• Thumbnail for Methionine synthase
    Methionine synthase (MS, MeSe, MTR) is primarily responsible for the regeneration of methionine from homocysteine in most individuals. In humans it is...
    30 KB (3,437 words) - 07:25, 16 May 2024
  • Thumbnail for Methionine
    (3) Adenosylhomocysteinase cysteine. Methionine can be regenerated from homocysteine via (4) methionine synthase in a reaction that requires vitamin B12...
    30 KB (3,080 words) - 04:32, 17 December 2024
  • Thumbnail for Homocystinuria
    the metabolism of the amino acid methionine due to a deficiency of cystathionine beta synthase or methionine synthase. It is an inherited autosomal recessive...
    13 KB (1,363 words) - 21:19, 25 December 2024
  • Thumbnail for Vitamin B12
    neurotoxic dicarboxylic acid, causing neurological deterioration. Methionine synthase, coded by MTR gene, is a methyltransferase enzyme which uses the...
    115 KB (12,597 words) - 20:32, 29 December 2024
  • Thumbnail for (Methionine synthase) reductase
    [Methionine synthase] reductase, or Methionine synthase reductase, encoded by the gene MTRR, is an enzyme that is responsible for the reduction of methionine...
    5 KB (528 words) - 12:18, 26 August 2023
  • Thumbnail for MTRR (gene)
    Methionine synthase reductase, also known as MSR, is an enzyme that in humans is encoded by the MTRR gene. Methionine is an essential amino acid required...
    44 KB (5,274 words) - 18:33, 3 May 2024
  • N-methylhistidine, and two isomers of N-methylarginine. Methionine synthase regenerates methionine (Met) from homocysteine (Hcy). The overall reaction transforms...
    28 KB (3,059 words) - 02:30, 24 December 2024
  • Thumbnail for Transsulfuration pathway
    conversion of this intermediate to methionine, through a methylation reaction carried out by methionine synthase. The reverse pathway is present in several...
    6 KB (831 words) - 00:32, 17 October 2024
  • Thumbnail for Levomefolic acid
    10-methylenetetrahydrofolate (MTHF) and used to recycle homocysteine back to methionine by methionine synthase (MS). L-Methylfolate is water-soluble and primarily excreted...
    15 KB (1,173 words) - 11:42, 25 June 2024
  • Thumbnail for Cyanocobalamin
    Methylcobalamin and 5-methyltetrahydrofolate are needed by methionine synthase in the methionine cycle to transfer a methyl group from 5-methyltetrahydrofolate...
    30 KB (2,663 words) - 21:59, 11 November 2024
  • Thumbnail for Homocysteine
    back into L-methionine or conversion to L-cysteine. Mammals biosynthesize the amino acid cysteine via homocysteine. Cystathionine β-synthase catalyses the...
    25 KB (2,076 words) - 23:05, 15 December 2024
  • Thumbnail for Methylenetetrahydrofolate reductase
    toxic amino acid) to methionine by the enzyme methionine synthase. (Note that homocysteine can also be converted to methionine by the folate-independent...
    35 KB (3,743 words) - 21:22, 25 December 2024
  • Thumbnail for Copper deficiency
    range of macromolecules by the suspected copper-dependent enzyme methionine synthase. This cycle is able to produce purines, which are a component of...
    28 KB (2,727 words) - 20:58, 2 January 2025
  • Thumbnail for Hyperhomocysteinemia
    homocysteine [citation needed] is converted back to methionine by remethylation via the methionine synthase major pathway. This requires active folate and...
    20 KB (2,117 words) - 21:19, 25 December 2024
  • Thumbnail for Trimethylglycine
    back to methionine can occur via either of two pathways. The pathway present in virtually all cells involves the enzyme methionine synthase (MS), which...
    22 KB (1,809 words) - 14:31, 19 December 2024
  • Thumbnail for S-Adenosyl methionine
    recycled back to methionine through transfer of a methyl group from 5-methyltetrahydrofolate, by one of the two classes of methionine synthases (i.e. cobalamin-dependent...
    24 KB (2,420 words) - 14:11, 17 December 2024
  • Thumbnail for Hydroxocobalamin
    metabolism, and the activation of methionine synthase, which is the rate-limiting step in the synthesis of methionine from homocysteine and 5-methyltetrahydrofolate...
    21 KB (2,021 words) - 01:38, 28 August 2024
  • Thumbnail for Vitamin B12 deficiency
    B12 is a necessary cofactor for methionine synthase, an enzyme involved in the methylation of homocysteine to methionine. DNA methylation is involved in...
    117 KB (12,927 words) - 11:25, 10 December 2024
  • Thumbnail for Cystathionine beta synthase
    Cystathionine-β-synthase, also known as CBS, is an enzyme (EC 4.2.1.22) that in humans is encoded by the CBS gene. It catalyzes the first step of the transsulfuration...
    26 KB (3,182 words) - 21:20, 25 December 2024
  • using the enzyme methionine S-methyltransferase and the catalyst methionine synthase. Phenylalanine and tyrosine are grouped together because tyrosine...
    27 KB (2,685 words) - 11:38, 3 December 2024
  • Thumbnail for Methylcobalamin
    5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), also known as methionine synthase.[citation needed] Methylcobalamin participates in the Wood-Ljungdahl...
    12 KB (1,015 words) - 20:21, 29 December 2024
  • Thumbnail for Rowena Green Matthews
    2009). "Oxidation of cysteine 645 of cobalamin-independent methionine synthase causes a methionine limitation in Escherichia coli". Journal of Bacteriology...
    15 KB (1,327 words) - 22:27, 27 November 2024
  • Thumbnail for Methyltransferase
    therapy methionine synthase: pernicious anemia, caused by Vitamin B12 deficiency, is caused by a lack of cofactor for the methionine synthase enzyme Recent...
    26 KB (2,919 words) - 01:51, 24 December 2024
  • enzymology, a nicotianamine synthase (EC 2.5.1.43) is an enzyme that catalyzes the chemical reaction 3 S-adenosyl-L-methionine ⇌ {\displaystyle \rightleftharpoons...
    1 KB (130 words) - 18:37, 23 January 2024
  • Thumbnail for Megaloblastic anemia
    Phenytoin Nitrous Oxide Erythroleukemia Inborn genetic mutations of the Methionine synthase gene Di Guglielmo's syndrome Congenital dyserythropoietic anemia...
    13 KB (1,250 words) - 09:07, 6 November 2024
  • Idaho, US Mill test report (metals industry) Methionine synthase, responsible for the regeneration of methionine from homocysteine MTR (software), or My traceroute...
    2 KB (256 words) - 05:55, 29 September 2024
  • Adenosyl-chloride synthase (EC 2.5.1.94, chlorinase, 5'-chloro-5'-deoxyadenosine synthase) is an enzyme with systematic name S-adenosyl-L-methionine:chloride adenosyltransferase...
    1 KB (110 words) - 12:59, 26 August 2023
  • 7-methylxanthine + S-adenosyl-L-methionine ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + H+ + theobromine Caffeine synthase is expressed in the...
    4 KB (370 words) - 13:24, 26 August 2023
  • Thumbnail for 1-Aminocyclopropane-1-carboxylate synthase
    acid synthase, aminocyclopropanecarboxylate synthase, ACC synthase, and S-adenosyl-L-methionine methylthioadenosine-lyase. This enzyme participates...
    21 KB (2,514 words) - 10:32, 18 November 2024
  • Thumbnail for Vitamin B12-binding domain
    containing the cobalamin-binding domain include: Animal and prokaryotic methionine synthase (EC 2.1.1.13), which catalyse the transfer of a methyl group from...
    7 KB (770 words) - 17:55, 11 March 2024