A hexokinase is an enzyme that irreversibly phosphorylates hexoses (six-carbon sugars), forming hexose phosphate. In most organisms, glucose is the most...
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Hexokinase deficiency is an extremely rare autosomal recessive condition that falls under the category of erythroenzymopathies, or defects in red cell...
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Glycolysis (section Hexokinase and glucokinase)
impervious to G6P, hexokinase essentially acts to transport glucose into the cells from which it can then no longer escape. Hexokinase is inhibited by high...
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membrane is negatively charged. This reaction occurs due to the enzyme hexokinase, an enzyme that helps phosphorylate many six-membered ring structures...
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Enzyme activator (section Hexokinase-I)
increases the rate of glycolysis in response to the hormone glucagon. Hexokinase-I (HK-I) is an enzyme activator because it draws glucose into the glycolysis...
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Hexokinase 2 also known as HK2 is an enzyme which in humans is encoded by the HK2 gene on chromosome 2. Hexokinases phosphorylate glucose to produce glucose-6-phosphate...
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Hexokinase-1 (HK1) is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. Hexokinases phosphorylate glucose to produce glucose-6-phosphate...
26 KB (3,048 words) - 06:51, 29 April 2024
Hexokinase 3 also known as HK3 is an enzyme which in humans is encoded by the HK3 gene on chromosome 5. Hexokinases phosphorylate glucose to produce glucose-6-phosphate...
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hypoglycemia. Glucokinase (GK) is a hexokinase isozyme, related homologously to at least three other hexokinases. All of the hexokinases can mediate phosphorylation...
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reaction. For example, figure 1 shows the coupled assay for the enzyme hexokinase, which can be assayed by coupling its production of glucose-6-phosphate...
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of error. The two most common employed enzymes are glucose oxidase and hexokinase. Average blood glucose concentrations can also be measured. This method...
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The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells)...
15 KB (1,696 words) - 00:07, 20 December 2023
enzymes which specialize in glucose uptake in cells such as GLUT4 and hexokinase II are thought to be mediated in part by AMPK when it is activated. Additionally...
65 KB (7,147 words) - 05:41, 24 June 2024
isoenzymes of hexokinase are half-saturated by glucose at concentrations ranging from about 0.02 mM for hexokinase A (brain hexokinase) to about 50 mM...
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the transferase hexokinase catalyzes the phosphorylation of glucose to make glucose-6-phosphate. Active site residues of hexokinase allow for stabilization...
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Tumor hypoxia (section Hexokinase 2 expression)
for glycolysis to proceed, the hexokinase reaction activates glucose for subsequent steps. In hypoxic tumors, hexokinase mRNA abundance is significantly...
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The enzyme hexokinase is shown as a conventional ball-and-stick molecular model. To scale in the top right-hand corner are two of its substrates, ATP and...
101 KB (11,357 words) - 21:37, 30 July 2024
GLUT proteins. In the other cell types, phosphorylation occurs through a hexokinase, whereupon glucose can no longer diffuse out of the cell. The glucose...
121 KB (12,794 words) - 10:50, 6 August 2024
Hexokinase domain containing 1 (HKDC1) is an enzyme which in humans is encoded by the HKDC1 gene on chromosome 10. It is a recently discovered hexokinase...
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phosphorylation of glucose on the sixth carbon. This is catalyzed by the enzyme hexokinase in most cells, and, in higher animals, glucokinase in certain cells, most...
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enzyme is fully specified by four numerical designations. For example, hexokinase (EC 2.7.1.1) is a transferase (EC 2) that adds a phosphate group (EC 2...
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analog that is taken up by glucose-using cells and phosphorylated by hexokinase (whose mitochondrial form is significantly elevated in rapidly growing...
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produces additional equivalents of ATP.[citation needed] In glycolysis, hexokinase is directly inhibited by its product, glucose-6-phosphate, and pyruvate...
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Aerobic Glycolysis of Rat Hepatoma Cells in Culture: Role of Mitochondrial Hexokinase". Proceedings of the National Academy of Sciences. 74 (9): 3735–3739....
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The glucose is subsequently phosphorylated to glucose-6-phosphate by hexokinase. Glycogen phosphorylase with Pyridoxal phosphate as prosthetic group Alpha-1...
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non-competitive inhibition is given by glucose-6-phosphate inhibiting hexokinase in the brain. Carbons 2 and 4 on glucose-6-phosphate contain hydroxyl...
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(G-6-P) by glucokinase (hexokinase IV) which is not inhibited by G-6-P in the way that the hexokinases in other tissues (hexokinase I – III) are affected...
121 KB (13,799 words) - 18:32, 22 August 2024
polysaccharides and glycoproteins yields mannose, which is phosphorylated by hexokinase to generate mannose-6-phosphate. Mannose-6-phosphate is converted to...
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brain. [18F]FDG is taken up by cells, and subsequently phosphorylated by hexokinase (whose mitochondrial form is greatly elevated in rapidly growing malignant...
22 KB (2,363 words) - 19:12, 26 June 2024
0.7355 kW) Hefnerkerze, an old photometric unit of luminous intensity Hexokinase, an enzyme Sobolev space Hk, in mathematics .hk, Hong Kong's country top-level...
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