• Thumbnail for Messenger RNA
    Messenger RNA (redirect from MRNA)
    In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is...
    51 KB (6,183 words) - 06:38, 23 January 2025
  • Thumbnail for MRNA vaccine
    An mRNA vaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The vaccine delivers molecules...
    78 KB (8,024 words) - 03:59, 6 January 2025
  • Thumbnail for MRNA display
    mRNA display is a display technique used for in vitro protein, and/or peptide evolution to create molecules that can bind to a desired target. The process...
    16 KB (2,214 words) - 17:06, 8 June 2024
  • mRNA (or messenger RNA) is ribonucleic acid (RNA) that is read by the ribosome to produce a protein. mRNA may also refer to: Mitochondrial DNA (mDNA)...
    314 bytes (76 words) - 17:16, 10 October 2023
  • Thumbnail for Moderna COVID-19 vaccine
    those with high-risk medical conditions. It is an mRNA vaccine composed of nucleoside-modified mRNA (modRNA) encoding a spike protein of SARS-CoV-2, which...
    177 KB (13,698 words) - 16:52, 23 October 2024
  • Thumbnail for Exon
    Exon (redirect from MRNA exon)
    excluded from mature mRNA transcripts by blocking the access of splice-directing small nuclear ribonucleoprotein particles (snRNPs) to pre-mRNA using Morpholino...
    13 KB (1,519 words) - 18:34, 31 December 2024
  • Thumbnail for Translation (biology)
    anticodon sequences to mRNA codons. The tRNAs carry specific amino acids that are chained together into a polypeptide as the mRNA passes through and is...
    36 KB (4,225 words) - 22:34, 30 January 2025
  • mRNA-4157/V940 is an mRNA based cancer vaccine encapsulated in solid lipid nanoparticles. The 34 mRNA sequences in mRNA-4157/V940 vaccine were generated...
    9 KB (899 words) - 02:27, 8 November 2024
  • Thumbnail for Lipid-based nanoparticle
    specific type of lipid-based nanoparticle, such as the LNPs used for the mRNA vaccine. Using LNPs for drug delivery was first approved in 2018 for the...
    26 KB (2,899 words) - 22:15, 18 January 2025
  • more than a decade to develop. In contrast, mRNA is a molecule that can be made quickly, and research on mRNA to fight diseases was begun decades before...
    206 KB (23,699 words) - 00:45, 1 February 2025
  • Thumbnail for Post-transcriptional modification
    correct translation of eukaryotic genomes because the initial precursor mRNA produced by transcription often contains both exons (coding sequences) and...
    11 KB (1,432 words) - 23:35, 24 July 2024
  • Thumbnail for RNA-Seq
    RNA-Seq (redirect from MRNA-seq)
    differences in gene expression in different groups or treatments. In addition to mRNA transcripts, RNA-Seq can look at different populations of RNA to include...
    103 KB (11,110 words) - 12:52, 25 January 2025
  • Thumbnail for Methamphetamine
    administration of METH has been shown to upregulate σ-1 receptor protein and mRNA in various brain regions including the substantia nigra, frontal cortex,...
    169 KB (16,495 words) - 23:47, 26 January 2025
  • In enzymology, a mRNA guanylyltransferase (EC 2.7.7.50) is an enzyme that catalyzes the chemical reaction GTP + (5')ppPur-mRNA ⇌ {\displaystyle \rightleftharpoons...
    3 KB (319 words) - 15:00, 26 August 2023
  • Thumbnail for Transcription (biology)
    transcribed into RNA molecules that can encode proteins, called messenger RNA (mRNA). Other segments of DNA are transcribed into RNA molecules called non-coding...
    59 KB (6,898 words) - 15:03, 31 January 2025
  • Thumbnail for MRNA-1283
    mRNA-1283 is a COVID-19 vaccine candidate developed by Moderna. Compared to prior mRNA vaccines, this candidate has a storage temperature of 2-5 °C, compatible...
    5 KB (387 words) - 20:39, 30 May 2024
  • Thumbnail for Protein biosynthesis
    produced in a premature form (pre-mRNA) which undergoes post-transcriptional modifications to produce mature mRNA. The mature mRNA is exported from the cell nucleus...
    40 KB (4,349 words) - 13:44, 31 December 2024
  • Thumbnail for MDMA
    (Green et al., 2003). MDMA downregulates SERT function without altering SERT mRNA or protein expression, and this rapid downregulation is sustained for at...
    235 KB (22,515 words) - 07:12, 1 February 2025
  • Antisense RNA is complementary to coding mRNA and is used to trigger mRNA inactivation to prevent the mRNA from being used in protein translation. RNAi-based...
    77 KB (8,887 words) - 03:21, 29 October 2024
  • Thumbnail for RNA splicing
    RNA splicing (redirect from MRNA splicing)
    a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger RNA (mRNA). It works by removing all the introns (non-coding...
    38 KB (4,660 words) - 04:10, 9 November 2024
  • mRNA surveillance mechanisms are pathways utilized by organisms to ensure fidelity and quality of messenger RNA (mRNA) molecules. There are a number of...
    29 KB (3,394 words) - 21:28, 16 March 2024
  • theory alleging that people vaccinated against COVID-19, especially with mRNA vaccines, are suffering from a high incidence of fast-developing cancers...
    7 KB (671 words) - 16:34, 31 January 2025
  • which are: the two ribosomal subunits (50S and 30S subunits); the mature mRNA to be translated; the tRNA charged with N-formylmethionine (the first amino...
    23 KB (2,926 words) - 04:10, 2 November 2024
  • Thumbnail for DNA
    region; these are the TAG, TAA, and TGA codons, (UAG, UAA, and UGA on the mRNA). Cell division is essential for an organism to grow, but, when a cell divides...
    166 KB (17,847 words) - 23:51, 29 January 2025
  • Thumbnail for Virus
    complementary to the viral messenger RNA (mRNA). Positive-sense viral RNA is in the same sense as viral mRNA and thus at least a part of it can be immediately...
    154 KB (18,247 words) - 12:10, 1 February 2025
  • Thumbnail for Vitamin D
    complex recruits other proteins that transcribe the downstream gene into mRNA which in turn is translated into protein causing a change in cell function...
    164 KB (18,311 words) - 00:06, 28 January 2025
  • Thumbnail for Human metapneumovirus
    and Immunogenicity of mRNA-1653 in Healthy Adults" at ClinicalTrials.gov "Moderna to Present Data from Two of Its Prophylactic mRNA Vaccines at IDWeek 2019"...
    39 KB (4,468 words) - 06:53, 1 February 2025
  • Thumbnail for Alternative splicing
    the calcitonin mRNA contains exons 1–4, and terminates after a polyadenylation site in exon 4. Another mRNA is produced from this pre-mRNA by skipping exon...
    62 KB (7,813 words) - 20:10, 31 January 2025
  • Thumbnail for Malaria
    vaccine with at least 75% efficacy. Germany-based BioNTECH SE is developing an mRNA-based malaria vaccine BN165 which has recently initiated a Phase 1 study...
    253 KB (26,234 words) - 08:51, 28 January 2025
  • Thumbnail for Ribosome
    sequence of the amino acids in a protein is transcribed into a messenger RNA (mRNA) chain. Ribosomes bind to the messenger RNA molecules and use the RNA's sequence...
    65 KB (7,283 words) - 14:07, 9 January 2025