The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses...

on the type of receptor through which they signal, human interferons have been classified into three major types. Interferon type I: All type I IFNs bind...

Interferon gamma (IFNG or IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon...

respond to a select group of cytokines including interferon type I, interferon type II, interferon type III. and members of the interleukin-10 family These...

are three known types of interferon. With approximately 450 genes highly expressed in response to interferon type I. Type I interferon consists of INF-α...

The type III interferon group is a group of anti-viral cytokines, that consists of four IFN-λ (lambda) molecules called IFN-λ1, IFN-λ2, IFN-λ3 (also known...

type I interferon production when cells are infected with intracellular pathogens, such as viruses, mycobacteria and intracellular parasites. Type I interferon...

The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human...

recently reviewed. There are 3 types of IFNs: Interferon type I, Interferon type II and Interferon type III. The type II IFN, also called IFNγ, is produced...

'movement'. Interferon-alpha, an interferon type I, was identified in 1957 as a protein that interfered with viral replication. The activity of interferon-gamma...

Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian...

proliferation of further CD4+ Th1 cells. CD4+ T cells secrete IL-2 and interferon gamma (IFNγ), inducing the further release of other Th1 cytokines, thus...

for the inflammatory process. This may be due to the production of Interferon type I that inhibits the CRP production in liver cells during SLE. CRP is...

2009). "Mechanisms of evasion of the type I interferon antiviral response by flaviviruses". Journal of Interferon & Cytokine Research. 29 (9): 521–30....

leads to production of inflammatory cytokines as well as type I interferons (interferon type I) to help fight viral infection. The adapter proteins and...

counter. Cholecalciferol (vitamin D3) appears to stimulate the body's interferon type I signaling system that protects against bacteria and viruses, unlike...

mechanism of action of dexamethasone involves suppression of late-stage interferon type I programs in severe COVID-19 patients. Dexamethasone is used fairly...

Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon...

Walkiewicz, Magdalena (2024-05-30). "The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1". New England Journal of Medicine. 390 (20): 1873–1884...

showed that they cause an increase in cell death and the production of interferon type I (an inflammatory mediator). In vitro, gluten alters cellular morphology...

Interferon regulatory factors (IRF) are proteins which regulate transcription of interferons (see regulation of gene expression). Interferon regulatory...

dendritic cells (pDCs) are a rare type of immune cell that are known to secrete large quantities of type 1 interferon (IFNs) in response to a viral infection...

erythematosus. It binds to the type I interferon receptor, blocking the activity of type I interferons such as interferon-α and interferon-β.[medical citation needed]...

RIG-I (retinoic acid-inducible gene I) is a cytosolic pattern recognition receptor (PRR) that can mediate induction of a type-I interferon (IFN1) response...

phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity...

Interferon tau (IFNτ, IFNT) is a Type I interferon made of a single chain of amino acids. IFN-τ was first discovered in ruminants as the signal for the...

Interferon-stimulated gene 15 (ISG15) is a 17 kDA secreted protein that in humans is encoded by the ISG15 gene. ISG15 is induced by type I interferon...

recessive types of osteogenesis imperfecta. Defects in the proteins pigment epithelium-derived factor (PEDF) and bone-restricted interferon-induced transmembrane...

Interferome Interferon Interferon beta 1a Interferon beta 1b Interferon gamma Interferon type I Interferon type II Interferon type III Interferon-alpha/beta...

Interleukin-28 receptor is a type II cytokine receptor found largely in epithelial cells. It binds type 3 interferons, interleukin-28 A (Interferon lambda 1), Interleukin-28B...