molecular biology, palmitoylation is the covalent attachment of fatty acids, such as palmitic acid, to cysteine (S-palmitoylation) and less frequently...

postsynaptic membrane. Thus, palmitoylation can play a role in the regulation of neurotransmitter release. Palmitoylation mediates the affinity of a protein...

are instead attached to the membrane via lipid modifications such as palmitoylation. Tail-anchored proteins can be inserted into the plasma membrane, endoplasmic...

Ras is attached to the cell membrane owing to its prenylation and palmitoylation (HRAS and NRAS) or the combination of prenylation and a polybasic sequence...

by the addition of a palmitoyl group in a process known as palmitoylation. Palmitoylation is important for localisation of many membrane proteins. Palmitic...

compartmentalization within the cell and within cell membranes. For lipid rafts, palmitoylation regulates raft affinity for the majority of integral raft proteins....

1016/j.cbpa.2007.05.002. PMID 17500024. Smotrys JE, Linder ME (2004). "Palmitoylation of intracellular signaling proteins: regulation and function". Annual...

structural theme among GPCRs is palmitoylation of one or more sites of the C-terminal tail or the intracellular loops. Palmitoylation is the covalent modification...

sequestered into cholesterol-dependent lipid domains (green lipids) by palmitoylation. PLD also binds PIP2(red hexagon) domains (grey shading) located in...

modifications such as phosphorylation, hydroxylation, sulfonation, palmitoylation, glycosylation, and disulfide formation. In general, peptides are linear...

most abundant palmitoylated proteins in brain (Neuron, 1998), and that palmitoylation localizes PSD-95 to synaptic sites (Neuron, 1999). They found that synaptic...

addition of fatty acids to particular amino acids (e.g. myristoylation, palmitoylation or palmitoleoylation). Different types of fatty acids engage in global...

human gene. The HHAT gene encodes an enzyme that catalyzes N-terminal palmitoylation of sonic hedgehog. Mutations in HHAT produce a phenotype that is similar...

(a type of acylation), attachment of myristate, a C14 saturated acid palmitoylation (a type of acylation), attachment of palmitate, a C16 saturated acid...

investigated. Some members of the family such as ZDHHC3 and ZDHHC7 enhance palmitoylation of proteins such as PSD-95, SNAP-25, GAP43, Gαs. Others such as ZDHHC9...

through a cysteine amino acid. A prominent type of protein S-acylation is palmitoylation, which promotes lipid membrane association of the protein, for instance...

started for children with progeria. In signal transduction via G protein, palmitoylation of the α subunit, prenylation of the γ subunit, and myristoylation is...

Flavin linkage Topaquinone (TPQ) formation Detyrosination Cysteine Palmitoylation Prenylation Aspartate Succinimide formation ADP-ribosylation Glutamate...

by palmitoylation. Palmitoylation is known to contribute to membrane association because it contributes to enhanced hydrophobicity. Palmitoylation is...

fatty acid acyl chains on the cytoplasmic side of the cell membrane via palmitoylation, myristoylation, or prenylation. On the exoplasmic face of the cell...

conserved throughout the tetraspanin family. Also containing distinct palmitoylation sites that allows CD9 to interact with lipids and other proteins. Tetraspanin...

adds a negative charge to a previously neutral site. prenylation and palmitoylation − C ( = O ) − ( C H 2 ) 14 − C H 3 {\displaystyle \mathrm...

dissociation of myristoylated proteins from membranes. Myristoylation and palmitoylation are commonly coupled modifications. Myristoylation alone can promote...

beta2-adrenergic receptor, and PSD-95. https://swisspalm.org/enzymes The protein palmitoylation is a reversible process. The addition of palmitoyl group increase the...

single name. For example, mGFP often refers to a GFP with an N-terminal palmitoylation that causes the GFP to bind to cell membranes. However, the same term...

capabilities, including phosphorylation, glycosylation, myristoylation and palmitoylation. Similar to mammalian cells, proteins expressed are mostly soluble,...

Lingwood, D; Grzybek, M; Coskun, U; Simons, K (21 December 2010). "Palmitoylation regulates raft affinity for the majority of integral raft proteins"...

M, Yamamoto H, Izumi S, Kikuchi A (March 2007). "Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling". The Biochemical...

"Human serotonin1B receptor expression in Sf9 cells: phosphorylation, palmitoylation, and adenylyl cyclase inhibition". Biochemistry. 32 (43): 11727–33....

preventing the virus from entering the host cell. It does this by S-palmitoylation, a process where fatty acids are added to an amino acid named cysteine...