• Thumbnail for Hexokinase
    A hexokinase is an enzyme that irreversibly phosphorylates hexoses (six-carbon sugars), forming hexose phosphate. In most organisms, glucose is the most...
    15 KB (1,568 words) - 19:28, 22 June 2024
  • Thumbnail for Hexokinase deficiency
    Hexokinase deficiency is an extremely rare autosomal recessive condition that falls under the category of erythroenzymopathies, or defects in red cell...
    10 KB (795 words) - 05:54, 6 March 2024
  • Thumbnail for Glycolysis
    impervious to G6P, hexokinase essentially acts to transport glucose into the cells from which it can then no longer escape. Hexokinase is inhibited by high...
    82 KB (8,803 words) - 13:51, 20 August 2024
  • Thumbnail for Phosphorylation
    membrane is negatively charged. This reaction occurs due to the enzyme hexokinase, an enzyme that helps phosphorylate many six-membered ring structures...
    15 KB (1,645 words) - 19:21, 22 June 2024
  • increases the rate of glycolysis in response to the hormone glucagon. Hexokinase-I (HK-I) is an enzyme activator because it draws glucose into the glycolysis...
    4 KB (574 words) - 11:29, 13 August 2024
  • Thumbnail for HK2
    Hexokinase 2 also known as HK2 is an enzyme which in humans is encoded by the HK2 gene on chromosome 2. Hexokinases phosphorylate glucose to produce glucose-6-phosphate...
    20 KB (2,507 words) - 05:09, 17 June 2024
  • Thumbnail for HK1
    Hexokinase-1 (HK1) is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. Hexokinases phosphorylate glucose to produce glucose-6-phosphate...
    26 KB (3,048 words) - 06:51, 29 April 2024
  • Thumbnail for HK3
    Hexokinase 3 also known as HK3 is an enzyme which in humans is encoded by the HK3 gene on chromosome 5. Hexokinases phosphorylate glucose to produce glucose-6-phosphate...
    15 KB (1,868 words) - 15:32, 1 April 2024
  • Thumbnail for Glucokinase
    hypoglycemia. Glucokinase (GK) is a hexokinase isozyme, related homologously to at least three other hexokinases. All of the hexokinases can mediate phosphorylation...
    44 KB (5,655 words) - 08:25, 20 August 2024
  • Thumbnail for Enzyme assay
    reaction. For example, figure 1 shows the coupled assay for the enzyme hexokinase, which can be assayed by coupling its production of glucose-6-phosphate...
    22 KB (2,934 words) - 12:43, 28 July 2024
  • Thumbnail for Blood sugar level
    of error. The two most common employed enzymes are glucose oxidase and hexokinase. Average blood glucose concentrations can also be measured. This method...
    39 KB (4,035 words) - 04:14, 25 August 2024
  • The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells)...
    15 KB (1,696 words) - 00:07, 20 December 2023
  • Thumbnail for AMP-activated protein kinase
    enzymes which specialize in glucose uptake in cells such as GLUT4 and hexokinase II are thought to be mediated in part by AMPK when it is activated. Additionally...
    65 KB (7,147 words) - 05:41, 24 June 2024
  • Thumbnail for Michaelis–Menten kinetics
    isoenzymes of hexokinase are half-saturated by glucose at concentrations ranging from about 0.02 mM for hexokinase A (brain hexokinase) to about 50 mM...
    47 KB (6,210 words) - 21:16, 22 August 2024
  • Thumbnail for Binding site
    the transferase hexokinase catalyzes the phosphorylation of glucose to make glucose-6-phosphate. Active site residues of hexokinase allow for stabilization...
    27 KB (3,035 words) - 20:48, 22 July 2024
  • Thumbnail for Tumor hypoxia
    for glycolysis to proceed, the hexokinase reaction activates glucose for subsequent steps. In hypoxic tumors, hexokinase mRNA abundance is significantly...
    52 KB (5,517 words) - 00:16, 7 June 2024
  • Thumbnail for Protein
    The enzyme hexokinase is shown as a conventional ball-and-stick molecular model. To scale in the top right-hand corner are two of its substrates, ATP and...
    101 KB (11,357 words) - 21:37, 30 July 2024
  • Thumbnail for Glucose
    GLUT proteins. In the other cell types, phosphorylation occurs through a hexokinase, whereupon glucose can no longer diffuse out of the cell. The glucose...
    121 KB (12,794 words) - 10:50, 6 August 2024
  • Thumbnail for HKDC1
    Hexokinase domain containing 1 (HKDC1) is an enzyme which in humans is encoded by the HKDC1 gene on chromosome 10. It is a recently discovered hexokinase...
    5 KB (572 words) - 15:32, 1 April 2024
  • Thumbnail for Glucose 6-phosphate
    phosphorylation of glucose on the sixth carbon. This is catalyzed by the enzyme hexokinase in most cells, and, in higher animals, glucokinase in certain cells, most...
    10 KB (966 words) - 20:48, 1 February 2024
  • Thumbnail for Enzyme
    enzyme is fully specified by four numerical designations. For example, hexokinase (EC 2.7.1.1) is a transferase (EC 2) that adds a phosphate group (EC 2...
    96 KB (9,819 words) - 12:03, 26 July 2024
  • Thumbnail for Positron emission tomography
    analog that is taken up by glucose-using cells and phosphorylated by hexokinase (whose mitochondrial form is significantly elevated in rapidly growing...
    73 KB (8,763 words) - 04:19, 2 July 2024
  • Thumbnail for Adenosine triphosphate
    produces additional equivalents of ATP.[citation needed] In glycolysis, hexokinase is directly inhibited by its product, glucose-6-phosphate, and pyruvate...
    49 KB (5,446 words) - 08:06, 23 August 2024
  • Thumbnail for Fluorine
    Aerobic Glycolysis of Rat Hepatoma Cells in Culture: Role of Mitochondrial Hexokinase". Proceedings of the National Academy of Sciences. 74 (9): 3735–3739....
    157 KB (15,346 words) - 06:59, 24 August 2024
  • Thumbnail for Glycogenolysis
    The glucose is subsequently phosphorylated to glucose-6-phosphate by hexokinase. Glycogen phosphorylase with Pyridoxal phosphate as prosthetic group Alpha-1...
    6 KB (673 words) - 13:58, 23 August 2024
  • non-competitive inhibition is given by glucose-6-phosphate inhibiting hexokinase in the brain. Carbons 2 and 4 on glucose-6-phosphate contain hydroxyl...
    14 KB (1,809 words) - 08:49, 29 June 2024
  • Thumbnail for Insulin
    (G-6-P) by glucokinase (hexokinase IV) which is not inhibited by G-6-P in the way that the hexokinases in other tissues (hexokinase I – III) are affected...
    121 KB (13,799 words) - 18:32, 22 August 2024
  • Thumbnail for Mannose
    polysaccharides and glycoproteins yields mannose, which is phosphorylated by hexokinase to generate mannose-6-phosphate. Mannose-6-phosphate is converted to...
    17 KB (1,686 words) - 20:34, 22 August 2024
  • Thumbnail for Fluorodeoxyglucose (18F)
    brain. [18F]FDG is taken up by cells, and subsequently phosphorylated by hexokinase (whose mitochondrial form is greatly elevated in rapidly growing malignant...
    22 KB (2,363 words) - 19:12, 26 June 2024
  • 0.7355 kW) Hefnerkerze, an old photometric unit of luminous intensity Hexokinase, an enzyme Sobolev space Hk, in mathematics .hk, Hong Kong's country top-level...
    2 KB (261 words) - 19:29, 1 July 2024