Hyaluronidases are a family of enzymes that catalyse the degradation of hyaluronic acid. Karl Meyer classified these enzymes in 1971, into three distinct...
31 KB (2,896 words) - 02:10, 16 July 2024
Trastuzumab/hyaluronidase, sold under the brand name Herceptin SC among others, is a fixed-dose combination medication for the treatment of HER2-overexpressing...
11 KB (703 words) - 18:13, 27 March 2024
Daratumumab/hyaluronidase, sold under the brand name Darzalex Faspro, is a fixed-dose combination medication for the treatment of adults with newly diagnosed...
10 KB (884 words) - 05:10, 10 July 2024
Efgartigimod alfa/hyaluronidase, sold under the brand name Vyvgart Hytrulo, is a coformulation medication used for the treatment of generalized myasthenia...
6 KB (425 words) - 07:18, 25 June 2024
Pertuzumab/trastuzumab/hyaluronidase, sold under the brand name Phesgo, is a fixed-dose combination medication to treat adults with HER2-positive breast...
12 KB (966 words) - 04:46, 15 July 2024
Rituximab (redirect from Rituximab and hyaluronidase human)
Waldenström's macroglobulinemia, a type of NHL. Rituximab in combination with hyaluronidase human, sold under the brand names MabThera SC and Rituxan Hycela, is...
56 KB (5,018 words) - 05:06, 23 July 2024
Hyaluronidase deficiency is a condition caused by mutations in the HYAL1 gene, and is characterized by multiple soft-tissue masses.: 544 As hyaluronidase...
3 KB (147 words) - 13:03, 4 June 2024
primarily focused on its proprietary and patented recombinant human hyaluronidase enzyme, rHuPH20. The company's development pipeline is concentrated...
10 KB (1,024 words) - 07:02, 7 July 2024
sulphate and hyaluronan can be shed of the endothelial layer by enzymes. Hyaluronidase, hepararanse/heparinase, matrix and membrane-type matrix metalloproteases...
19 KB (2,190 words) - 09:59, 2 June 2024
PMID 22050223. S2CID 207441558. Starr CR, Engleberg NC (January 2006). "Role of hyaluronidase in subcutaneous spread and growth of group A streptococcus". Infection...
40 KB (3,950 words) - 04:18, 20 May 2024
acid)). Two published medical journals appear to show Hyaluronidase injections (Hyaluronidase is an enzyme used to dissolve hyaluronic acid which is...
11 KB (1,105 words) - 12:59, 2 June 2024
phospholipase A2, hyaluronidase and acid phosphatase. The three proteins in honeybee venom that are important allergens are phospholipase A2, hyaluronidase and acid...
14 KB (1,582 words) - 19:43, 29 June 2024
placental mammals, the acrosome contains degradative enzymes (including hyaluronidase and acrosin). These enzymes break down the outer membrane of the ovum...
4 KB (423 words) - 09:32, 16 February 2024
bruised. Hyaluronic acid "bruising" may be treated using injections of hyaluronidase enzyme around the location. Other common medication-specific side effects...
22 KB (2,581 words) - 08:38, 3 December 2023
degraded by a family of enzymes called hyaluronidases. In humans, there are at least seven types of hyaluronidase-like enzymes, several of which are tumor...
50 KB (5,491 words) - 13:36, 29 June 2024
subgenus of Vespula The venom of Vespula is mostly composed of antigen 5, hyaluronidase, and phospholipase. A high degree of similarity occurs between immunogenic...
9 KB (738 words) - 01:28, 7 November 2023
Hyaluronidase-2 is a multifunctional protein, previously thought to only possess acid-active hyaluronan-degrading enzymatic function. In humans it is...
10 KB (1,152 words) - 16:25, 1 February 2024
instance, the figure to the right shows 3 spliceforms from the mouse hyaluronidase 3 gene. Comparing the exonic structure shown in the first line (green)...
62 KB (7,809 words) - 17:56, 21 May 2024
fibrinogen to fibrin to cause clots which is important in skin infections. Hyaluronidase (also known as spreading factor) breaks down hyaluronic acid and helps...
114 KB (12,744 words) - 15:07, 22 July 2024
present in myasthenia gravis. It is also available coformulated with hyaluronidase. The most common side effects include respiratory tract infections,...
17 KB (1,326 words) - 07:06, 25 June 2024
in Man (OMIM): 601492) had been reported. The disorder results from hyaluronidase deficiency. Symptoms included nodular soft-tissue masses located around...
27 KB (3,034 words) - 07:13, 15 April 2024
Acetoin Negative Acid Phosphatase Variable Alkaline Phosphatase Positive Hyaluronidase Negative β-D-glucosidase Positive Leucine aminopeptidase Positive Neuraminidase...
6 KB (551 words) - 03:52, 23 October 2023
peptides. Further protein components include apamin (2%), a neurotoxin, hyaluronidase (2%), which dilates blood vessels, increasing their permeability and...
6 KB (606 words) - 17:26, 31 May 2024
the GalT initiates the acrosome reaction. This process releases the hyaluronidase that digests the matrix of hyaluronic acid in the vestments around the...
45 KB (5,218 words) - 18:46, 4 July 2024
variety of enzymes which cause damage to host tissues. Enzymes include hyaluronidase, which breaks down the connective tissue component hyaluronic acid;...
15 KB (1,871 words) - 07:36, 25 March 2024
Hyaluronidase-1 is an enzyme that in humans is encoded by the HYAL1 gene. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly...
17 KB (2,105 words) - 17:46, 7 July 2024
family of antibiotics that inhibits the hydrolysis of hyaluronic acid by hyaluronidase. It has been isolated from cultures of Streptomyces hyaluromycini. Harunari...
3 KB (113 words) - 13:16, 19 June 2024
Graafian follicle. For fertilization to occur, sperm cells rely on hyaluronidase (an enzyme found in the acrosome of spermatozoa) to disperse the corona...
3 KB (247 words) - 05:54, 27 June 2024
affect the body in different ways. Almost all snake venom contains hyaluronidase, an enzyme that ensures rapid diffusion of the venom.: 243 Venomous...
151 KB (15,099 words) - 23:43, 23 July 2024
Beta-N-acetylglucosaminidase - - + Beta-N-galactosaminidase - - + Sialidase - - + Beta-galactosidase - - + Beta-glucosidase - + +/- Hyaluronidase + - +...
7 KB (712 words) - 21:42, 18 December 2023