1 KB (71 words) - 15:06, 2 May 2024
DHX8 (redirect from DEAH-box helicase 8)
DEAH-box helicase 8, is a protein that in humans is encoded by the DHX8 gene. This protein is member of the DEAH box polypeptide family. The main characteristic...
11 KB (1,311 words) - 19:13, 24 July 2024
Dicer (redirect from Helicase with RNase motif)
Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene. Being part of the...
25 KB (3,219 words) - 05:09, 24 July 2024
T7 DNA helicase (gp4) is a hexameric motor protein encoded by T7 phages that uses energy from dTTP hydrolysis to process unidirectionally along single...
5 KB (538 words) - 18:30, 12 June 2024
bacteria, primase binds to the DNA helicase forming a complex called the primosome. Primase is activated by the helicase where it then synthesizes a short...
20 KB (2,371 words) - 16:05, 10 July 2024
Chromodomain helicase DNA-binding (CHD) proteins is a subfamily of ATP-dependent chromatin remodeling complexes (remodelers). All remodelers fall under...
6 KB (756 words) - 11:06, 22 February 2024
Twinkle protein also known as twinkle mtDNA helicase is a mitochondrial protein that in humans is encoded by the TWNK gene (also known as C10orf2 or PEO1)...
15 KB (1,860 words) - 21:54, 1 February 2024
the drugs act through inhibition of the viral helicase primase complex, encoded by the UL5 (helicase), UL8 (scaffold protein) and UL52 (primase) genes...
10 KB (1,000 words) - 19:04, 17 June 2024
Probable ATP-dependent RNA helicase DDX5 also known as DEAD box protein 5 or RNA helicase p68 is an enzyme that in humans is encoded by the DDX5 gene....
11 KB (1,305 words) - 05:36, 28 March 2024
The ssNA-helicase RNA motif is a conserved RNA structure that was discovered by bioinformatics. Although the ssNA-helicase motif was published as an RNA...
2 KB (267 words) - 02:44, 5 April 2022
DDX20 (redirect from DEAD-box helicase 20)
Probable ATP-dependent RNA helicase DDX20, also known as DEAD-box helicase 20 and gem-associated protein 3 (GEMIN3), is an enzyme that in humans is encoded...
14 KB (1,639 words) - 02:34, 16 July 2024
(melanoma differentiation-associated protein 5) is a RIG-I-like receptor dsRNA helicase enzyme that is encoded by the IFIH1 gene in humans. MDA5 is part of the...
18 KB (2,222 words) - 09:48, 7 July 2024
step, 5'→3' resection is continued by the Sgs1 helicase and the Exo1 and Dna2 nucleases. As a helicase, Sgs1 "unzips" the double-strand DNA, while the...
106 KB (12,105 words) - 20:29, 9 March 2024
contains an Snf2 helicase domain that is responsible for the hydrolysis of ATP to adenosine diphosphate (ADP). CHD8 encodes a DNA helicase that functions...
244 KB (26,106 words) - 16:31, 24 July 2024
a DNA helicase with ATPase activity and a H+ motor, were able to bind, and the rotation of the motor drove the ATPase activity of the helicase in reverse...
33 KB (3,752 words) - 15:11, 10 June 2024