JWH-018 (1-pentyl-3-(1-naphthoyl)indole, NA-PIMO or AM-678) is an analgesic chemical from the naphthoylindole family that acts as a full agonist at both...
33 KB (2,713 words) - 06:29, 11 July 2024
screening of the synthetic cannabinoids JWH-018, JWH-073, JWH-398, JWH-200, JWH-019, JWH-122, JWH-081, JWH-250, JWH-203, CP-47,497, CP-47,497-C8, HU-210...
123 KB (12,050 words) - 11:29, 14 August 2024
the potency of JWH-018 in rats, suggesting potent cannabinoid-like activity. AM-2201 metabolism differs only slightly from that of JWH-018. AM-2201 N-dealkylation...
7 KB (485 words) - 14:37, 22 January 2024
Tetrahydrocannabiphorol (redirect from JWH-091)
The Δ8 isomer is also known as a synthetic cannabinoid under the code name JWH-091. It's unconfirmed whether or not Δ8-THCP is found naturally in cannabis...
8 KB (693 words) - 05:40, 4 August 2024
activated β-arrestin 2 recruitment) than JWH-018 (25.3 nM, 100%) with over 10x the binding affinity than JWH-018 in vitro. In a review of in vitro MDMB-4en-PINACA...
18 KB (1,959 words) - 14:26, 31 July 2024
FUB-JWH-018 (also known as FUB-018) is a naphthoylindole-based synthetic cannabinoid, representing a molecular hybrid of JWH-018 and AB-FUBICA or ADB-FUBICA...
3 KB (180 words) - 10:48, 23 April 2022
responsible for JWH-018 and JWH-073 metabolites’ conjugation and had high affinity for hydroxylated metabolites (Km=12–18 mmol/L). Generation of JWH-018-N-4- and...
25 KB (2,877 words) - 22:38, 8 December 2023
seized after the legal ban on JWH-018 had gone into effect in Germany, were shown to contain the unregulated compound JWH-073 instead. Analgesic effects...
12 KB (981 words) - 12:16, 8 June 2024
used for smoking cessation Other notable synthetic cannabinoids include: JWH-018, a potent synthetic cannabinoid agonist discovered by John W. Huffman at...
73 KB (7,813 words) - 11:31, 14 August 2024
known drugs, but have completely dissimilar chemical structures (e.g. JWH-018 vs THC). Despite being a very broad term, applicable to almost every synthetic...
37 KB (4,432 words) - 10:18, 15 August 2024
HU-345 JWH-x JWH-007 JWH-015 JWH-018 JWH-019 JWH-030 JWH-047 JWH-048 JWH-051 JWH-057 JWH-073 JWH-081 JWH-098 JWH-116 JWH-120 JWH-122 JWH-133 JWH-139 JWH-147...
41 KB (4,360 words) - 21:40, 11 August 2024
different spot inside of the CB1 receptor than synthetic cannabinoid such JWH-018. This may explain the latter's toxicity. The partial synthesis of ∆8-THC...
48 KB (4,847 words) - 13:57, 29 July 2024
linker at the indole 3-position, rather than the precedented ketone of JWH-018 and its analogs, or the amide of APICA and its analogs. PB-22 has an EC50...
8 KB (753 words) - 05:21, 18 May 2023
APICA to have an IC50 of 175 nM at CB1, only slightly less potent than JWH-018 which had an IC50 of 169 nM, but over four times more tightly binding than...
6 KB (593 words) - 19:12, 16 July 2024
Journal of Neuroimmune Pharmacology. 13 (4): 438–52. doi:10.1007/s11481-018-9782-9. PMC 6223748. PMID 29556883. Colizzi M, McGuire P, Pertwee RG, Bhattacharyya...
165 KB (17,240 words) - 08:04, 14 August 2024
THJ-018 (SGT-17) is a synthetic cannabinoid that is the indazole analogue of JWH-018 and has been sold online as a designer drug. THJ-018 acts as a full...
3 KB (211 words) - 09:50, 24 November 2023
JWH-016 JWH-018 JWH-019 JWH-020 JWH-042 JWH-043 JWH-046 JWH-047 JWH-048 JWH-049 JWH-050 JWH-070 JWH-072 JWH-073 JWH-076 JWH-077 JWH-079 JWH-080 JWH-081...
123 KB (11,364 words) - 11:37, 16 August 2024
HU-345 JWH-x JWH-007 JWH-015 JWH-018 JWH-019 JWH-030 JWH-047 JWH-048 JWH-051 JWH-057 JWH-073 JWH-081 JWH-098 JWH-116 JWH-120 JWH-122 JWH-133 JWH-139 JWH-147...
46 KB (4,520 words) - 17:04, 13 August 2024
cannabinoids AM AM-2201 CP CP-55940 Dimethylheptylpyran HU HU-210 HU-331 JWH JWH-018 JWH-073 JWH-133 Levonantradol MDMB-CHMICA SR144528 WIN 55,212-2 Pharmacology...
16 KB (1,619 words) - 15:47, 7 August 2024
JWH-051 JWH-056 JWH-057 JWH-065 JWH-091 JWH-102 JWH-103 JWH-124 JWH-130 JWH-133 JWH-138 JWH-139 JWH-142 JWH-143 JWH-161 JWH-186 JWH-187 JWH-188 JWH-189...
11 KB (1,118 words) - 13:12, 12 April 2024
cannabinoids AM AM-2201 CP CP-55940 Dimethylheptylpyran HU HU-210 HU-331 JWH JWH-018 JWH-073 JWH-133 Levonantradol MDMB-CHMICA SR144528 WIN 55,212-2 Pharmacology...
12 KB (1,179 words) - 09:38, 16 June 2024
of SDB-001, just as AM-2201 is the terminally-fluorinated analogue of JWH-018, and XLR-11 is the terminally-fluorinated analogue of UR-144. STS-135 acts...
4 KB (310 words) - 00:22, 5 May 2022
cannabinoids AM AM-2201 CP CP-55940 Dimethylheptylpyran HU HU-210 HU-331 JWH JWH-018 JWH-073 JWH-133 Levonantradol MDMB-CHMICA SR144528 WIN 55,212-2 Pharmacology...
3 KB (254 words) - 03:59, 6 June 2024
Dronabinol, the name of THC-based pharmaceutical (INN) HU-210, WIN 55,212-2, JWH-133, synthetic cannabinoid agonists (neocannabinoids) Nabilone, a novel synthetic...
57 KB (5,420 words) - 11:32, 16 August 2024
JWH-210 is an analgesic chemical from the naphthoylindole family, which acts as a potent cannabinoid agonist at both the CB1 and CB2 receptors, with Ki...
6 KB (491 words) - 23:17, 18 September 2023
synthetic cannabinoid compound JWH-018. Unlike the butyl homolog JWH-073, which is several times weaker than JWH-018, the hexyl homolog is only slightly...
5 KB (414 words) - 11:20, 16 February 2023
ingredients (C8)-CP 47,497 and JWH-018. An ELISA immunoassay technique for detecting JWH-250 in urine has been reported. JWH-250 is considered a Schedule...
7 KB (542 words) - 14:20, 24 March 2024
HU-345 JWH-x JWH-007 JWH-015 JWH-018 JWH-019 JWH-030 JWH-047 JWH-048 JWH-051 JWH-057 JWH-073 JWH-081 JWH-098 JWH-116 JWH-120 JWH-122 JWH-133 JWH-139 JWH-147...
19 KB (1,577 words) - 14:45, 1 July 2024
Journal of Neuroimmune Pharmacology. 13 (4): 438–452. doi:10.1007/s11481-018-9782-9. PMC 6223748. PMID 29556883. Wenger T, Moldrich G, Furst S (July 2003)...
75 KB (8,572 words) - 10:04, 8 July 2024
derivative of JWH-007, JWH-018, has slightly higher binding affinity for CB1, with an optimum binding of 9.00 nM at CB1 and 2.94 nM at CB2, and JWH-007 displayed...
7 KB (640 words) - 04:44, 26 December 2023