Messenger RNA (redirect from MRNA)
In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is...
51 KB (6,183 words) - 06:38, 23 January 2025
An mRNA vaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The vaccine delivers molecules...
78 KB (8,024 words) - 03:59, 6 January 2025
mRNA display is a display technique used for in vitro protein, and/or peptide evolution to create molecules that can bind to a desired target. The process...
16 KB (2,214 words) - 17:06, 8 June 2024
mRNA (or messenger RNA) is ribonucleic acid (RNA) that is read by the ribosome to produce a protein. mRNA may also refer to: Mitochondrial DNA (mDNA)...
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Moderna COVID-19 vaccine (redirect from MRNA-1273)
those with high-risk medical conditions. It is an mRNA vaccine composed of nucleoside-modified mRNA (modRNA) encoding a spike protein of SARS-CoV-2, which...
177 KB (13,698 words) - 16:52, 23 October 2024
Translation (biology) (redirect from Mrna translation)
anticodon sequences to mRNA codons. The tRNAs carry specific amino acids that are chained together into a polypeptide as the mRNA passes through and is...
36 KB (4,225 words) - 22:34, 30 January 2025
mRNA-4157/V940 is an mRNA based cancer vaccine encapsulated in solid lipid nanoparticles. The 34 mRNA sequences in mRNA-4157/V940 vaccine were generated...
9 KB (899 words) - 02:27, 8 November 2024
Lipid-based nanoparticle (redirect from MRNA-lipid nanoparticle)
specific type of lipid-based nanoparticle, such as the LNPs used for the mRNA vaccine. Using LNPs for drug delivery was first approved in 2018 for the...
26 KB (2,899 words) - 22:15, 18 January 2025
COVID-19 vaccine (redirect from COVID-19 mRNA vaccine (nucleoside-modified))
more than a decade to develop. In contrast, mRNA is a molecule that can be made quickly, and research on mRNA to fight diseases was begun decades before...
206 KB (23,699 words) - 00:45, 1 February 2025
Post-transcriptional modification (redirect from Pre-mRNA processing)
correct translation of eukaryotic genomes because the initial precursor mRNA produced by transcription often contains both exons (coding sequences) and...
11 KB (1,432 words) - 23:35, 24 July 2024
administration of METH has been shown to upregulate σ-1 receptor protein and mRNA in various brain regions including the substantia nigra, frontal cortex,...
169 KB (16,495 words) - 23:47, 26 January 2025
In enzymology, a mRNA guanylyltransferase (EC 2.7.7.50) is an enzyme that catalyzes the chemical reaction GTP + (5')ppPur-mRNA ⇌ {\displaystyle \rightleftharpoons...
3 KB (319 words) - 15:00, 26 August 2023
Transcription (biology) (redirect from MRNA biosynthesis (bacteria))
transcribed into RNA molecules that can encode proteins, called messenger RNA (mRNA). Other segments of DNA are transcribed into RNA molecules called non-coding...
59 KB (6,898 words) - 15:03, 31 January 2025
mRNA-1283 is a COVID-19 vaccine candidate developed by Moderna. Compared to prior mRNA vaccines, this candidate has a storage temperature of 2-5 °C, compatible...
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produced in a premature form (pre-mRNA) which undergoes post-transcriptional modifications to produce mature mRNA. The mature mRNA is exported from the cell nucleus...
40 KB (4,349 words) - 13:44, 31 December 2024
(Green et al., 2003). MDMA downregulates SERT function without altering SERT mRNA or protein expression, and this rapid downregulation is sustained for at...
235 KB (22,515 words) - 07:12, 1 February 2025
RNA therapeutics (redirect from MRNA therapeutic)
Antisense RNA is complementary to coding mRNA and is used to trigger mRNA inactivation to prevent the mRNA from being used in protein translation. RNAi-based...
77 KB (8,887 words) - 03:21, 29 October 2024
RNA splicing (redirect from MRNA splicing)
a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger RNA (mRNA). It works by removing all the introns (non-coding...
38 KB (4,660 words) - 04:10, 9 November 2024
mRNA surveillance mechanisms are pathways utilized by organisms to ensure fidelity and quality of messenger RNA (mRNA) molecules. There are a number of...
29 KB (3,394 words) - 21:28, 16 March 2024
theory alleging that people vaccinated against COVID-19, especially with mRNA vaccines, are suffering from a high incidence of fast-developing cancers...
7 KB (671 words) - 16:34, 31 January 2025
Bacterial translation (redirect from MRNA-ribosome)
which are: the two ribosomal subunits (50S and 30S subunits); the mature mRNA to be translated; the tRNA charged with N-formylmethionine (the first amino...
23 KB (2,926 words) - 04:10, 2 November 2024
region; these are the TAG, TAA, and TGA codons, (UAG, UAA, and UGA on the mRNA). Cell division is essential for an organism to grow, but, when a cell divides...
166 KB (17,847 words) - 23:51, 29 January 2025
complementary to the viral messenger RNA (mRNA). Positive-sense viral RNA is in the same sense as viral mRNA and thus at least a part of it can be immediately...
154 KB (18,247 words) - 12:10, 1 February 2025
complex recruits other proteins that transcribe the downstream gene into mRNA which in turn is translated into protein causing a change in cell function...
164 KB (18,311 words) - 00:06, 28 January 2025
and Immunogenicity of mRNA-1653 in Healthy Adults" at ClinicalTrials.gov "Moderna to Present Data from Two of Its Prophylactic mRNA Vaccines at IDWeek 2019"...
39 KB (4,468 words) - 06:53, 1 February 2025
Alternative splicing (redirect from Alternate mRNA splicing)
the calcitonin mRNA contains exons 1–4, and terminates after a polyadenylation site in exon 4. Another mRNA is produced from this pre-mRNA by skipping exon...
62 KB (7,813 words) - 20:10, 31 January 2025
vaccine with at least 75% efficacy. Germany-based BioNTECH SE is developing an mRNA-based malaria vaccine BN165 which has recently initiated a Phase 1 study...
253 KB (26,234 words) - 08:51, 28 January 2025
sequence of the amino acids in a protein is transcribed into a messenger RNA (mRNA) chain. Ribosomes bind to the messenger RNA molecules and use the RNA's sequence...
65 KB (7,283 words) - 14:07, 9 January 2025